Safety of sodium fluorescein for in vivo study of skin

Skin Research and Technology

Volumn 12, Issue 3, 2006, Pages 155-161

  O'goshi, Ken Ichiro ^a,b   Serup, Jørgen ^a  

^a BISPEBJERG HOSPITAL   (Denmark)

^b NONE   (Denmark)

Author keywords

Confocal scanning laser microscopy; Fluorescence; In vivo skin; Intradermal use; Safety; Sodium fluorescein; Toxicity

Indexed keywords

CONFOCAL SCANNING LASER MICROSCOPY; IN VIVO SKIN; INTRADERMAL USE; SODIUM FLUORESCEIN;

ANGIOGRAPHY; LASER APPLICATIONS; MICROSCOPIC EXAMINATION; NONINVASIVE MEDICAL PROCEDURES; SAFETY FACTOR; TOXICITY;

SKIN;

FLUORESCEIN ISOTHIOCYANATE; FLUORESCEIN SODIUM; ISOSULFAN BLUE; TECHNETIUM SULFUR COLLOID TC 99M;

ABDOMINAL DISCOMFORT; ACUTE HEART INFARCTION; AIRWAY OBSTRUCTION; ANAPHYLAXIS; BOLUS INJECTION; BRADYCARDIA; CLONUS; CONFUSION; CRANIAL NEUROPATHY; DIAGNOSTIC VALUE; DIAPHORESIS; DISORIENTATION; DIZZINESS; DOSE RESPONSE; DROWSINESS; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG ERUPTION; DRUG EXCRETION; DRUG FATALITY; DRUG FEVER; DRUG HYPERSENSITIVITY; DRUG METABOLISM; DRUG SAFETY; DRUG STRUCTURE; DYSPNEA; EPILEPTIC STATE; FACE EDEMA; FLUORESCENCE ANGIOGRAPHY; FLUSHING; GRAND MAL SEIZURE; HEART ARREST; HEART ATRIUM FIBRILLATION; HEART DISEASE; HOARSENESS; HUMAN; HYPESTHESIA; HYPOTENSION; IN VIVO STUDY; INCONTINENCE; INJECTION SITE ERYTHEMA; INJECTION SITE PAIN; INJECTION SITE PRURITUS; LARYNX EDEMA; LUNG EDEMA; MENINGITIS; MUSCLE WEAKNESS; NAUSEA AND VOMITING; NERVE PARALYSIS; NEUROTOXICITY; NONHUMAN; OPISTHOTONUS; PARESTHESIA; PHOTOSENSITIVITY; PHOTOTOXICITY; RESPIRATORY ARREST; RESPIRATORY DISTRESS; RESPIRATORY TRACT DISEASE; RETROSTERNAL PAIN; REVIEW; SHOCK; SIDE EFFECT; SKIN BLOOD FLOW; SNEEZING; SWEATING; SYNCOPE; SYSTEMATIC REVIEW; SYSTEMIC DISEASE; TACHYCARDIA; TACHYPNEA; THORAX PAIN; THROMBOPHLEBITIS; TONIC CLONIC SEIZURE; URTICARIA; VEIN INSUFFICIENCY;

ADMINISTRATION, ORAL; FLUORESCEIN; HUMANS; INJECTIONS, INTRAVENOUS; INJECTIONS, SPINAL; SAFETY; SKIN;

EID: 33745592810     PISSN: 0909752X     EISSN: 16000846     Source Type: Journal    
DOI: 10.1111/j.0909-752X.2006.00147.x     Document Type: Review

References (46)

1. Veiro JA, Cummins PG. Imaging of skin epidermis from various origins using confocal laser scanning microscopy. Dermatoloy 1994; 189: 16-22.
2. Klose AD, Gericke KR. Fluorescein as a circulation determinant. Ann Pharmacolotherap 1994; 28: 891-893.
3. Lange K, Boyd LJ. The use of fluorescein to determinate the adequacy of the circuration. Med Clin North Am 1942; 26: 943-952.
4. Bollinger A, Frey J, Jäger K, Furrer J, Segalis J, Siegenthaler W. Patterns of diffusion through skin capillaries in patients with long-term diabetes. N Engl J Med 1982; 7: 1305-10.
5. Perbeck L, Sevastik B, Sonnenfield T. The transcapillary exchange of sodium fluorescein in ischemic limbs measured by fluorescein flowmetry. Clin Physiol 1987; 7: 9-103.
6. Jager J, Oomen PHN, Sluiter WJ, Reitsma WD, Smit AJ. Improved reproducibility of the 'large window' method of assessing transcapillary and interstitial fluorescein diffusion in the skin in healthy subjects and in subjects with insulin-de-pendent diabetes mellitus. Int J Micocirc Clin Exp 1997; 17: 150-158.
7. Lund F, Gottlieb I, Inacio J. Evaluation of microvascular permeability by dermatofluoroscopy (DFG) from a finger in a diabetics and non-diabetics: With a preliminary study on the effect of hydroxyethyl-rutosides (HR). Phlebology 1990; 5 (Suppl 1): 33-40.
8. Lange K, Krewer SE. The dermatofluorometer. J Lab Clin Med 1943; 28: 1746-1750.
9. Silverman DG, LaRossa DD, Barlow CH, Bering TG, Popky LM, Smith TC. Quantification of tissue fluorescein delivery of predication of flap viability with the fiberoptic dermofluorometer. Plast Reconstr Surg 1980; 66: 545-553.
10. Lipson BK, Yannuzzi LA. Complications of intravenous fluorescein injections. Int Ophthalmol Clin 1989; 29: 200-500.
11. Mullins JM. Overview of fluorophores. Methods Mol Biol 1994; 34: 107-116.
12. Dollery C. Therapeutic drugs. Fluorescein, Vol. 1, 2nd edn, Edinburgh: Churchill Livingstone, 1999: 99-101.
13. Dearman RJ, Cumberbatch M, Hilton J. Influence of dibuthyl phthalate on dermal sensitization to fluorescein isothiocyanate. Fundam Appl Toxicol 1996; 33: 24-30.
14. Kersey TW, Van Eyk J, Lannin DR et al. Comparison of intradermal and subcutaneous injections in lymphatic mapping. J Surgical Res 2001; 96: 255-259.
15. Hara T, Inami M, Kara T. Efficacy and safety of fluorescein angiography with orally administered sodium fluorescein. Am J Ophthalmol 1998; 126: 560-564.
16. Watson AP, Rosen ES. Oral fluorescein angiography: Reassessment of its relative safety and evaluation of optimum conditions with use of capsules. Br J Ophthalmol 1990; 47: 458-461.
17. Kinsella FP, Mooney DJ. Anaphylaxis following oral fluorescein angiography. Am J Ophthalmol 1988; 106: 745-756.
18. Gomez-Ulla F, Gutierrez C, Seoane I. Severe anaphylactic reaction to orally administered fluorescein. Am J Ophthalmol 1991; 112: 94.
19. James E. F. R. Martindale the extra pharmacopoeia. Fluorescein, 31st edn, London: Pharmaceutical Press, 1996: 1102-1103.
20. LaPiana FG, Penner R. Anaphylactoid reaction to intravenously administered fluorescein. Arch Ophthalmol 1698; 79: 161-162.
21. Deglin SM, Deglin EA, Chung EK. Acute myocardial infarction following fluorescein angiography. Heart Lung 1977; 6: 505-509.
22. Cunningham EE, Balu V. Cardiac arrest following fluorescein angiography. JAMA 1979; 242: 2431.
23. Heffner JE. Reactions to fluorescein. JAMA 1980; 243: 2029-2030.
24. Kearns GL, Williams BJ, Timmons OD. Fluorescein phototoxicity in a premature infant. J Pediatr 1985; 107: 796-798.
25. Kelly SP, MacDermott NJ, Saunders DC et al. Convulsion following intravenous fluorescein angiography. Br J Ophthalmol 1989; 73: 655-656.
26. Ascaso FJ, Tiestos MT, Navales J et al. Fatal acute myocardial infarction after intravenous fluorescein angiography. Retina 1993; 13: 238-239.
27. Lentner A, Bonier U. Photosensitivity reaction to intravenously administered fluorescein. Photodermatol Photoimmunol Photomed 1995; 11: 178-179.
28. Kirson LE, Wilson ME. Atrial fibrillation associated with intravenous fluorescein. Anesth Analg 1987; 66: 283-286.
29. Gombos GM, Lieberman RM. Seizures associated with fluorescein angiography. Ann Ophthalmol 1989; 21: 89-90.
30. Stein MR, Parker CW. Reactions following intravenous fluorescein. Am J Ophthalmol 1971; 72: 861-868.
31. Bloome MA. Fluorescein angiography risks. Vision Res 1980; 20: 1083-1097.
32. Pacurariu RI. Low incidence of side effects following intravenous fluorescein angiography. Ann Ophthalmol 1982; 14: 32-36.
33. Marcus DF, Bovino JA, Williams D. Adverse reactions during intravenous fluorescein angiography. Arch Ophthalmol 1984; 102: 825.
34. Yannuzzi LA, Rohrer KT, Tindel LJ et al. Fluorescein angiography complication survey. Ophthalmology 1986; 93: 611-617.
35. Karhunen U, Raitta C, Kala R. Adverse reactions to fluorescein angiography. Acta Ophthalmol 1986; 64: 282-286.
36. Mahaley MS, Odom GL. Case reports and technical notes: Complications following intrathecal injection of fluorescein. J Neurosurg 1966; 25: 298-299.
37. Wallace JD, Weintraub MI, Mattson RH et al. Status epilepticus as a complication of intrathecal fluorescein. J Neurosurg 1972; 36: 659-670.
38. Moseley JI, Carton CA, Stern WE. Spectrum of complications in the use of intrathecal fluorescein. J Neurosurg 1978; 48: 765-767.
39. Coeytaux A, Reverdin A, Jallon P et al. Non convulsive status epilepticus following intrathecal fluorescein injection. Acta Neurol Scand 1999; 100: 278-280.
40. Scavone J, Fraser D. Intrathecal sodium fluorescein. Drug Intell Clin Pharm 1983; 17: 186-187.
41. Scraff CE. A strategy to enable the in vivo examination of human skin using confocal microscopy. Department of Medicine (Dermatology), St Vincent Hospital, Melbourne. School of Medicine, Faculty of Medicine, Dentistry and Health Sciences. The University of Melbourne, January 2001.
42. Bollinger A, Jäger K, Sgier F et al. Fluorescence microlymphography. Circulation 1981; 64: 1195-1200.
43. Bollinger A, Pfister G, Hoffmann U et al. Fluorescence microlymphography in chronic venous incompetence. Int Angiol 1989; 8: 23-26.
44. Stanton AWB, Kadoo P, Mortimer PS et al. Quntification of the initial lymphatic network in normal human forearm skin using fluorescence microlymphography and stereological methods. Microvascular Res 1997; 54: 156-163.
45. Mellor RH, Stanton AWB, Azarbod P et al. Enhanced cutaneous lymphatic network in the forearms of women with postmastectomy oedema. J Vascular Res 2000; 37: 501-512.
46. Leu AJ, Husmann MJW, Held T et al. Measurement of the lymphatic clearance of the human skin using a fluorescent tracer. J Vascular Res 2001; 38: 423-431.