Parametric study to optimize the processing parameters and the physical properties of porous PLGA 85/15 scaffold

Annual Technical Conference - ANTEC, Conference Proceedings

Volumn 3, Issue , 2006, Pages 1371-1375

  Perron, J K ^a   Naguib, H E ^b   Daka, J ^c   Chawla, A ^c  

^a UNIVERSITY OF OTTAWA   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c HEALTH CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FOAMS; LEACHING; OPTIMIZATION; POLYMERS; POROSITY; SATURATION (MATERIALS COMPOSITION); SODIUM CHLORIDE;

GAS SATURATION; PORE DENSITY; POROUS SCAFFOLDS; SALT LEACHING;

SCAFFOLDS;

EID: 33745586314     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (21)

1. Sheridan M.H., Shea L.D., Peters M.C., Mooney D.J., Bioabsorbable polymer scaffolds for tissue engineering capable of sustained growth factor delivery, Journal of Controlled Release, 64, 91-102 (2000)
2. Yang S., Leong K.P., Du S., Chua C.K., The design of scaffolds for use in tissue enginerring. Part I. Traditional factors, Tissue Engineering, 7, 679-689 (2001)
3. Lanza R.P., Langer R., Chick W.L., Principles of Tissue Engineering, First edition. Landes Bioscience, Texas, (1997)
4. Cooper M.L., Hansbrough J.F., Spielvogel R.L., et al., In vivo optimization of a living dermal substitute employing cultured human fibroblasts on a biodegradable polyglycolic acid or polyglactin mesh, Biomaterials, 12, 243-248 (1991)
5. Cima L.G., Vacanti J.P.,Vacanti C., et al., Tissue engineering by cell transplantation using degradable polymer substrates, Journal of Biomechanical Engineering, 113, 143-151 (1991)
6. Evan G.R.D., Brandt K., Widmer S., et al., In vivo evaluation of poly (L-lactic acid) porous conduits for peripheral nerve regeneration, Biomaterials, 20, 1109-1115 (1999)
7. Neuenschwander S., Hoerstrup S.P., Heart valve tissue engineering, Transplant Immunology, 12, 359-365 (2004)
8. Nikolovski J., Mooney D.J., Smooth muscle cell adhesion to tissue engineering scaffold, Biomaterials, 21, 2025-2032 (2000)
9. Kim B.S., Mooney D.J., Engineering smooth muscle tissue with a predefined structure, Journal of Biomedical Materials Research, 41, 322-332 (1998)
10. Putnam A.J., Mooney D.J., Tissue engineering using synthetic extracellular matrices, Nature Medecine, 2, 824-826 (1996)
11. Langer R., Tissue Engineering: Status and Challenges, The Journal of Regenerative Medicine, 1, 5-6 (2000)
12. Langer R.S., Vacanti J.P., Tissue engineering: The challenges ahead, Scientific American Inc., 86-89 (1999)
13. Mikos A.G., Temenoff J.S., Formation of highly porous biodegradable scaffolds for tissue engineering, Electronic Journal of Biotechnology, 3, 114-119 (2000)
14. Harris L.D., Kim B.S., Mooney D.J., Open pore biodegradable matrices formed with gas foaming, Journal of Biomedical Materials Research, 42, 396-402 (1998)
15. Chen G., Ushida T., Tateishi T., Development of biodegradable porous scaffolds for tissue engineering, Materials Science and Engineering, 17, 63-69 (2001)
16. Guan L., Davies I.E., Preparation and characterization of a highly macroporous biodegradable composite tissue engineering scaffold, Journal of Biomedical Materials Research Part A, 71A, 480-487 (2004)
17. 2 as solvent: Structural characterization, Journal of Biomedical Materials Research, 62, 89-98 (2002)
18. Mooney D.J., Baldwin D.F., Suh N.P., Vacanti J.P., Langer R., Novel approach to fabricate porous sponges of poly (D,L-lactic-co-glycolic acid) without the use of organic solvents, Biomaterials, 17, 1417-1422 (1996)
19. Singh L., Kumar V., Ratner B.D., Generation of porous microcellular 85/15 poly (DL-lactide-co-glycolide) foams for biomedical applications, Biomaterials, 25, 2611-2617 (2004)
20. Baldwin D.F., Park C.B., Suh N.P., A microcellular Processing Study of Poly(Ethylene Terephthalate) in the amorphous and semicrystalline States. Part I: Microcell Nucleation, Polymer Engineering and Science, 36, 1437-1445 (1996)
21. Baldwin D.F., Park C.B., Suh N.P., A microcellular Processing Study of Poly(Ethylene Terephthalate) in the amorphous and semicrystalline States. Part II: Cell Growth and Process Design, Polymer Engineering and Science, 36, 1446-1453 (1996)