Proliferative activity detected by Ki67 correlates with poor outcome in Merkel cell carcinoma [8]

Histopathology

Volumn 49, Issue 5, 2006, Pages 551-553

  Koljonen, V ^a   Tukiainen, E ^a   Haglund, C ^a   Bohling T ^b  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

KI 67 ANTIGEN;

CANCER RECURRENCE; CANCER SURVIVAL; CELL ACTIVITY; CELL PROLIFERATION; CORRELATION ANALYSIS; DISEASE COURSE; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; LETTER; LYMPH NODE METASTASIS; MERKEL CELL TUMOR; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION;

CARCINOMA, MERKEL CELL; CELL PROLIFERATION; DISEASE PROGRESSION; HUMANS; KI-67 ANTIGEN; NEOPLASM METASTASIS; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; SKIN NEOPLASMS;

EID: 33745567489     PISSN: 03090167     EISSN: 13652559     Source Type: Journal    
DOI: 10.1111/j.1365-2559.2006.02511.x     Document Type: Letter

References (8)

1. Brissett AE, Olsen KD, Kasperbauer JL et al. Merkel cell carcinoma of the head and neck: a retrospective case series. Head Neck 2002; 24; 982-988.
2. Moll I, Zieger W, Schmelz M. Proliferative Merkel cells were not detected in human skin. Arch. Dermatol. Res. 1996; 288; 184-187.
3. Llombart B, Monteagudo C, Lopez-Guerrero JA et al. Clinicopathological and immunohistochemical analysis of 20 cases of Merkel cell carcinoma in search of prognostic markers. Histopathology 2005; 46; 622-634.
4. Fernandez-Figueras MT, Puig L, Musulen E et al. Prognostic significance of p27Kip1, 45Skp2 and Ki67 expression profiles in Merkel cell carcinoma, extracutaneous small cell carcinoma, and cutaneous squamous cell carcinoma. Histopathology 2005; 46; 614-621.
5. Parrado C, Bjornhagen V, Eusebi V et al. Prognosticating tools in primary neuroendocrine (Merkel-cell) carcinomas of the skin: histopathological subdivision, DNA cytometry, cell proliferation analyses (Ki-67-immunoreactivity) and NCAM immunohistochemistry. A clinicopathological study in 25 patients. Pathol. Res. Pract. 1998; 194; 11-23.
6. Erickson LA, Papotti M, Volante M, Jin L, Lewis JE, Lloyd RV. Merkel cell carcinomas: expression of S-phase kinase-associated protein 2 (Skp2), p27, and proliferation markers. Endocr. Pathol. 2003; 14; 221-229.
7. Carson HJ, Reddy V, Taxy JB. Proliferation markers and prognosis in Merkel cell carcinoma. J. Cutan. Pathol. 1998; 25; 16-19.
8. Fernandez-Figueras MT, Puig L, Musulen E et al. Prognostic significance of p27, p45 and Ki67 expression profiles in Merkel cell carcinoma, extracutaneous small cell carcinoma, and cutaneous squamous cell carcinoma. Histopathology 2005; 46; 614-621.