Bioresorbable poly(ester-ether urethane)s from L-lysine diisocyanate and triblock copolymers with different hydrophilic character

Journal of Biomedical Materials Research - Part A

Volumn 76, Issue 4, 2006, Pages 729-736

  Abraham, Gustavo A ^a   Marcos Fernández, Angel ^b   San Román, Julio ^b  

^a Instituto de Investigaciones en Ciencia y Tecnologia de Materiales   (Argentina)

^b INSTITUTO DE CIENCIA Y TECNOLOGÍA DE POLÍMEROS   (Spain)

Author keywords

Bioresorbable polyurethanes; Lysine diisocyanate; Poly( caprolactone); Poly(ethylene oxide); Triblock copolymers

Indexed keywords

BIORESORBABLE POLYURETHANES; LYSINE DIISOCYANATE;

BLOCK COPOLYMERS; CATALYSTS; HYDROPHILICITY; POLYCAPROLACTONE; SIZE EXCLUSION CHROMATOGRAPHY; SYNTHESIS (CHEMICAL); X RAY DIFFRACTION ANALYSIS;

POLYURETHANES;

COPOLYMER; ESTRADIOL DERIVATIVE; LYSINE DERIVATIVE; LYSINE DIISOCYANATE; MACROGOL; POLY(ESTER ETHER URETHANE); POLYCAPROLACTONE; POLYMER; POLYURETHAN; UNCLASSIFIED DRUG; BIOMATERIAL; DRUG DERIVATIVE; ISOCYANIC ACID DERIVATIVE; LYSINE;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; GEL PERMEATION CHROMATOGRAPHY; HYDROLYSIS; HYDROPHILICITY; MOLECULAR WEIGHT; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; WATER TRANSPORT; X RAY DIFFRACTION; CHEMISTRY; MATERIALS TESTING;

BIOCOMPATIBLE MATERIALS; HYDROLYSIS; ISOCYANATES; LYSINE; MATERIALS TESTING; POLYMERS; POLYURETHANES; X-RAY DIFFRACTION;

EID: 33745538760     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.30540     Document Type: Article

References (20)

1. Lelah DL, Cooper SL. Polyurethanes in medicine. Boca Raton, FL: CRC Press; 1986.
2. Liu Q, Runt J, Felder G, Rosenberg G, Snyder AJ, Weiss WJ, Lewis J, Werley T. In vivo and in vitro stability of modified poly(urethane urea) blood sacs. J Biomater Appl 2000;14:349-366.
3. Santerre JP, Labow RS. The effect of hard segment size on the hydrolytic stability of polyether-urea-urethanes when exposed to cholesterol esterase. J Biomed Mater Res 1997;36:223-232.
4. Saad B, Hirt TD, Welti M, Uhlschmid GK, Neuenschwander P, Suter UW. Development of degradable polyesterurethanes for medical applications: in vitro and in vivo evaluations. J Biomed Mater Res 1997;36:65-74.
5. McGill DB, Motto JD. An industrial outbreak of toxic hepatitis due to methylene-dianiline. New Engl J Med 1974;291:278-282.
6. Bruin P, Veenstra GJ, Nijenhuis AJ, Pennings AJ. Design and synthesis of biodegradable poly(ester-urthane) elastomer networks composed of non-toxic building blocks. Makromol Chem Rapid Commun 1988;9:589-594.
7. Hettrich W, Becker R. New isocyanates from amino acids. Polymer 1997;38:2437-2445.
8. Skarja GA, Woodhouse KA. Synthesis and characterization of degradable polyurethanes elastomers containing an amino acid-based chain extender. J Biomater Sci Polym Ed 1998;9:271-295.
9. Bruin P, Smedinga J, Pennings AJ, Jonkman MF. Biodegradable lysine diisocyanate-based poly(glycolide-co-ε-caprolactone)-urethane network in artificial skin. Biomaterials 1990;11:291.
10. Perrin DE, English JP. Polycaprolactone. In: Domb AJ, Kost J, Wiseman DM, editors. Handbook of biodegradable polymers. Singapur: Harwood Academic Publishers; 1977. Chapter 3.
11. Merrill EW, Salzman EW. Polyethylene oxide as a biomaterial. ASAIO J 1983;6:60-64.
12. Silver JH, Myers CW, Lim F, Cooper SL. Effect of polyol molecular weight on the physical properties and haemocompatibility of polyurethanes containing polyethylene oxide macroglycols. Biomaterials 1994;15:695-704.
13. Cerrai P, Guerra GD, Lelli L, Tricoli M, Scarbati del Guerra R, Cascone MG, Giusti P. Poly(ester-ether-ester) block copolymers as biomaterials. J Mater Sci Mater Med 1994;5:33-39.
14. Li S-M, Garreau H, Vert M, Petrova T, Manolova N, Rashkov I. Hydrolylic degradation of poly(oxyethylene)-poly-(ε-capro-lactone) multiblock copolymers. J Appl Polym Sci 1998;68:989.
15. Cerrai P, Guerra GD, Tricoli M, Krajewski A, Guicciardi S, Ravaglioli A, Maltinti S, Masetti G. New composites of hydroxyapatite and bioresorbable macromolecular material. J Mater Sci Mater Med 1999;10:283-289.
16. Petrova T, Manolova N, Rashkov I, Li S, Vert M. Synthesis and characterization of poly(oxyethylene)-poly(caprolactone) multiblock copolymers. Polym Int 1998;45:419-426.
17. Cohn D, Stern T, Gonzalez MF, Epstein J. Biodegradable poly(ethylene oxide)/poly(ε-caprolactone) multiblock copolymers. J Biomed Mater Res 2002;59:273-281.
18. Marcos-Fernández A, Abraham GA, Simões de Sousa A, San Román J. Amino-acid based non-toxic biodegradable poly(urethane-urea)s. Proceeding of the World Polymer Congress MACRO2004. 40th International Symposium on Macromolecules, 4-9 July 2004, Paris, France.
19. Marcos-Fernández A, Abraham GA, Valentín JL, San Román J. Síntesis y caracterización de poliuretanos biodegradables con ajuste de la hidrofilicidad/hidrofobicidad. IX Simposio Latino-americano de Polímeros, SLAP 2004, 11-16 July 2004, Valencia, Spain.
20. Pasch H, Rode K. Use of matrix-assisted laser desorption/ionization mass spectrometry for molar mass-sensitive detection in liquid chromatography of polymers. J Chromatogr 1995;A699:21.