Studies on Phage Displayed Mimotopes of a Protective Monoclonal Antibody (SSj14) Against Schistosoma japonicum

Chinese Journal of Biotechnology

Volumn 22, Issue 1, 2006, Pages 119-124

  WANG, Xin Zhi ^a,b   FU, Zhi Qiang ^a   HUANG, Shao Peng ^a   ZHU, Guo Qiang ^b   CAI, You Min ^a   LIN, Jiao Jiao ^a  

^a AGRO ENVIRONMENTAL PROTECTION INSTITUTE   (China)

^b YANGZHOU UNIVERSITY   (China)

Author keywords

IL 12; McAb SSj14; mimicking epitope; phage display; Schistosoma japonicum

Indexed keywords

EPITOPE; HELMINTH ANTIBODY; INTERLEUKIN 12; MONOCLONAL ANTIBODY; PARASITE ANTIGEN; PEPTIDE LIBRARY;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BLOOD; IMMUNOLOGY; MALE; MOLECULAR MIMICRY; MOUSE; SCHISTOSOMA JAPONICUM; SCHISTOSOMIASIS JAPONICA; VACCINATION;

ANIMALS; ANTIBODIES, HELMINTH; ANTIBODIES, MONOCLONAL; ANTIGENS, HELMINTH; EPITOPES; INTERLEUKIN-12; MALE; MICE; MICE, INBRED BALB C; MOLECULAR MIMICRY; PEPTIDE LIBRARY; SCHISTOSOMA JAPONICUM; SCHISTOSOMIASIS JAPONICA; VACCINATION;

SCHISTOSOMA JAPONICUM;

EID: 33745528600     PISSN: 18722075     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1872-2075(06)60009-5     Document Type: Article

References (14)

1. Pan H., Huang D., and Wang K. Approach to sur- veillance and consolidation during past 15 years after elimination of schistosomiasis in Shanghai. Acta Tropica 82 2 (2002) 301-303
2. Ye P., Tian E., Lin J., et al. Preliminary studies on the synergestic effect of monoclonal antibody and drugs in killing adult worms of Schistosoma japonicum. Chin J Schisto Control 6 6 (1994) 327-330
3. Smith G., and Scott J. Libraries of peptides and proteins displays on filamentous phage. Methods Enzymol 217 (1993) 228-257
4. Shu X., Yi X., Zeng X., et al. Immuno- screening of phage random peptide library with sera from patients with Schistosomasis japonica. Cell Mol Immunol 16 2 (2000) 109-112
5. Scott J., and Smith G. Searching for peptide ligands with an epitope library. Science 249 (1990) 386-390
6. Kotz J., Bond C., and Cochran A. Phage-display as a tool for quantifying protein stability determinants. Eur J Biochem 271 9 (2004) 1609-1614
7. Wang L., and Yu M. Epitope identification and discovery using phage display libraries: applications in vaccine development and diagnostics. Curr Drug Targets 5 1 (2004) 1-15
8. Naz R. Human synthetic peptide vaccine for contraception targeting sperm. Arch Androl 50 2 (2004) 113-119
9. Yuan S., Yi X., Zeng X., et al. Protective immunity against Schistosoma japonicum induced by epitopes mimicking cercariae antigens of Schistosoma japonicum. China Tropical Medicine 2 3 (2002) 291-294
10. Burritt J., Bond C., Doss K., et al. Filamentous phage display of oligopeptide libraries. Anal Biochem 238 1 (1996) 1-13
11. Barlow D., Edwards M., et al. Continuous and discontinuous protein antigenic determinants. Nature 322 (1986) 747-748
12. Hoffmann K., Caspar P., Cheever A., et al. IFN-gamma, IL-12, and TNF-alpha are required to maintain reduced liver pathology in mice vaccinated with Schistosoma mansoni eggs and IL-12. J Immunol 161 8 (1998) 4201-4210
13. Anderson S., et al. In the absence of IL-12, the induction of Th1-mediated protective immunity by the attenuated schistosome vaccine is impired, revealing an alternative pathway with Th2-type characteristics. Eur J Immunol 28 (1998) 2827-2838
14. Wynn T., et al. IL-12 enhances vaccines vaccine-induced immunity to schistosoma mansoni in mice and decreases T helper 2 cytokine expression, IgE production and tissue eosinophilia. J Immunol 154 (1995) 4701-4709