Transdermal nicotine patch enhances type I collagen synthesis in abstinent smokers

Wound Repair and Regeneration

Volumn 14, Issue 3, 2006, Pages 247-251

  Sørensen, Lars T ^a,c   Jorgensen, Lars N ^a   Zillmer, Rikke ^a   Vange, Jakob ^b   Hemmingsen, Ulla ^a   Gottrup, Finn ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b COLOPLAST Research ^*  (Denmark)

^c BISPEBJERG HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; HYDROXYLYSINE; HYDROXYPROLINE; NICOTINE PATCH; PLACEBO; POLITEF; PROCOLLAGEN; PROLINE;

ABSTINENCE; ADULT; ARTICLE; CIGARETTE SMOKING; CLINICAL TRIAL; COLLAGEN SYNTHESIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEVICE REMOVAL; DOUBLE BLIND PROCEDURE; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GRANULATION TISSUE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IMPLANT; MAJOR CLINICAL STUDY; MALE; NICOTINE REPLACEMENT THERAPY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SMOKING CESSATION; WITHDRAWAL SYNDROME;

ADMINISTRATION, CUTANEOUS; ADULT; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLLAGEN TYPE I; DOUBLE-BLIND METHOD; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; HYDROXYPROLINE; MALE; NICOTINE; PROLINE; SMOKING; SMOKING CESSATION; WOUND HEALING;

EID: 33745523819     PISSN: 10671927     EISSN: 1524475X     Source Type: Journal    
DOI: 10.1111/j.1743-6109.2006.00118.x     Document Type: Article

References (29)

1. Sorensen LT, Hemmingsen U, Kallehave F, Wille-Jorgensen P, Kjaergaard J, Moller LN, Jorgensen T. Risk factors for tissue and wound complications in gastrointestinal surgery. Ann Surg 2005; 241: 654-8.
2. Sorensen LT, Karlsmark T, Gottrup F. Abstinence from smoking reduces incisional wound infection: a randomized controlled trial. Ann Surg 2003; 238: 1-5.
3. Kasperk R, Philipps B, Vahrmeyer M, Willis S, Schumpelick V. Risk factors for anastomosis dehiscence after very deep colorectal and coloanal anastomosis. Chirurg 2000; 71: 1365-9.
4. Fawcett A, Shembekar M, Church JS, Vashisht R, Springall RG, Nott DM. Smoking, hypertension, and colonic anastomotic healing; a combined clinical and histopathological study. Gut 1996; 38: 714-8.
5. Sorensen LT, Hemmingsen UB, Kirkeby LT, Kallehave F, Jorgensen LN. Smoking is a risk factor for incisional hernia. Arch Surg 2005; 140: 119-23.
6. Sorensen LT, Friis E, Jorgensen T, Vennits B, Andersen BR, Rasmussen GI, Kjaergaard J. Smoking is a risk factor for recurrence of groin hernia. World J Surg 2002; 26: 397-400.
7. Knuutinen A, Kokkonen N, Risteli J, Vahakangas K, Kallioinen M, Salo T, Jorsa T, Dikarinen A. Smoking affects collagen synthesis and extracellular matrix turnover in human skin. Br J Dermatol 2002; 146: 588-94.
8. Yin L, Morita A, Tsuji T. Alterations of extracellular matrix induced by tobacco smoke extract. Arch Dermatol Res 2000; 292: 188-94.
9. Jorgensen LN, Kallehave F, Christensen E, Siana JE, Gottrup F. Less collagen production in smokers. Surgery 1998; 123: 450-5.
10. Pihlajaniemi T, Myllyla R, Kivirikko KI. Prolyl 4-hydroxylase and its role in collagen synthesis. J Hepatol 1991; 13 (Suppl. 3): S2-7.
11. Wicke C, Halliday B, Scheuenstuhl H, Foree EF, Hunt TK. Examination of expanded polytetrafluoroethylene wound healing models. Wound Rep Reg 1995; 3: 284-91.
12. Jensen JA, Goodson WH, Williams H, Hunt TK. Cigarette smoking decreases tissue oxygen. Arch Surg 1991; 126: 1131-4.
13. Jorgensen LN, Kallehave F, Karlsmark T, Vejlsgaard GL, Gottrup F. Evaluation of the wound healing potential in human beings from the subcutaneous insertion of expanded polytetrafluoroethylene tubes. A methodological study. Wound Rep Reg 1994; 2: 20-30.
14. Kaplan LA. Classifications and description of proteins, lipids, and carbohydrates. In: Kaplan LA, Pesce AJ, editors. Clinical chemistry: theory, analysis, and correlation. St. Louis: C.V. Mosby, 1989: 751-65.
15. Orum O, Hansen M, Jensen CH, Sorensen HA, Jensen LB, Horslev-Petersen K, Teisner B. Procollagen type I N-terminal propeptide (PINP) as an indicator of type I collagen metabolism: ELISA development, reference interval, and hypovitaminosis D induced hyperparathyroidism. Bone 1996; 19: 157-63.
16. Perkins SL, Livesey JF, Escares EA, Belcher JM, Dudley DK. High-performance liquid-chromatographic method compared with a modified radioimmunoassay of cotinine in plasma. Clin Chem 1991; 37: 1989-93.
17. Sato S, Nishimura K, Koyama H, Tsukino M, Oga T, Hajiro T, Mishima M. Optimal cutoff level of breath carbon monoxide for assessing smoking status in patients with asthma and COPD. Chest 2003; 124: 1749-54.
18. Morecraft R, Blair WF, Brown TD, Gable RH. Acute effects of smoking on digital artery blood flow in humans. J Hand Surg 1994; 19: 1-7.
19. Astrup P, Kjeldsen K. Carbon monoxide, smoking, and atherosclerosis. Med Clin North Am 1974; 58: 323-50.
20. Benowitz NL. Clinical pharmacology of nicotine. Ann Rev Med 1986; 37: 21-32.
21. Astrup P, Hellung-Larsen P, Kjeldsen K, Mellemgaard K. The effect of tobacco smoking on the dissociation curve of oxyhemoglobin. Investigations in patients with occlusive arterial diseases and in normal subjects. Scand J Clin Lab Invest 1966; 18: 450-7.
22. Greif R, Akca O, Horn EP, Kurz A, Sessler DI. Supplemental perioperative oxygen to reduce the incidence of surgical-wound infection. Outcomes research group. N Engl J Med 2000; 342: 161-7.
23. Sorensen LT, Nielsen HB, Kharazmi A, Gottrup F. Effect of smoking and abstention on oxidative burst and reactivity of neutrophils and monocytes. Surgery 2004; 136: 1047-53.
24. Ambrose JA, Barua RS. The pathophysiology of cigarette smoking and cardiovascular disease: an update. J Am Coll Cardiol 2004; 43: 1731-7.
25. Lykkesfeldt J, Christen S, Wallock LM, Chang HH, Jacob RA, Ames BN. Ascorbate is depleted by smoking and repleted by moderate supplementation: a study in male smokers and nonsmokers with matched dietary antioxidant intakes. Am J Clin Nutr 2000; 71: 530-6.
26. Faruque MO, Khan MR, Rahman MM, Ahmed F. Relationship between smoking and antioxidant nutrient status. Br J Nutr 1995; 73: 625-32.
27. Lehninger AL. Vitamins and trace elements in the function of enzymes. Principles of biochemistry. New York: Worth Publishers Inc., 1982: 249-76.
28. Arredondo J, Hall LL, Ndoye A, Nguyen VT, Chernyavsky AI, Bercovich D, Orr-Urtreger A, Beavdet AL, Grando SA. Central role of fibroblast alpha3 nicotinic acetylcholine receptor in mediating cutaneous effects of nicotine. Lab Invest 2003; 83: 207-25.
29. Jacobi J, Jang JJ, Sundram U, Dayoub H, Fajardo LF, Cooke JP. Nicotine accelerates angiogenesis and wound healing in genetically diabetic mice. Am J Pathol 2002; 161: 97-104.