γ-Tocopherol attenuates MPTP-induced dopamine loss more efficiently than α-tocopherol in mouse brain

Neuroscience Letters

Volumn 403, Issue 1-2, 2006, Pages 136-140

  Itoh, Nanako ^a   Masuo, Yoshinori ^a   Yoshida, Yasukazu ^a   Cynshi, Osamu ^b   Jishage, Kou ichi ^b   Niki, Etsuo ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b CHUGAI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Tocopherol; Tocopherol; Dopamine; MPTP

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ALPHA TOCOPHEROL; DOPAMINE; GAMMA TOCOPHEROL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CONTROLLED STUDY; CORPUS STRIATUM; DIET SUPPLEMENTATION; DOPAMINE RELEASE; DOPAMINERGIC NERVE CELL; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; MOUSE; NERVE DEGENERATION; NEUROCHEMISTRY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ALPHA-TOCOPHEROL; ANIMALS; ANTIOXIDANTS; BRAIN; DOPAMINE; GAMMA-TOCOPHEROL; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; VITAMINS;

EID: 33745512853     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2006.04.028     Document Type: Article

References (30)

1. Fariss M.W., and Zhang J.G. Vitamin E therapy in Parkinson's disease. Toxicology 189 (2003) 129-146
2. Feng Z.H., Wang T.G., Li D.D., Fung P., Wilson B.C., Liu B., Ali S.F., Langenbach R., and Hong J.S. Cyclooxegenase-2-deficient mice are resistant to 1-methyl-4-phenyl 1,2,3,6-tetrahydropyridine-induced damage of dopaminergic neurons in the substantia nigra. Neurosci. Lett. 329 (2002) 354-358
3. Hald A., and Lotharius J. Oxidative stress and inflammation in Parkinson's disease: is there a causal link?. Exp. Neurol. 193 (2005) 279-290
4. Hensley E., Benaksas E.J., Bolli R., Comp P., Grammas P., Hamdheydari L., Mou S., Pye Q.N., Stoddard M.F., Wallis G., Williamson K.S., West M., Wechter W.J., and Floyd R.A. New perspectives on Vitamin E: γ-tocopherol and carboxyethylhydroxychroman metabolites in biology and medicine. Free Rad. Biol. Med. 36 (2004) 1-15
5. Hunot S., Vila M., Teismann P., Davis R.J., Hirsch E.C., Przedborski S., Rakic P., and Flavell R.A. JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 665-670
6. Jenner P. Oxidative stress in Parkinson's disease. Ann. Neurol. Suppl. 3 (2003) S26-S36
7. Jiang Q., and Ames B.N. γ-Tocopherol, but not α-tocopherol, decreases proinflammatory eicosanoids and inflammation damage in rats. FASEB J. 17 (2003) 816-822
8. Jiang Q., Elson-Schwab I., Courtemanche C., and Ames B.N. γ-Tocopherol and its major metabolite, in contrast to α-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cells. Proc. Natl. Acad. Sci. U.S.A. 97 (2000) 11494-11499
9. Jiang Q., Wong J., Fyrst H., Saba J.D., and Ames B.N. γ-Tocopherol or combinations of Vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 17825-17830
10. Jishage K., Arita M., Igarashi K., Iwata T., Watanabe M., Ogawa M., Ueda O., Kamada N., Inoue K., Arai H., and Suzuki H. α-Tocopherol transfer protein is important for the normal development of placental labyrinthine trophoblasts in mice. J. Biol. Chem. 276 (2001) 1669-1672
11. Li M.H., Jang J.H., and Surh Y.J. Nitric oxide induces apoptosis via AP-1-driven upregulation of COX-2 in rat pheochromocytoma cells. Free Rad. Biol. Med. 39 (2005) 890-899
12. Mandel S., Grunblatt E., Riederer P., Gerlach M., Levites Y., and Youdim M.B. Neuroptotective strategies in Parkinson's disease: an update on progress. CNS Drugs 17 (2003) 729-762
13. Martinovits G., Melamed E., Cohen O., Rosenthal J., and Uzzan A. Systemic administration of antioxidants does not protect mice against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP). Neurosci. Lett. 69 (1986) 192-197
14. Mihatsch W., Russ H., Gerlach M., Riederer P., and Przuntek H. Treatment with antioxidants does not prevent loss of dopamine in the striatum of MPTP-treated common marmosets: preliminary observations. J. Neural. Trans. Park Dis. Dement. Sect. 3 (1991) 73-78
15. Morris M.C., Evans D.A., Tangney C.C., Bienias J.L., Wilson R.S., Aggarwal N.T., and Scherr P.A. Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change. Am. J. Clin. Nutr. 81 (2005) 508-514
16. Nagatsu T. Amine-related neurotoxins in Parkinson's disease past, present, and future. Neurotoxicol. Teratol. 24 (2002) 565-569
17. Olanow C.W. Dietary Vitamin E and Parkinson's disease: something to chew on. Lancet Neurol. 2 (2003) 74
18. O'Leary K.A., Pascual-Tereasa S., Needs P.W., Bao Y.P., O'Brien N.M., and Williamson G. Effect of flavonoids and Vitamin E on cylcooxygenase-2 (COX-2) transcription. Mutat. Res. 551 (2004) 245-254
19. Park S.W., Kim S.H., Park K.H., Kim S.D., Kim J.Y., Baek S.Y., Chung B.S., and Kang C.D. Preventive effect of antioxidants in MPTP-induced mouse model of Parkinson's disease. Neurosci. Lett. 363 (2004) 243-246
20. Perry T.L., Yong V.W., Hansen S., Jones K., Bergeron C., Foulks J.G., and Wright J.M. Alpha-tocopherol and beta-carotene do not protect marmosets against the dopaminergic neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J. Neurol. Sci. 81 (1987) 321-331
21. Przedborski S., Tieu K., Perier C., and Vila M. MPTP as a mitochondrial neurotoxic model of Parkinson's disease. J. Bioenerg. Biomembr. 36 (2004) 375-379
22. Przybylkowski A., Kurkowska-Jastrzebska I., Joniec I., Ciesielska A., Czlonkowska A., and Czlonkowski A. Cyclooxygenases mRNA and protein expression in striata in the experimental mouse model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration to mouse. Brain Res. 1019 (2004) 144-151
23. Speciale S.G. Insights into parkinsonian neurodegeneration. Neurotoxicol. Teratol. 24 (2002) 607-620
24. Teismann P., Tieu K., Choi D.K., Wu D.C., Naini A., Hunot S., Vila M., Jackson-Lewis V., and Przedborski S. Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 5473-5478
25. Traber M.G., Siddens L.K., Leonard S.W., Schock B., Gohil K., Krueger S.K., Cross C.E., and Williams D.E. α-Tocopherol modulates Cyp3a expression, increases γ-CEHC production and limits tissue γ-tocopherol accumulation in mice fed high γ-tocopherol diets. Free Rad. Biol. Med. 38 (2005) 773-785
26. + induced COX-2 activation and subsequent dopaminergic neurodegeneration. FASEB J. 19 (2005) 1134-1136
27. Wu D., Liu L., Meydani M., and Meydani S.N. Vitamin E increases production of vasodilator prostanoids in human aortic endothelial cells through opposing effects on cyclooxygenase-2 and phospholipase A2. J. Nutr. 135 (2005) 1847-1853
28. Wu D.C., Teismann P., Tieu K., Vila M., Jackson-Lewis V., Ischiropoulos H., and Przedborski S. NADPH oxidase mediates oxidative stress in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Perkinson's disease. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 6145-6150
29. Yokota T., Igarashi K., Uchihara T., Jishage K., Tomita H., Inaba A., Li Y., Arita M., Suzuki H., Mizusawa H., and Arai H. Delayed-onset ataxia in mice lacking α-tocopherol transfer protein: model for neuronal degeneration caused by chronic oxidative stress. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 15185-15190
30. Zhang S.M., Hernan M.A., Chen H., Spiegelman D., Willett W.C., Ascherio A., et al. Intakes of Vitamins E and C, carotenoids, Vitamin supplements, and PD risk. Neurology 59 (2002) 1161-1169