A randomized controlled trial of increasing recombinant follicle-stimulating hormone after initiating a gonadotropin-releasing hormone antagonist for in vitro fertilization-embryo transfer

Fertility and Sterility

Volumn 86, Issue 1, 2006, Pages 58-63

  Propst, Anthony M ^a   Bates, G Wright ^a   Robinson, Randal D ^a   Arthur, Nancy J ^a   Martin, Joseph E ^b   Neal, Greg S ^b  

^a WILFORD HALL MEDICAL CENTER   (United States)

^b Hand Center of San Antonio   (United States)

Author keywords

estradiol; GnRH antagonist; IVF; pregnancy rate; recombinant FSH

Indexed keywords

CHORIONIC GONADOTROPIN; DESOGESTREL PLUS ETHINYLESTRADIOL; ESTRADIOL; FOLLITROPIN; GANIRELIX; GONADORELIN ANTAGONIST; ORAL CONTRACEPTIVE AGENT; RECOMBINANT FOLLITROPIN;

ADULT; ARTICLE; BODY MASS; CELL SIZE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE CALCULATION; EMBRYO; EMBRYO TRANSFER; ENDOMETRIUM CELL; ESTRADIOL BLOOD LEVEL; FEMALE; FEMALE INFERTILITY; FERTILIZATION IN VITRO; FOLLITROPIN BLOOD LEVEL; HORMONAL REGULATION; HORMONE INHIBITION; HUMAN; INTRACYTOPLASMIC SPERM INJECTION; MAJOR CLINICAL STUDY; MATERNAL AGE; MULTICENTER STUDY; NIDATION; OOCYTE DONATION; ORAL CONTRACEPTION; OUTCOME ASSESSMENT; OVARY FOLLICLE MATURATION; OVARY HYPERSTIMULATION; PREGNANCY OUTCOME; PREGNANCY RATE; PRIORITY JOURNAL; PRIVATE PRACTICE; PUBLIC HOSPITAL; RANDOMIZED CONTROLLED TRIAL;

DRUG ADMINISTRATION SCHEDULE; DRUG COMBINATIONS; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; FOLLICLE STIMULATING HORMONE; GONADOTROPIN-RELEASING HORMONE; HORMONE ANTAGONISTS; HUMANS; INCIDENCE; INFERTILITY, FEMALE; OVULATION INDUCTION; PILOT PROJECTS; PREGNANCY; PREGNANCY OUTCOME; PROSPECTIVE STUDIES; RECOMBINANT PROTEINS; TREATMENT OUTCOME;

EID: 33745491691     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2005.12.040     Document Type: Article

References (12)

1. The Ganirelix Dose-Finding Study Group. A double-blind, randomized, dose-finding study to assess the efficacy of the gonadotropin-releasing hormone antagonist Ganirelix to prevent premature luteinizing hormone surges in women undergoing ovarian stimulation with recombinant hormone. Hum Reprod 13 (1998) 3023-3031
2. Fluker M., Grifo J., Leader A., Levy M., Meldrum D., Muasher S.J., et al. The North American Ganirelix Study Group Efficacy and safety of ganirelix acetate versus leuprolide acetate in women undergoing controlled ovarian hyperstimulation. Fertil Steril 75 (2001) 38-45
3. Borm G., Mannaerts B., and The European Orgalutran Study Group. Treatment with the gonadotropin-releasing hormone antagonist ganirelix in women undergoing ovarian stimulation with recombinant follicle stimulating hormone is effective, safe and convenient. results of a controlled, randomized, multicentre trial. Hum Reprod 15 (2000) 1490-1498
4. Gordon K. Gonadotropin-releasing hormone antagonists. implications for oocyte quality and uterine receptivity. Ann NY Acad Sci 943 (2001) 49-54
5. Mansour R.T., Aboulghar M.A., Serour G.I., Al-Inany H.G., Amin Y.M., and Abou-Setta A.M. The use of gonadotropin-releasing hormone antagonist in a flexible protocol. a pilot study. Am J Obstet Gynecol 189 (2003) 444-446
6. Barmat L.I., Chantilis S.J., Hurst B.H., and Dickey R.P. A randomized prospective trial comparing gonadotropin-releasing hormone (GnRH) antagonist/recombinant follicle-stimulating hormone (rFSH) versus GnRH-agonist/rFSH in women pretreated with oral contraceptives before in vitro fertilization. Fertil Steril 83 (2005) 321-330
7. Akman M.A., Erden H.F., Tusun S.B., Bayazit N., Aksoy E., and Bahceci M. Comparison of agonistic flare-up protocol and antagonistic multiple dose protocol in ovarian stimulation of poor responders. results of a prospective randomized trial. Hum Reprod 16 (2001) 868-870
8. Retzloff M.G., Jackson K.V., Ashby R.K., Guarnaccia M.M., Ginsburg E.S., and Racowsky C. GnRH antagonists compares favorably, but is not superior, to GnRH agonist microflare for poor responders. Fertil Steril 80 (2003) S189
9. Copperman A.B., Sandler B., Mukherjee T., Grunfeld L., Bergh P., and Scott R.T. Optimizing stimulation protocols in IVF cycles using the GnRH antagonist. Fertil Steril 80 (2003) S96
10. Lindheim S.R., and Morales A.J. GnRH antagonists followed by a decline in serum estradiol results in adverse outcomes in donor oocyte cycles. Hum Reprod 18 (2003) 2048-2051
11. Acevedo B., Sanchez M., Gomez J.L., Cuadros J., Ricciarelli E., and Hernandez E.R. Luteinizing hormone supplementation increases pregnancy rates in gonadotropin-releasing hormone antagonist donor cycles. Fertil Steril 82 (2004) 343-347
12. Cédrin-Durnerin I., Grange-Dujardin D., Laffy A., Parneix I., Massin N., Galey J., et al. Recombinant human LH supplementation during GnRH antagonist administration in IVF/ICSI cycles. a prospective randomized study. Hum Reprod 19 (2004) 1979-1984