Protective effects of hirudin on acute experimental intracerebral hemorrhage

Zhongguo Zhongyao Zazhi

Volumn 31, Issue 1, 2006, Pages 69-72

  Zhang, Ying ^a   Feng, Jia Chun ^a   Wu, Jiang ^a   Ge, Ya Ping ^b   Zhang, Wei Hua ^a   Hu, Li Hua ^a   Han, Wei ^a  

^a THE FIRST HOSPITAL OF JILIN UNIVERSITY   (China)

^b Jilin Tumor Hospital   (China)

Author keywords

Glial fibrillary acidic protein; Hirudin; Intracerebral hemorrhage; Thrombin

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; HIRUDIN DERIVATIVE; NEUROPROTECTIVE AGENT;

ACUTE DISEASE; ANIMAL; ARTICLE; BRAIN; BRAIN HEMORRHAGE; FEMALE; MALE; METABOLISM; PATHOLOGY; RANDOMIZATION; RAT; WISTAR RAT;

ACUTE DISEASE; ANIMALS; BRAIN; CEREBRAL HEMORRHAGE; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; HIRUDINS; MALE; NEUROPROTECTIVE AGENTS; RANDOM ALLOCATION; RATS; RATS, WISTAR;

EID: 33745489132     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Peter D S, Olav J, Jochen B F, et al. Standardized MRI stroke protocol comparison with CT in hyperacute intracerebral hemorrhage. Stroke, 1999, 30: 765.
2. Wagner R H, Graham J B, Penick G D, et al. Estimation of prothrombin by the two-stage method, in tocantins LM, kazal LA (eds): blood coagulation, hemorrhage, and thrombosis, methods of study. New York: Grune & Stratton, 1955. 159.
3. Ayala Y, Cantwell A, Rose T, et al. Molecular mapping of thrombin receptor interactions. Proteins, 2001, 45(2): 107.
4. Chinese source
5. Holmin S, Scballing M, Hojeberg B, et al. Delayed cytokine expression in rat brain following experimental conclusion. J Neurosurg, 1997, 86(3): 493.
6. Kubo Y, Suzuki M, Kudo A, et al. Thrombin inhibitor ameliorates secondary damage in rat brain injury: suppression of inflammatory cells and vimentin-positive astrocytes. J Neurotrauma, 2000, 17 (2): 163.
7. Markwardt F. The development of hirudin as an antithrombotic drug. Thromb Res, 1994, 74(1): 1.
8. Chinese source
9. Fenton J W, Villanueva G B, Ofosu FA, et al. Thrombin inhibition by hirudin: how hirudin inhibits thrombin. Haemost, 1991, 21 (1): 27.
10. Oller T, Hanisch U K, Ransom B R. Thrombin-induced activation of cultured rodent microglia. J Neurochem, 2000, 75(4): 1539.