No clastogenic activity of Caesalpinia ferrea Mart. (Leguminosae) extract on bone marrow cells of Wistar rats

Genetics and Molecular Biology

Volumn 29, Issue 2, 2006, Pages 380-383

  de Souza, Andréa Bêcco ^a   Souza, Lilian Mara Silva ^a   Carvalho, José Carlos Tavares ^a   Maistro, Edson Luis ^a  

^a Universidade Jose do Rosario Vellano   (Brazil)

Author keywords

Caesalpinia ferrea; Chromosome aberrations; Micronucleus test

Indexed keywords

CAESALPINIA FERREA EXTRACT; CLASTOGEN; PLANT MEDICINAL PRODUCT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; BONE MARROW CELL; CAESALPINIA; CAESALPINIA FERREA; CHROMOSOME ABERRATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG CYTOTOXICITY; ERYTHROCYTE COUNT; FEEDING; FRUIT; LEGUME; MICRONUCLEUS; MITOSIS INDEX; NONHUMAN; RAT; RAT STRAIN; STATISTICAL SIGNIFICANCE; TOXICITY TESTING;

ANIMALIA; CAESALPINIA FERREA; FABACEAE; RATTUS NORVEGICUS;

EID: 33745483486     PISSN: 14154757     EISSN: 16784685     Source Type: Journal    
DOI: 10.1590/S1415-47572006000200028     Document Type: Article

References (13)

1. Alzugaray D (1984) Plantas que Curam. Hemus Press, Sõ Paulo.
2. Bacchi EM and Sertie JAA (1988) Ação anti-úlcera de Styrax camporum Pohl and Caesalpinia ferrea Mart. Tenth Brazilian Symposium in Medicinal Plants. São Paulo, pp 619.
3. Balbach A (1972) As Plantas que Curam. Três Press, São Paulo, pp 302-303.
4. a ediçõ. Três Press, São Paulo, pp 45-46.
5. Carvalho JCT (1993) Caesalpinia ferro (Pau-Ferro): Avaliaçõ da atividade antiinflamatória e analgésica. Masters Thesis. Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, 125 pp.
6. Carvalho JCT, Teixeira JRM, Souza PJC, Bastos JK, Santos-Filho D and Sarti SJ (1996) Preliminary studies of analgesic and anti-inflamatory properties of Caesalpinia ferrea crude extract. J Ethnopharmacol 53:175-178
7. Ford CE and Hamerton JL (1956) A colchicine, hypotonic citrate, squash sequence for mammalian chromosomes. Stain Technol 31:247-251.
8. Nakamura ES, Kurosaki F, Arisawa M, Mukainaka T, Okuda M, Tokuda H, Nishino H and Pastore F (2002a) Cancer chemo-preventive effects of constituents of Caesalpinia ferrea and related compounds. Cancer Lett 177:119-124.
9. Nakamura ES, Kurosaki F, Arisawa M, Mukainaka T, Takayasu J, Okuda M, Tokuda H, Nishino H and Pastore F (2002b) Cancer chemopreventive effects of a Brazilian folk medicine, Juca, on in vivo two stage skin carcinogenesis. J Ethnopharmacol 81:135-137.
10. Queiroz ML, Justo GZ, Valadares MC and Pereira-da-Silva FR (2001) Evaluation of Caesalpinia ferrea extract on bone marrow hematopoiesis in the murine models of listeriosis and Ehrlich ascites tumor. Immunopharmacol Immunotoxicol 23:367-382.
11. Schmid W (1976) The micronucleous test for cytogenetic analysis. In: Hollaender A. (ed) Chemical Mutagenesis, Principles and Methods for their Detection. v. 4. Plenum Press, New York, pp 31-53.
12. Surh Y and Ferguson LR (2003) Dietary and medicinal anti-mutagens and anticarcinogens: Molecular mechanisms and chemopreventive potential - highlights of a symposium. Mutat Res 523-524:1-8.
13. Thomas G, Araújo CC and Souza OS (1988) Avaliação das atividades anfiinflamatória, analgésica e antipirética dos extratos aquosos de Caesalpinia ferrea, Plantago major, Polygonum acre e Pterodon polygaeflorus. Tenth Brazilian Symposium in Medicinal Plants. São Paulo, Brasil, pp 619.