Rapid and efficient differentiation of dopaminergic neurons from mouse embryonic stem cells

NeuroReport

Volumn 17, Issue 10, 2006, Pages 975-979

  Lau, Thorsten ^a   Adam, Sylvia ^a   Schloss, Patrick ^a  

^a CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

Author keywords

Dopaminergic neurons; Embryonic stem cells; Neuronal differentiation

Indexed keywords

ASCORBIC ACID; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 8B; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CELL SELECTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; EMBRYO; EMBRYONIC STEM CELL; IMMUNOFLUORESCENCE; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; DOPAMINE; EMBRYO; FLOW CYTOMETRY; GROWTH SUBSTANCES; IMMUNOHISTOCHEMISTRY; MICE; NERVE TISSUE PROTEINS; NEURONS; STEM CELLS;

EID: 33745473077     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.wnr.0000223395.66951.01     Document Type: Article

References (25)

1. Evans MJ, Kaufman MH. Establishment in culture of pluripotent cells from mouse embryos. Nature 1981; 292:154-156.
2. McKay RDG. The origins of cellular diversity in the mammalian central nervous system. Cell 1989; 58:815-821.
3. Wobus AM, Boheler KR. Embryonic stem cells as developmental model in vitro. Cells Tissues Organs 1999; 165:129-130.
4. Bain G, Kitchens D, Yao M, Huettner JE, Gottlieb DI. Embryonic stem cells express neuronal properties in vitro. Dev Biol 1995; 168:342-357.
5. Okabe S, Forsberg-Nilsson K, Spiro AC, Segal M, McKay RDG. Development of neuronal precursor cells and functional post-mitotic neurons from embryonic stem cells in vitro. Mech Dev 1996; 59:89-102.
6. Lee SH, Lumelsky N, Studer L, Auerbach JM, McKay RDG. Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells. Nat Biotechnol 2000; 18:675-679.
7. Rolletschek A, Chang H, Guan K, Czyz J, Meyer M, Wobus AM. Differentiation of embryonic stem cell-derived dopaminergic neurons is enhanced by survival-promoting factors. Mech Dev 2001; 105:93-104.
8. Kawasaki H, Mizuseki K, Nishikawa S, Kaneko S, Kuwana Y, Nakanishi S, et al. Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron 2000; 28:31-40.
9. Morizane A, Takahashi J, Tagaky Y, Sasai Y, Hashimoto N. Optimal conditions for in vivo induction of dopaminergic neurons from embryonic stem cells through stromal cell-derived inducing activity. J Neurosci Res 2002; 69:934-939.
10. Nagy A, Rossant J, Nagy R, Abramov-Newerly W, Roder JC. Derivation of completely cell culture-derived mice from early passage embryonic stem cells. Proc Natl Acad Sci USA 1993; 90:8424-8428.
11. Nakayama T, Momoki-Saga T, Yamaguchi K, Inoue N. Efficient production of neuronal stem cells and neurons from embryonic stem cells. NeuroReport 2004; 153:487-491.
12. Santa-Ollala J, Covarrubias L. Epidermal growth factor (EGF), transforming growth factor-α (TGF-α), and basic fibroblast growth factor (bFGF) differentially influence neuronal precursor cells of mouse embryonic encephalon. J Neurosci Res 1995; 42:172-178.
13. Vicario-Abejon C, Johe KK, Hazel TG, Collazo D, McKay RDG. Function of basic fibroblast growth factor and neurotrophins in the differentiation of hippocampal neurons. Neuron 1995; 15:105-114.
14. Yan J, Struder L, McKay RDG. Ascorbic acid increases the yield of dopaminergic neurons derived from basic fibroblast growth factor expanded mesencephalic precursors. J Neurochem 2001; 76:307-311.
15. Bibel M, Richter J, Schrenk K, Tucker KL, Staiger V, Korte M, et al. Differentiation of mouse embryonic stem cells into a defined neuronal lineage. Nat Neurosci 2004; 79:1003-1009.
16. Gritti A, Cova L, Parati EA, Galli R, Vescovi AL. Basic fibroblast growth factor supports the proliferation of epidermal growth factor-generated neuronal precursor cells of the adult mouse CNS. Neurosci Lett 1995; 185:151-154.
17. Suter-Crazzolara C, Unsicker K. GDNF mRNA levels are induced by FGF-2 in rat C6 glioblastoma cells. Mol Brain Res 1996; 41:175-182.
18. Reynolds BA, Weiss S. Clonal and population analysis demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell. Dev Biol 1996; 175:1-13.
19. Jessell M. Neuronal specification in the spinal cord: inductive signals and transcription codes. Nat Rev Genet 2000; 1:20-29.
20. Hynes M, Rosenthal A. Specification of dopaminergic and serotonergic neurons in the vertebrate CNS. Curr Opin Neurobiol 1999; 9:26-36.
21. Ye W, Shimamura K, Rubenstein JL, Hynes MA, Rosenthal A. FGF and SHH signals control dopaminergic and serotonergic cell fate in the anterior neuronal plate. Cell 1998; 93:755-766.
22. Simeone A. Genetic control of dopaminergic neuron differentiation. Trends Neurosci 2005; 238:62-65.
23. Chung S, Sonntag KC, Andersson T, Bjorklund LM, Park JJ, Kim DW, et al. Genetic engineering of mouse embryonic stem cells by Nurr1 enhances differentiation and maturation into dopaminergic neurons. Eur J Neurosci 2002; 16:1829-1838.
24. Andersson E, Tryggvason U, Deng Q, Friling S, Alekseenko Z, Robert B, et al. Identification of intrinsic determinants of midbrain dopamine neurons. Cell 2006; 124:393-405.
25. Salli U, Reddy AP, Salli N, Lu NZ, Kuo HC, Pau FKY, et al. Serotonin neurons derived from rhesus monkey embryonic stem cells: similarities to CNS serotonin neurons. Exp Neurol 2004; 188:351-364.