A community-based epidemiologic study of gender differences in the relationship between insulin resistance/β-cell dysfunction and diabetic retinopathy among type 2 diabetic patients in Kinmen, Taiwan

Ophthalmologica

Volumn 220, Issue 4, 2006, Pages 252-258

  Liu, Jorn Hon ^a,d   Tung, Tao Hsin ^a   Tsai, Shih Tzer ^b   Chou, Pesus ^a   Chuang, Shao Yuan ^a   Chen, Shih Jen ^a,b   Lee, Fenq Lih ^b   Shih, Hui Chuan ^c   Li, Wen Ling ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^c KAOHSIUNG ARMED FORCES GENERAL HOSPITAL   (Taiwan)

^d CHENG HSIN REHABILITATION MEDICAL CENTER   (Taiwan)

Author keywords

cell dysfunction; Diabetic retinopathy; Insulin resistance; Type 2 diabetes

Indexed keywords

ADULT; AGED; CONFERENCE PAPER; DIABETIC RETINOPATHY; FEMALE; GENDER; HUMAN; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OPHTHALMOSCOPY; PANCREAS ISLET BETA CELL; RISK FACTOR; SCREENING TEST; TAIWAN;

ADULT; DIABETES MELLITUS, TYPE 2; DIABETIC RETINOPATHY; FEMALE; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; MALE; PILOT PROJECTS; POPULATION SURVEILLANCE; RETROSPECTIVE STUDIES; SEX FACTORS; TAIWAN;

EID: 33745466892     PISSN: 00303755     EISSN: None     Source Type: Journal    
DOI: 10.1159/000093080     Document Type: Conference Paper

References (28)

1. Ciulla TA, Amador AG, Ziman B: Diabetic retinopathy and diabetic macular edema. Diabetes Care 2003;26:2653-2664.
2. Kohner EM, Aldington SJ, Stratton IM, et al: United Kingdom Prospective Diabetes Study, 30: diabetic retinopathy at diagnosis of non-insulin-dependent diabetes mellitus and associated risk factors. Arch Ophthalmol 1998;116:297-303.
3. Dowse GK, Humphrey AR, Collins VR, et al: Prevalence and risk factors for diabetic retinopathy in the multiethnic population of Mauritius. Am J Epidemiol 1998;147:448-457.
4. Haddad OA, Saad MK: Prevalence and risk factors for diabetic retinopathy among Omani diabetics. Br J Ophthalmol 1998;82:901-906.
5. Klein R, Klein BEK, Moss SE, Davis MD, DeMets DL: The Wisconsin epidemiologic study of diabetic retinopathy. 3. Prevalence and risk of diabetic retinopathy when age at diagnosis is 30 or more years. Arch Ophthalmol 1984;102:527-532.
6. UK Prospective Diabetes Study Group: Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. BMJ 1998;317:703-713.
7. Chen MS, Kao CS, Fu CC, Chen CJ, Tai TY: Prevalence and risk factors of diabetic retinopathy among non-insulin-dependent diabetic subjects. Am J Ophthalmol 1992;114:723-730.
8. LeRoith D: Beta-cell dysfunction and insulin resistance in type 2 diabetes: role of metabolic and genetic abnormalities. Am J Med 2002;113(suppl 6A):3S-11S.
9. Wallace TM, Matthews DR: The assessment of insulin resistance in man. Diabetes Med 2002;19:527-534.
10. Ferrannini E: Insulin resistance versus insulin deficiency in non-insulin-dependent diabetes mellitus. Problems and prospects. Endocr Rev 1998;19:477-490.
11. Haffner SM, D'Agostino RB, Saad MF, et al: Increased insulin resistance and insulin secretion in nondiabetic African-Americans and Hispanics compared with non-Hispanic whites - The Insulin Resistance Atherosclerosis Study. Diabetes 1996;45:742-748.
12. Li CL, Tsai ST, Chou P: Relative role of insulin resistance and β-cell dysfunction in the progression to type 2 diabetes - The Kinmen Study. Diabetes Res Clin Pract 2003;59:225-232.
13. Suzuki K, Watanabe K, Motegi T, Kajinuma H: High prevalence of proliferative retinopathy in diabetic patients with low pancreatic β-cell capacity. Diabetes Res Clin Pract 1989;6:45-52.
14. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF: Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28:412-419.
15. Chou P, Liao MJ, Kuo HS, Hsiao KJ, Tsai ST: A population survey on the prevalence of diabetes in Kin-Hu, Kinmen. Diabetes Care 1994;17:1055-1058.
16. World Health Organization: Definition, Diagnosis and Classification of Diabetes Mellitus and Its Complications: Report of a WHO Consultation. 1. Diagnosis and Classification of Diabetes Mellitus. Geneva, World Health Organization, 1999.
17. Emoto M, Nishizawa Y, Maekawa K, et al: Homeostasis model assessment as a clinical index of insulin resistance in type 2 diabetic patients treated with sulfonylureas. Diabetes Care 1999;157:836-848.
18. Bonora E, Targher G, Alberiche M, et al: Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity. Studies in subjects with various degrees of glucose tolerance and insulin sensitivity. Diabetes Care 2000;23:57-63.
19. Wilkinson CP, Ferris FL 3rd, Klein RE, et al: Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales. Ophthalmology 2003;110:1677-1682.
20. Katsumori K, Wasada T, Kuroki H, et al: Prevalence of macro- and microvascular diseases in non-insulin-dependent diabetic and borderline glucose-intolerant subjects with insulin resistance syndrome. Diabetes Res Clin Pract 1995;29:195-201.
21. Maneschi F, Mashiter K, Kohner EM: Insulin resistance and insulin deficiency in diabetic retinopathy of non-insulin-dependent diabetes. Diabetes 1983;32:82-87.
22. Madsbad S, Lauritzen E, Faber OK, Binder C: The effect of residual beta-cell function on the development of diabetic retinopathy. Diabet Med 1986;3:42-45.
23. Kuusisto J, Lempiainen P, Mykkanen L, Laakso M: Insulin resistance syndrome predicts coronary heart disease events in elderly type 2 diabetic men. Diabetes Care 2001;24:1629-1633.
24. Pyorala M, Miettinen H, Halonen P, Laakso M, Pyorala K: Insulin resistance syndrome predicts the risk of coronary heart disease and stroke in healthy middle-aged men: the 22-year follow-up results of the Helsinki Policemen Study. Arterioscler Thromb Vasc Biol 2000;20:538-544.
25. Lempiainen P, Mykkanen L, Pyorala K, Laakso M, Kuusisto J: Insulin resistance syndrome predicts coronary heart disease events in elderly nondiabetic men. Circulation 1999;100:123-128.
26. Schiffrin A, Suissa S, Weitzner G, Poussier P, Lalla D: Factors predicting course of β-cell function in IDDM. Diabetes Care 1992;15:997-1001.
27. Livingstone C, Collison M: Sex steroids and insulin resistance. Clin Sci 2002;102:151-166.
28. Ciulla TA, Amador AG, Zinman B: Diabetic retinopathy and diabetic macular edema: pathophysiology, screening, and novel therapies. Diabetes Care 2003;26:2653-2664.