Hydrolysis of α-alkyl-α-(methylthio)methylene Meldrum's acids. A kinetic and computational investigation of steric effects

Journal of Organic Chemistry

Volumn 71, Issue 13, 2006, Pages 4795-4802

  Bernasconi, Claude F ^a   Brown, Shoshana D ^a   Ali, Mahammad ^a,d   Rappoport, Zvi ^b   Yamataka, Hiroshi ^c   Salim, Hatim ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c RIKKYO UNIVERSITY   (Japan)

^d JADAVPUR UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

METHYLENE MELDRUM'S ACIDS; STERIC CROWDING; STERIC EFFECTS; TETRAHEDRAL INTERMEDIATES;

CARBON CARBON COMPOSITES; CHEMICAL BONDS; COMPUTATIONAL METHODS; HYDROLYSIS; PH EFFECTS; SOLUTIONS; SUBSTRATES;

ORGANIC ACIDS;

ACETIC ACID; ACID; ALPHA (METHYLTHIO)METHYLENE MELDRUM ACID; BASE; BUFFER; DIMETHYL SULFOXIDE; ETHYL GROUP; FUNCTIONAL GROUP; HYDROGEN; HYDROXYL GROUP; MELDRUM ACID; METHYL GROUP; S BUTYL GROUP; TERT BUTYL GROUP; UNCLASSIFIED DRUG; WATER;

ADDITION REACTION; ARTICLE; CHEMICAL REACTION KINETICS; CHEMOREACTIVITY; COVALENT BOND; DOUBLE BOND; HYDROLYSIS; MATHEMATICAL ANALYSIS; PH; REACTION ANALYSIS; STEREOCHEMISTRY;

COMPUTER SIMULATION; DIMETHYL SULFOXIDE; DIOXANES; HYDROLYSIS; KINETICS; MODELS, CHEMICAL; MOLECULAR STRUCTURE; STEREOISOMERISM; WATER;

EID: 33745454255     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo060254o     Document Type: Article

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