Selection of resistance mutations in children receiving prophylaxis with lamivudine or nevirapine for the prevention of postnatal transmission of HIV [3]

Journal of Acquired Immune Deficiency Syndromes

Volumn 42, Issue 1, 2006, Pages 131-133

  Giuliano, Marina ^a   Galluzzo, Clementina M ^a   Germinario, Elena A P ^a   Amici, Roberta ^a   Bassani, Luciana ^a   Dehò, Lorenzo ^b   Vyankandondera, Joseph ^c   Mmiro, Francis ^d   Okong, Pius ^e   Vella, Stefano ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c Centre Hospitalier Universitaire de Kigali   (Rwanda)

^d MULAGO HOSPITAL   (Uganda)

^e St Francis Hospital Uganda   (Uganda)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; LAMIVUDINE; NEVIRAPINE; RNA DIRECTED DNA POLYMERASE INHIBITOR; VIRUS RNA;

CHILD; GENE MUTATION; GENETIC RESISTANCE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFANT; INFECTION PREVENTION; LETTER; MAJOR CLINICAL STUDY; MOTHER CHILD RELATION; POSTNATAL CARE; PRIORITY JOURNAL; RISK ASSESSMENT; VIRUS RESISTANCE; VIRUS TRANSMISSION;

DISEASE TRANSMISSION, VERTICAL; DRUG RESISTANCE, VIRAL; FEMALE; HIV INFECTIONS; HIV PROTEASE; HIV-1; HUMANS; INFANT; INFANT, NEWBORN; LAMIVUDINE; MUTATION; NEVIRAPINE; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; REVERSE TRANSCRIPTASE INHIBITORS; RNA-DIRECTED DNA POLYMERASE; RWANDA; SELECTION (GENETICS); SPECIES SPECIFICITY; TREATMENT OUTCOME; UGANDA;

EID: 33745447241     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.qai.0000209911.10071.18     Document Type: Letter

References (7)

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2. Jourdain G, Ngo-Giang-Huong N, Le Coeur S, et al. Intrapartum exposure to nevirapine and subsequent maternal responses to nevirapine-based antiretroviral therapy. N Engl J Med. 2004;351:229-240.
3. Vyankandondera J, Luchters S, Hassink E, et al. Reducing risk of HIV-1 transmission from mother to infant through breastfeeding using antiretroviral prophylaxis in infants (SIMBA study) [abstract # LB7]. Paper presented at: the 2nd IAS Conference on HIV Pathogenesis and Treatment; 2003; Paris, France.
4. Martinson N, Morris L, Gray G, et al. HIV resistance and transmission following single-dose nevirapine in a PMTCT cohort [abstract # 38]. Paper presented at: the 11th Conference on Retroviruses and Opportunistic Infections; 2004; San Francisco, CA.
5. Collins JA, Thompson M, Alexande L. Competitive fitness of HIV-1 mutations that confer resistance to nevirapine [abstract # H-811]. Paper presented at: the 43rd ICAAC; 2003; Chicago, IL.
6. Mandelbrot L, Landreau-Mascaro A, Rekacewicz C, et al. Lamivudine-zidovudine combination for prevention of maternal-infant transmission of HIV-1. JAMA. 2001;285:2083-2093.
7. Verhofstede C, Van Wanzeele F, Van Der Gucht B, et al. Interruption of reverse transcriptase inhibitors or a switch from reverse transcriptase to protease inhibitors resulted in a fast reappearance of virus strains with a reverse transcriptase inhibitor-sensitive genotype. AIDS. 1999;13:2541-2546.