Clinically relevant drug interaction between voriconazole and tacrolimus in a primary renal allograft recipient [2]

Transplantation

Volumn 81, Issue 12, 2006, Pages 1750-1752

  Kuypers, Dirk R ^a   Claes, Kathleen ^a   Evenepoel, Pieter ^a   Vanrenterghem, Yves ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; CALCINEURIN INHIBITOR; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; TACROLIMUS; VORICONAZOLE;

AGED; AREA UNDER THE CURVE; ASPERGILLOSIS; CASE REPORT; DRUG DOSE REDUCTION; DRUG METABOLISM; GRAFT REJECTION; HUMAN; KIDNEY ALLOGRAFT; LETTER; MALE; PNEUMONIA; PRIORITY JOURNAL;

AGED; DRUG INTERACTIONS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION; PYRIMIDINES; TACROLIMUS; TRANSPLANTATION, HOMOLOGOUS; TRIAZOLES;

EID: 33745435960     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.tp.0000226080.71764.8c     Document Type: Letter

References (6)

1. Jeu L, Piacenti FJ, Lyakhovetskiy AG, Fung HB. Voriconazole Clin Ther 2003; 25: 1321.
2. Venkataramanan R, Zang S, Gayowski T, Singh N. Voriconazole inhibition of the metabolism of tacrolimus in a liver transplant recipient and in human liver micosomes. Antimicrob Agents Chemother 2002; 46: 3091.
3. Tintillier M, Kirch L, Goffin E, et al. Interaction between voriconazole and tacrolimus in a kidney-transplanted patient. Nephrol Dial Transplant 2005; 20: 665.
4. Pai M, Allen S. Voriconazole inhibition of tacrolimus metabolism. Clin Infect Dis 2003; 36: 1089.
5. Vfend (Voriconazole) [package insert]. New York: Pfizer; 2002.
6. Floren LC, Bekersky I, Benet LZ, et al. Tacrolimus oral bioavailability doubles with coadministration of ketoconazole. Clin Pharmacol Ther 1997; 62: 41.