Expression of p53 in virally infected tubular cells in renal transplant patients with polyomavirus nephropathy

Human Pathology

Volumn 37, Issue 6, 2006, Pages 684-688

  Weinreb, David B ^a   Desman, Garrett T ^a   Burstein, David E ^a   Kim, Dae Un ^b   Dikman, Steven H ^a   Johnson, Edward M ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b SAINT BARNABAS MEDICAL CENTER   (United States)

Author keywords

Immunohistochemistry; Kidney; Nephropathy; p53; Polyoma; T antigen

Indexed keywords

PROTEIN P53; VIRUS T ANTIGEN;

ARTICLE; BLADDER BIOPSY; BLADDER MUCOSA; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY GRAFT; KIDNEY INFECTION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN STABILITY; VIRUS INFECTION;

ANTIGENS, VIRAL, TUMOR; BIOPSY; HUMANS; KIDNEY TRANSPLANTATION; KIDNEY TUBULES; POLYOMAVIRUS; POLYOMAVIRUS INFECTIONS; TRANSPLANTATION, HOMOLOGOUS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33745434046     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2006.01.016     Document Type: Article

References (15)

1. Bollag B., Chuke W.F., and Frisque R.J. Hybrid genomes of the polyomaviruses JC virus, BK virus, and simian virus 40: identification of sequences important for efficient transformation. J Virol 63 (1989) 863-872
2. Harris K.F., Chang E., Christensen J.B., and Imperiale M.J. BK virus as a potential co-factor in human cancer. Dev Biol Stand 94 (1998) 81-91
3. DeCaprio J.A., Ludlow J.W., Figge J., et al. SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell 54 (1988) 275-283
4. Reich N.C., and Levine A.J. Specific interaction of the SV40 T antigen-cellular p53 protein complex with SV40 DNA. Virology 117 (1982) 286-290
5. Krynska B., Otte J., Franks R., Khalili K., and Croul S. Human ubiquitous JCV(CY) T-antigen gene induces brain tumors in experimental animals. Oncogene 18 (1999) 39-46
6. Dyson N., Bernards R., Friend S.H., et al. Large T-antigens of many polyomaviruses are able to form complexes with the retinoblastoma protein. J Virol 64 (1990) 1353-1356
7. Berger J.R. Progressive multifocal leukoencephalopathy. Curr Treat Options Neurol 2 (2000) 361-368
8. Seth P., Diaz F., and Major E.O. Advances in the biology of JC virus and induction of PML. J Neurovirol 9 (2003) 236-246
9. Hirsch H.H. BK virus: opportunity makes a pathogen. Clin Infect Dis 41 (2005) 354-360
10. Khalili K., Del Valle L., Otte J., Weaver M., and Gordon J. Human neurotropic polyomavirus, JCV, and its role in carcinogenesis. Oncogene 22 (2003) 5181-5191
11. Weinreb D.B., Desman G.T., Amolat-Apiado M.J., Burstein D.E., Godbold Jr. J.H., and Johnson E.M. Polyoma virus infection is a prominent risk factor for bladder carcinoma in immunocompetent individuals. Diagn Cytopathol 34 (2006) 201-203
12. Geetha D., Tong B.C., Racusen L., Markowitz J.S., and Westra W.H. Bladder carcinoma in a transplant recipient: evidence to implicate the BK human polyomavirus as a causal transforming agent. Transplantation 73 (2002) 1933-1936
13. Reihsaus E., Kohler M., Kraiss S., Oren M., and Montenarh M. Regulation of the level of the oncoprotein p53 in non-transformed and transformed cells. Oncogene 5 (1990) 137-145
14. Mann R.S., and Carroll R.B. Cross-reaction of BK virus large T antigen with monoclonal antibodies directed against SV40 large T antigen. Virology 138 (1984) 379-385
15. Pipas J.M., and Levine A.J. Role of T antigen interactions with p53 in tumorigenesis. Semin Cancer Biol 11 (2001) 23-30