Upregulation of P2Y2 nucleotide receptors in rat salivary gland cells during short-term culture

American Journal of Physiology

Volumn 273, Issue 3 PART 1, 1997, Pages

  Turner, John T ^a   Weisman, Gary A ^a   Camden, Jean M ^a  

^a University of Missouri   (United States)

Author keywords

Extracellular nucleotides; P2y2 receptor expression; Parotid gland; Receptor regulation; Sublingual gland; Submandibular gland

Indexed keywords

EID: 33745380378     PISSN: 00029513     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Amsallem, H., M. Métioui, A. VandenAbeele, A. Elyamani, A. Moran, and J.-P. Dehaye. Presence of a metabotropic and an ionotropic purinergic receptor on rat submandibular ductal cells. Am. J. Physiol. 271 (CellPhysiol. 40): C1546-C1555, 1996.
2. Boarder, M. R., G. A. Weisman, J. T. Turner, and G. F. Wilkinson. G protein-coupled PZ purinoceptors: from molecular biology to functional responses. Trends Pharmacol. Sei. 16: 133-139, 1995.
3. Buell, G., C. Lewis, G. Collo, R. A. North, and A. Surprenant. An antagonist-insensitive ?2x receptor expressed in epithelia and brain. EMBO J. 15: 55-62, 1996.
4. Burnstock, G., and B. F. King. Numbering of cloned P2 purinoceptors. DrugDev. Res. 38: 67-71, 1996.
5. Chang, K., K. Hanaoka, M. Kumada, and Y. Takuwa. Molecular cloning and functional analysis of a novel P% nucleotide receptor. J. Biol. Chem. 270: 26152-26158, 1995.
6. Chiozzi, P., M. Murgia, S. Falzoni, D. Ferrari, and F. Di Virgilio. Role of the purinergic ?2z receptor in spontaneous cell death in J774 macrophage cultures. Biochem. Biophys. Res. Commun. 218: 176-181, 1996.
7. Commun!, D., S. Pirotton, M. Parmentier, and J.-M. Boeynaenis. Cloning and functional expression of a human uridine nucleotide receptor. J. Biol. Chem. 270: 3Q849-30852, 1995.
8. Dehaye, J. P., and R. J. Turner. Isolation and characterization of rat submandibular intralobular ducts. Am. J. Physiol. 261 (Cell Physiol. 30): C490-C496, 1991.
9. Dubyak, G. R., and C. El-Moatassim. Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides. Am. J. Physiol. 265 (Cell Physiol. 34): C577-C606, 1993.
10. Erb, L., R. Garrad, Y. Wang, T. Quinn, J. T. Turner, and G. A. Weisman. Site-directed mutagenesis of P2u purinoceptors: positively charged amino acids in transmembrane helices 6 and 7 affect agonist potency and specificity. J. Biol. Chem. 270: 4185-4188, 1995.
11. Erb, L., K. D. Lustig, D. M. Sullivan, J. T. Turner, and G. A. Weisman. Functional expression and photoaffinity labeling of a cloned P2u purinergic receptor. Proc. Natl. Acad. Sei. USA 90: 10449-10453, 1993.
12. Filippini, A., R. E. Taffs, T. Agui, and M. V. Sitkovsky. Ecto-ATPase activity in cytolytic T-lymphocytes: protection from the cytolytic effects of extracellular ATP. J. Biol. Chem. 265: 334-340, 1990.
13. Firestein, B. L., M. Z. Xing, R. J. Hughes, C. U. Corvera, and P. A. Insel. Heterogeneity of P2U- and P2y-purinergic receptor regulation of phospholipases in MDCK cells. Am. J. Physiol. 271 (Renal Fluid Electrolyte Physiol. 40): F610-F618, 1996.
14. Gallacher, D. V. Are there purinergic receptors on parotid acinar cells? Nature 296: 83-86, 1982.
15. 2+ in the mouse submandibular salivary cell line STgss- Br. J. Pharmacol. Ill: 1135-1139, 1994.
16. Grynkiewicz, G., M. Poenie, and R. Y. Tsien. A new generation of Ca24 indicators with greatly improved fluorescence properties. J. Biol. Chem. 260: 3440-3450, 1985.
17. Harden, T. K., J. L. Boyer, and R. A. Nicholas. P2-purinergic receptors: subtype-associated signaling responses and structure. Annu. Rev. Pharmacol. Toxicol. 35: 541-579, 1995.
18. Hoey, E. D., M. Nicol, B. C. Williams, and S. W. Walker. Primary cultures of bovine inner zone adrenocortical cells secrete Cortisol in response to adenosine triphosphate, adenosine diphosphate, and uridine triphosphate via a nucleotide receptor which may be coupled to two signal generation systems. Endocrinology 134: 1553-1560, 1994.
19. Humphreys-Beher, M. G. Control of cell growth and proliferation. In: Biology of the Salivary Glands, edited by K. DobrosielskiVergona. Boca Raton, FL: CRC, 1993, p. 239-262.
20. Knowles, M. R., L. L. Clarke, and R. C. Boucher. Activation by extracellular nucleotides of chloride secretion in the airway epithelia of patients with cystic fibrosis. N. Engl. J. Med. 325: 533-538, 1991.
21. Koshiba, M., S. Apasov, V. Sverdlov, P. Chen, L. Erb, J. T. Turner, G. A. Weisman, and M. V. Sitkovsky. Transient up-regulation of P2Y2 nucleotide receptor mRNA expression is an immediate early gene response in activated thymocytes. Proc. Natl. Acad. Sei. USA 94: 831-836, 1997.
22. Lustig, K. D., A. K. Shiau, A. J. Brake, and D. Julius. Expression cloning of an ATP receptor from mouse neuroblastoma cells. Proc. Natl. Acad. Sei. USA 90: 5113-5117, 1993.
23. Mahmoud, M. S. W., P. Wang, S. R. Hootman, S. S. Reich, and I. H. Chaudry. Downregulation of hepatocyte P2-purinoceptor binding capacity after trauma-hemorrhage/resuscitation. Am. J. Physiol. 266 (Regulatory Integrative Comp. Physiol. 35): R1804-R1809, 1994.
24. Martin, K. A., S. B. Kertesy, and G. R. Dubyak. Downregulation of P2u-purinergic nucleotide receptor messenger RNA expression during in vitro differentiation of human myeloid leukocytes by phorbol esters or inflammatory activators. Mol. Pharmacol. 51: 97-108, 1997.
25. Martinez, J. R., D. B. Bylund, and N. Cassity. Progressive secretory dysfunction in the rat submandibular gland after excretory duct ligation. Arch. Oral Biol. 27: 443-450, 1982.
26. McMillian, M. K., S. P. Soltoff, L. C. Cantley, and B. R. Talamo. Extracellular ATP elevates intracellular free calcium in rat parotid acinar cells. Biochem. Biophys. Res. Commun. 149: 523-530, 1987.
27. Nguyen, T., L. Erb, G. A. Weisman, A. Marchese, H. H. Q. Heng, R. C. Garrad, S. R. George, J. T. Turner, and B. F. O'Dowd. Cloning, expression and chromosomal localization of the human uridine nucleotide receptor. J. Biol. Chem. 270: 30845-30848, 1995.
28. 2 receptors: identification of a UDP-selective, a UTP-selective, and an ATP- and UTP-specific receptor. Mol. Pharmacol. 50: 224-229, 1996.
29. 2+\ via different P2-receptor subtypes in freshly isolated and cultured aortic myocytes. Am. J. Physiol. 269 (Heart Circ. Physiol. 38): H30-H36, 1995.
30. Paradiso, A. M., S. J. Mason, E. R. Lazarowski, and R. C. Boucher. Membrane-restricted regulation of Ca2" release and influx in polarized epithelia. Nature 377: 643-646, 1995.
31. Park, M., J. M. Camden, G. A. Weisman, and J. T. Turner. Development-related changes in P2 purinoceptor functionality and mRNA abundance in salivary gland cells (Abstract). FASEB J. 9:A118, 1995.
32. Park, M., J. M. Camden, G. A. Weisman, and J. T. Turner. Developmental aspects of salivary gland P2-purinoceptor expression and function (Abstract). J. Dent. Res. 75: 251, 1996.
33. Park, M., R. C. Garrad, G. A. Weisman, and J. T. Turner. Changes in P2Yi nucleotide receptor activity during the development of rat salivary glands. Am. J. Physiol. 272 (Cell, Physiol. 41): C1388-C1393, 1997.
34. Parr, C. E., D. M. Sullivan, A. M. Paradiso, E. R. Lazarowski, L. H. Burch, J. C. Olsen, L. Erb, G. A. Weisman, R. C. Boucher, and J. T. Turner. Cloning and expression of a human P2u nucleotide receptor, a target for cystic fibrosis pharmacotherapy. Proc. Natl. Acad. Sei. USA 91: 3275-3279, 1994.
35. Quissell, D. O., K. B. Barzen, D. C. Gruenert, R. S. Redman, J. M. Camden, and J. T. Turner. Development and characterization of immortalized rat submandibular acinar cell lines using an origin-defective SV40 plasmid. In Vitro Cell. Dev. Biol. 33: 164-173, 1997.
36. Rice, W. R., F. M. Burton, and D. T. Fiedeldey. Cloning and expression of the alveolar type II cell P2u-purinergic receptor. Am. J. Respir. Cell Mol. Biol. 12: 27-32, 1995.
37. Soltoff, S. P., M. K. McMillian, E. J. Cragoe, L. C. Cantley, and B. R. Talamo. Effects of extracellular ATP on ion transport systems and |Ca2]j in rat parotid acinar cells. J. Gen. Physiol. 95: 319-346, 1990.
38. Soltoff, S. P., M. K. McMillian, and B. R. Talamo. ATP activates a cation-permeable pathway in rat parotid acinar cells. Am. J. Physiol. 262 (Cell Physiol. 31): C934-C940, 1992.
39. Surprenant, A., F. Rassendren, E. Kawashima, R. A. North, and G. Buell. The cytolytic P2z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science 272: 735-738, 1996.
40. Tsukahara, T., Y. Yonekawa, M. Yamamoto, Y. Kaku, N. Ogata, and T. Taniguchi. Regeneration of the rat carotid artery after clipping injury. Part II. A pharmacological study. Neurosurgery 32: 73-78, 1993.
41. Turner, J. T., and J. M. Camden. The influence of vasoactive intestinal peptide receptors in dispersed acini from rat submandibular gland on cyclic AMP production and mucin release. Arch. Oral BioL 35: 103-108, 1990.
42. Turner, J. T., D. M. Sullivan, I. Rovira, and J. M. Camden. A regulatory role for 5-hydroxytryptamine receptors positively coupled to adenylyl cyclase in mammalian submandibular salivary glands. J. Dent. Res. 75: 935-941, 1996.
43. 2+ signalling receptors in the rat submandibular salivary gland ducts. J. Physiol. (Lond.) 491: 647-662, 1996.
44. Yu, H., and J. T. Turner. Functional studies in the human submandibular duct cell line, HSG-PA, suggest a second salivary gland receptor subtype for nucleotides. J. Pharmacol. Exp. Ther. 259: 1344-1350, 1991.
45. Yu, S.-M., S.-F. Chen, Y.-T. Lau, C.-M. Yang, and J.-C. Chen. Mechanism of extracellular ATP-induced proliferation of vascular smooth muscle cells. Mol. Pharmacol. 50: 1000-1009, 1996.
46. Zegarra-Moran, O., G. Romeo, and L. J. V. Galietta. Regulation of transepithelial ion transport by two different purinoceptors in the apical membrane of canine kidney (MDCK) cells. Br. J. Pharmacol. 114: 1052-1056, 1995.