Narcolepsy-cataplexy associated with precocious puberty

Neurology

Volumn 66, Issue 10, 2006, Pages 1577-1579

  Plazzi, G ^a   Parmeggiani, A ^a   Mignot, E ^b   Lin, L ^b   Scano, M C ^a   Posar, A ^a   Bernardi, F ^a   Lodi, R ^a   Tonon, C ^a   Barbiroli, B ^a   Montagna, P ^a   Cicognani, A ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLONAZEPAM; HLA DQB1 ANTIGEN; LAMOTRIGINE; METHYLPREDNISOLONE; MODAFINIL; VALPROIC ACID; VENLAFAXINE; ASPARTIC ACID; BENZHYDRYL DERIVATIVE; CREATINE; CYCLOHEXANOL DERIVATIVE; DRUG DERIVATIVE; N ACETYLASPARTIC ACID; N-ACETYLASPARTATE; NEUROPEPTIDE; OREXINS; SIGNAL PEPTIDE;

ARTICLE; AUDITORY HALLUCINATION; BODY MASS; CASE REPORT; CATAPLEXY; CLINICAL FEATURE; DAYTIME SOMNOLENCE; DIAGNOSTIC IMAGING; DISEASE ASSOCIATION; DISEASE SEVERITY; DRUG TREATMENT FAILURE; FEMALE; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; MALE; NARCOLEPSY; NIGHTMARE; OBESITY; POLYSOMNOGRAPHY; PRECOCIOUS PUBERTY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SCHOOL CHILD; SKIN BIOPSY; SYMPTOM; VISUAL HALLUCINATION; CHEMISTRY; CHILD; HALLUCINATION; HEALTH EDUCATION; HYPOTHALAMUS; PATHOPHYSIOLOGY; PHYSIOLOGY; SOMNOLENCE; TELEVISION;

ASPARTIC ACID; BENZHYDRYL COMPOUNDS; CATAPLEXY; CHILD; CREATINE; CYCLOHEXANOLS; DISORDERS OF EXCESSIVE SOMNOLENCE; FEMALE; HALLUCINATIONS; HEALTH EDUCATION; HUMANS; HYPOTHALAMUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; NARCOLEPSY; NEUROPEPTIDES; NIGHT TERRORS; OBESITY; POLYSOMNOGRAPHY; PUBERTY, PRECOCIOUS; TELEVISION;

EID: 33745360679     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.wnl.0000216142.21375.71     Document Type: Article

References (10)

1. American Academy of Sleep Medicine. International classification of sleep disorders. 2nd ed. Diagnostic and coding manual. Westchester, IL: American Academy of Sleep Medicine; 2005.
2. Ferguson AV, Samson WK. The orexin/hypocretin system: a critical regulator of neuroendocrine and autonomic function. Front Neuroendocrinol 2003;24:141-150.
3. Kotagal S, Krahn LE, Slocumb N. A putative link between childhood narcolepsy and obesity. Sleep Med 2004;5:147-150.
4. Russell SH, Small CJ, Dakin CL, et al. Effects of orexins on the hypothalamic-pituitary-adrenal system. J Neuroendocrinol 2000;12:1174-1178.
5. Chisholm RC, Brook CJ, Harrison GF, Lyon L, Zukaitis D. Prepubescent narcolepsy in a six year old girl. Sleep Res 1985;15:113. Abstract.
6. Boris NW, Hagino OR, Steiner GP. Case study: hypersomnolence and precocious puberty in a child with pica and chronic lead intoxication. J Am Acad Child Adolesc Psychiatry 1996;35:1050-1054.
7. Lodi R, Tonon C, Vignatelli L, et al. In vivo evidence of neuronal loss in the hypothalamus of narcoleptic patients. Neurology 2004;63:1513-1515.
8. Kohsaka A, Watanobe H, Kakizaki Y, Suda T, Schioth HB. A significant participation of orexin-A, a potent orexigenic peptide, in the preovulatory luteinizing hormone and prolactin surges in the rat. Brain Res 2001;898:166-170.
9. Kok SW, Roelfsema F, Overeem S, et al. Altered setting of the pituitary-thyroid ensemble in hypocretin-deficient narcoleptic men. Am J Physiol Endocrinol Metab 2005;288:E892-E899.
10. Laron Z. Is obesity associated with early sexual maturation? Pediatrics 2004;113:171-172.