Glutathione supplements protect preterm rabbits from oxidative lung injury

American Journal of Physiology

Volumn 270, Issue 3 PART 1, 1996, Pages

  Brown, Lou Ann S ^a,b   Ferez, Jose A ^a,b   Harris, Frank L ^a,b   Clark, Reese H ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Dept of Pediatrics ^*  (United States)

Author keywords

Hyperoxia in vivo; Lung compliance; Lung mechanics

Indexed keywords

EID: 33745349408     PISSN: 00029513     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Aw, T. Y., G. Wierzbicka, and D. P. Jones. Oral glutathione increases tissue glutathione in vivo. Chem.-Biol. Int. 80: 89-97, 1991.
2. Bai, C., L. A. S. Brown, and D. P. Jones. Transport of glutathione from the vasculature to the alveolar type II cell. Am. J. PhvKiot. 267 (Lung Cell. Mol. Physiol. Il): L447-L455. 1994.
3. Bradford, M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Bioehem. 72: 248-254, 1976.
4. Brown, L. A. S. Glutathione protects signal transduction in type II cells under oxidant stress. Am. J. Phvsiol. 266 (Lung Cell. Mol. Phvsiol. 10): L172-L177, 1994.
5. Brown, L. A. S., C. Bai, and D. P. Jones. Glutathione protection in alveolar type II cells from fetal and neonatal rabbits. Am. J. Phvsiol. 262 (Lung CM. Mol. Phyaiol. 6): L305-L312. 1992.
6. Brown, L. A. S., J. A. Perez, and R. H. Clark. Protection from oxidative injury by glutathione (GSH) in a preterm rabbit model (Abstract). Pediatr. Res. 33: 318A, 1993.
7. Buhl, R., C. Vogelmeier, M. Crittenden, R. C. Hubbard, R. F. Hoyt, E. M. Wilson, A. M. Cantin, and R. G. Crystal. Augmentation of glutathione in the fluid lining the epithelium of the lower respiratory tract by directly administering glutathione aerosol. Proc. Natl. Acad. Sei. USA 87: 4063-4067, 1990.
8. Cantin, A. M., R. C. Hubbard, and R. G. Crystal. Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis. Am. Rev. Respir. Dis. 139: 370-372, 1989.
9. Coalson, J. J., T. J. Kuehl, T. J. Prihoda, and R. A. deLemos. Diffuse alveolar damage in the evolution of bronchopulmonary dysplasia in the baboon. Pediatr. Ren. 24: 357-366, 1988. 10. Deneke, S. M., and B. L. Fanburg. Regulation of cellular glutathione. Am. J. Phvsiol. 257 (Lung CM. Mot. Phvsiol. 1): L163-L173. 1989.
10. Farrell, P. M., and R. H. Perelman. The respiratory system: part 1). In: Behrman's Neonatal-Perinatal Medicine: Diseases of the Fetus and Newborn, edited by A. A. Fanaroff and R. J. Martin. St. Louis, MO: Mosby, 1983, p. 53-80.
11. Frank, L. Antioxidants, nutrition, and bronchopulmonary dysplasia. Clin. Perinatal. 19: 541-562, 1992.
12. Frank, L., and I. R. S. Sosenko. Prenatal development of lung antioxidant enzymes in four species. J. Pediatr. 110: 106-110. 1987.
13. Grigg, J., A. Barber, and M. Silverman. Bronehoalveolar lavage fluid glutathione in intubated premature infants. Arch. Dis. Child 69: 49-51, 1993.
14. Hagen, T. M., L. A. S. Brown, and D. P. Jones. Protection against paraquat-induced injury by exogenous GSH in pulmonary alveolar type II cells. Biochem. Pharmacol. 35: 4537-4542, 1986.
15. Heffner, J. E., and J. E. Repine. Pulmonary strategies of antioxidant defense. Am. Reu. Respir. Dis. 140: 531-554, 1989.
16. Jackson, R. M. Molecular, pharmacologie and clinical aspects of oxygen-induced lung injury. Clin. Chest Med. 11: 73-83, 1990.
17. Meredith, K. S., R. A. deLemos, J. J. Coalson, R. J. King, D. R. Gerstmann, R. Kumar, T. J. Kuehl, D. C. Winter, A. Taylor, R. H. Clark, and D. M. Null. Role of lung injury in the pathogenesis of hyaline membrane disease in premature baboons. J. Appl. Physiol. 66: 2150-2158, 1989.
18. Obrodovich, H. M., and R. B. Mellins. Bronchopulmonary dysplasia. Am. Rev. Respir. Dis. 132: 694-709, 1985.
19. Patterson, C. E., J. A. Butler, F. D. Byrne, and M. L. Rhoades. Oxidant lung injury: intervention with sulfhydryl reagents. Lung 163: 23-32, 1985.
20. Reed, D. J., J. R. Babson, P. W. Beatty, A. E. Brodle, W. W. Ellis, and D. W. Potter. High performance liquid chromatography analysis of nanomole levels of glutathione, glutathione disulfide and related thiols and disulfides. Anal. Biochem. 72: 55-62, 1980.
21. Rennard, S. I., G Basset, D. Lecossier, K. M. O'Donnell, P. Pinkston, P. G. Martin, and R. G. Crystal. Estimation of volume of epithelial lining fluid recovered by lavage using urea as a marker of dilution. J. Appl. Physiol. 60: 532-538, 1986.
22. Skipski, V. M., M. Barclay, E. S. Reichman, and J. J. Good. Separation of acidic phospholipids by one-dimensional thin-layer chromatography. Biochem. Biophyx. Ac ta 137: 80-89, 1967.
23. Smith, L. J., J. Anderson, and M. Shamsuddin. Glutathione localization and distribution after intratracheal instillation. Implication for treatment. Am. Rev. Respir. Dis. 145: 153-159, 1992.
24. Smith, C. V. T. N. Hansen, N. E. Martin, H. W. McMicken, and S. J. Elliott. Oxidant stress responses in premature infants during exposure to hyperoxia. Pediatr. Res. 34: 360-365, 1993.
25. Tsai, M. Y., M. Cain, and M. W. Josephson. Improved thin layer chromatography of disaturated phosphatidylcholine in amniotic fluid. Clin. Chem. 27: 239-242, 1981.
26. Weber, C. A., C. A. Duncan, M. J. Lyons, and S. G. Jenkinson. Depletion of tissue glutathione with diethyl maleate enhances hyperbaric oxygen toxicity. Am. J. Physiol. 258 (Lung Cell. Mol. Physiol. 2): L308-L312, 1990.