System design and development of a pinhole SPECT system for quantitative functional imaging of small animals

Annals of Nuclear Medicine

Volumn 20, Issue 3, 2006, Pages 245-251

  Aoi, Toshiyuki ^a,b   Zeniya, Tsutomu ^a   Watabe, Hiroshi ^a   Deloar, Hossain M ^a   Matsuda, Tetsuya ^b   Iida, Hidehiro ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Complete data acquisition; Pinhole SPECT; Small animal imaging

Indexed keywords

OXIDRONATE TECHNETIUM TC 99M;

ALGORITHM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAMERA; COLLIMATOR; COMPUTER PROGRAM; COMPUTER SYSTEM; CONTROLLED STUDY; DIAGNOSTIC IMAGING; IMAGE RECONSTRUCTION; MEDICAL INSTRUMENTATION; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; RAT; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

ANIMALS; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; IMAGE ENHANCEMENT; PHANTOMS, IMAGING; POSITRON-EMISSION TOMOGRAPHY; RATS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 33745294128     PISSN: 09147187     EISSN: 09147187     Source Type: Journal    
DOI: 10.1007/BF03027438     Document Type: Article

References (25)

1. Chatziioannou AF. PET scanner dedicated to molecular imaging of small animal models. Mol Imaging Biol 2002; 4: 47-63.
2. Tai YC, Chatziioannou AF, Yang Y, Silverman RW, Meadors K, Siegle S, et al. MicroPET II: design, development and initial performance of an improved microPET scanner for small-animal imaging. Phys Med Biol 2003; 48: 1519-1537.
3. Jeavons AP, Chandler RA, Dettmar CAR. A 3D HIDAC-PET camera with submillimetre resolution for imaging small animals. IEEE Trans Nucl Sci 1999; 46: 468-473.
4. Weber DA, Ivanovic M, Franceschi D, Strand S-E, Erlandsson K, Franceschi M, et al. Pinhole SPECT: An approach to in vivo high resolution SPECT imaging in small laboratory animals. J Nucl Med 1994; 35: 342-348.
5. Jaszczak RJ, Li J, Wang H, Zalutsky MR, Coleman RE. Pinhole collimation for ultra-high-resolution small-field-of-view SPECT. Phys Med Biol 1994; 39: 425-437.
6. Ishizu, K, Mukai T, Yonekura Y, Pagani M, Fujita T, Magata Y, et al. Ultra-high resolution SPECT system using four pinhole collimators for small animal studies. J Nucl Med 1995; 36: 2282-2287.
7. Ogawa K, Kawade T, Nakamura K, Kubo A, Ichihara T. Ultra high resolution SPECT for small animal study. IEEE Trans Nucl Sci 1998; 45: 3122-3126.
8. Aoi T, Watabe T, Deloar HM, Ogawa M, Teramoto N, Kudomi N, et al. Absolute quantitation of regional myocardial blood flow of rats using dynamic pinhole SPECT. Conference Record of IEEE Nuclear Science and Medical Imaging Conference 2002.
9. Feldkamp LA, Davis LC, Kress JW. Practical cone beam algorithm. J Opt Soc Am 1984: 29: 612-619.
10. Shepp LA, Vardi Y. Maximum likelihood reconstruction for emission tomography. IEEE Trans Med Imag 1982; MI-1: 113-122.
11. Lange K, Carson R. EM reconstruction algorithms for emission and transmission tomography. J Comput Assist Tomogr 1984; 8: 306-316.
12. Hudson HM, Larkin RS. Accelerated image reconstruction using ordered subsets of projection data. IEEE Trans Med Imag 1994; 13: 601-609.
13. Vanhove C, Defrise M, Franken PR, Everaert H, Deconinck F, Bossuyt A. Interest of the ordered subsets expectation maximization (OS-EM) algorithm in pinhole single-photon emission tomography reconstruction: a phantom study. Eur J Nucl Med 2000; 27: 140-146.
14. Tuy HK. An inversion formula for cone-beam reconstruction. SIAM J Appl Math 1983; 43: 546-552.
15. Grangeat O, Sire P, Guillemaud R, La V. Indirect conebeam three-dimensional image reconstruction. In: Contemporary Perspectives in Three-Dimensional Biomedical Imaging, Roux C, Coatrieux JL (eds), Amsterdam; IOS Press, 1997: 29-52, 343-350.
16. Kudo H, Saito T. Feasible cone beam scanning methods for exact reconstruction in three-dimensional tomography. J Opt Soc Am A 1990; 7: 2169-2181.
17. Kudo H, Saito T. Derivation and implementation of a conebeam reconstruction algorithm for nonplanar orbits. IEEE Trans Med Imag 1994; 13: 196-211.
18. Kudo H, Saito T. An extended completeness condition for exact cone-beam reconstruction and its application. Conference Record of IEEE Nuclear Science and Medical Imaging Conference 1994, 1710-1714.
19. Zeniya T, Watabe H, Aoi T, Kim KM, Teramoto N, Hayashi T, et al. A new reconstruction strategy for image improvement in pinhole SPECT. Eur J Nucl Med Mol Imag 2004; 31: 1166-1172.
20. Li J, Jaszczak RJ, Greer KL, Coleman RE. A filtered backprojection algorithm for pinhole SPECT with a displaced center-of-rotation. Phys Med Biol 1994; 39: 165-176.
21. Li J, Jaszczak RJ, Coleman RE. Maximum likelihood reconstruction for pinhole SPECT with a displaced centerof-rotation. IEEE Trans Med Imag 1995; 14: 407-409.
22. Habraken JB, de Bruin K, Shehata M, Booij J, Bennink R, van Eck Smit BL, et al. Evaluation of high-resolution pinhole SPECT using a small rotating animal. J Nucl Med 2001; 42: 1863-1869.
23. Metzler SD, Greer KL, Jaszczak RJ. Helical pinhole SPECT for small-animal imaging: A method for addressing sampling completeness. IEEE Trans Nucl Sci 2003; 50: 1575-1583.
24. Deloar HM, Watabe H, Aoi T, Iida H. Evaluation of penetration and scattering components in conventional pinhole SPECT: phantom studies using Monte Carlo simulation. Phys Med Biol 2003; 48: 1-14.
25. Smith MF, Jaszczak RJ. The effect of gamma ray penetration on angle-dependent sensitivity for pinhole collimation in nuclear medicine. Med Phys 1997; 24: 1701-1709.