Arterial wall cholesterol content is a predictor of development and severity of arterial thrombosis

Journal of Thrombosis and Thrombolysis

Volumn 22, Issue 1, 2006, Pages 5-11

  Ma, Hongbao ^a   Aziz, Kusai S ^a   Huang, Ruiping ^a   Abela, George S ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Atherosclerosis; Cholesterol; Thrombosis; Vulnerable plaque

Indexed keywords

CHOLESTEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY THROMBOSIS; ARTERY WALL; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE COURSE; DISEASE SEVERITY; ELECTRON MICROSCOPY; HISTOPATHOLOGY; MALE; NONHUMAN; PREDICTOR VARIABLE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RABBIT; STATISTICAL SIGNIFICANCE; THROMBOGENESIS;

ANIMALS; AORTA; ATHEROSCLEROSIS; CHOLESTEROL; DIET, ATHEROGENIC; ENDOTHELIUM, VASCULAR; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; MODELS, ANIMAL; RABBITS; THROMBOSIS;

EID: 33745281217     PISSN: 09295305     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11239-006-7861-x     Document Type: Article

References (40)

1. Abela GS, Picon PD, Friedl SE, et al (1995) Triggering of plaque disruption and arterial thrombosis in an atherosclerotic rabbit model. Circulation 91:776-784
2. Constantinides P, Chakravarti RN (1961) Rabbit arterial thrombosis production by systemic procedures. Arch Pathol 72:197-208
3. Christov A, Dai E, Drangova M, et al (2000) Optical detection of triggered atherosclerotic plaque disruption by fluorescence emission analysis. J Photochem Photobiol 72:242-252
4. Johnstone MT, Botnar RM, Perez AS, et al (2000) In vivo magnetic resonance imaging of experimental thrombosis in a rabbit model. Thromb Vasc Biol 21:1556-1560
5. Davies MJ, Thomas AC (1985) Plaque fissuring: The cause of acute myocardial infarction causing sudden ischaemic death, and crecendo angina. Br Heart J 53:363-373
6. Muller JE, Abela GS, Nesto RW, Tofler GH (1994) Triggers, acute risk factors, and vulnerable plaques: The lexicon of a new frontier. J Am Coll Cardiol 23:809-813
7. Libby P (1995) Molecular bases of the acute coronary syndrome. Circulation 91:2844-2850
8. Lendon CL, Davies MJ, Born GVR, Richardson PD (1991) Atherosclerotic plaque caps are locally weakened when macrophages density is increased. Atherosclerosis 87:87-90
9. Davies MJ, Richardson PD, Woolf N, Katz DR, Mann J (1993) Risk of thrombosis in human atherosclerotic plaques: Role of extracellular lipid, marcrophage, and smooth muscle cell content. Br Heart J 69:377-381
10. Li H, Cybulsky MI, Gimbrone MA, Libby P (1993) An atherogenic diet rapidly induces VCAM-1, a cytokine-regulatable mononuclear leukocyte adhesion molecule, in rabbit aortic endothelium. Arterioscler Thromb 13:197-204
11. Aikawa M, Voglic SJ, Sugiyama S, et al (1999) Dietary lipid lowering reduces tissue factor expression in rabbit atheroma. Circulation 100:1215-1222
12. Loree HM, Kamm RD, Stringfellow RG, Lee RT (1992) Effects of fibrous cap thickness on peak circumferential stess in model atheroscelrotic vessels. Circ Res 71:850-858
13. Castelli WP, Anderson K, Wilson PW, Levy D (1992) Lipids and risk of coronary heart disease. The Framingham Study. Ann Epidemiol 2:23-28
14. The Multiple risk factor intervention trial (MRFIT) (1976) A national study of primary prevention of coronary heart disease. JAMA 235:825-827
15. Goldstein JA, Demetriou D, Grines CL, Pica M, Shoukfeh M, O'Neill WW (2000) Multiple complex coronary plaques in patients with acute myocardial infarction. N Eng J Med 343:915-922
16. Qiao JH, Fisbein MC (1991) The severity of coronary atherosclerosis at sites of plaque rupture with occlusive thrombosis. J Am Coll Card 17:1138-1142
17. Thompson PD, Moyna NM, White CM, Weber KM, Giri S, Waters DD (2002) The effects of hydroxy-methyl-glutaryl co-enzyme A reductase inbhibitors on platelet thrombus formation. Atherosclerosis 16:301-306
18. Dangas G, Badimon JJ, Smith DA, et al (1999) Pravastatin therapy in hyperlipidemia: Effects on thrombus formation and the systemic hemostatic profile. J Am Coll Cardiol 33:1294-1304
19. Kim JC, Chung TH (1984) Direct determination of free cholesterol and individual cholesterol esters in serum by high pressure liquid chromatography. Korean J Biochem 16:69-77
20. Little WC, Constanitinescu M, Applegate RJ, et al (1988) Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mid-to-moderate coronary artery disease? Circulation 78:1157-1166
21. Ueda Y, Asakura M, Hirayama A, Komamura K, Hori M, Kodama K (1996) Intracoronary morphology of culprit lesions after reperfusion in acute myocardial infarction: Serial angioscopic observations. J Am Coll Cardiol 27:606-610
22. Salonen JT, Salonen R (1991) Ultrasonographically assessed carotid morphology and the risk of coronary heart disease. Arterioscler Thromb 11:1245-1249
23. Mittleman MA, Maclure M, Tofler GH, Sherwood JB, Goldberg RJ, Muller JE (1993) Triggering of acute myocardial infarction by heavy physical exertion. Protection against triggering by regular exertion. N Engl J Med 329:1677-1683
24. Tofler GH, Stone PH, Maclure M, et al (1990) Analysis of possible triggers of acute myocardial infarction. Am J Cardiol 66:22-27
25. Tofler GH, Brezinski D, Schafer AI, et al (1987) Concurrent morning increase in platelet aggregability and the risk of myocardial infarction and sudden cardiac death. N Eng J Med 316:1514-1518
26. Sagel J, Colwell JA, Crook L, Laimins M (1975) Increased platelet aggregation in early diabetes mellitus. Ann Int Med 82:733-738
27. Shepherd J, Cobbe SM, Ford I, et al (1995) for the West of Scotland Coronary Prevention Study Group. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N Eng J Med 333:1301-1307
28. The Scandinavian Survival Study Group (1994) Randomized trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Survival Study (4S). Lancet 344:1383-1389
29. Staprans I, Pan XM, Rapp JH, Feingold KR (1998) Oxidized cholesterol in the diet accelerates the development of aortic atherosclerosis in cholesterol-fed rabbits. Arterioscler Thromb Vasc Biol 18:977-983
30. Ridker PM, Cannon CP, Morrow D, et al (2005) C-Reactive protein levels and outcomes after statin therapy. N Engl J Med 352:20-28
31. Nissen SE, Tuzcu EM, Schoenhagen, et al (2005) Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease. N Engl J Med 352:29-38
32. Lacoste L, Lam JY, Hung J, Letchacovski G, Solymoss CB, Waters D (1997) Hyperlipidemia and coronary disease. Correction of the increased thrombogenic potential with cholesterol reduction. Circulation 96:2097-2099
33. Toschi V, Gallo R, Lettino M, et al (1997) Tissue factor modulates the thrombogenicity of human atherosclerotic plaques. Circulation 95:594-599
34. Maier W, Altwegg LA, Corti R, et al (2005) Inflammatory markers at the site of ruptured plaque in acute myocardial infarction. Circulation 111:1355-1361
35. Virk IS, Claycombe K, Ma H, et al (2004) Rising Levels of CRP and PAI-1 After Plaque Disruption Are Associated with Thrombosis. Circulation (abstr) 110:1486
36. Danenberg HD, Szalai AJ, Swaminathan RV, et al (2003) Increased thrombosis after arterial injury in human C-reactive protein-transgenic mice. Circulation 108:512-515
37. Burke GL, Evans GW, Riley WA, et al (1995) Arterial wall thickness is associated with prevalent cardiovascular disease in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study. Stroke 26:386-391
38. Abela GS, Aziz K (2005) Cholesterol crystals cause mechanical damage to biological membranes: A proposed mechanism of plaque rupture and erosion leading to arterial thrombosis. Clin Card 28:413-420
39. Abela GS, Aziz K (2006) Cholesterol crystals rupture biological membranes and human plaques during acute cardiovascular events: A novel insight into plaque rupture by scanning electron microscopy. Scanning 28:1-10
40. Abela GS, Eisenberg JD, Mittleman M, et al (1999) Detecting and differentiating white from red coronary thrombus by angiography in angina pectoris and in acute myocardial infarction. Am J Card 83:94-97