Update on hypothesis linking chloroquine-resistant malaria to disease-causing HIV

Medical Hypotheses

Volumn 67, Issue 3, 2006, Pages 670-671

  Parris, George E ^a  

^a NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROQUINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BCL 2; PROTEIN BCL XL;

APOPTOSIS; BYSTANDER EFFECT; DRUG TARGETING; HOST CELL; HOST PATHOGEN INTERACTION; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNOREGULATION; INFECTION RESISTANCE; LETTER; MALARIA; NONHUMAN; PRIORITY JOURNAL; VIRUS INFECTIVITY; VIRUS VIRULENCE;

ANTIMALARIALS; CHLOROQUINE; DRUG RESISTANCE; HIV; HIV INFECTIONS; HUMANS; MALARIA; MODELS, BIOLOGICAL;

EID: 33745279607     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2006.04.016     Document Type: Letter

References (6)

1. Parris G.E. Hypothesis links emergence of chloroquine-resistant malaria and other intracellular pathogens and suggests a new strategy for treatment of diseases caused by intracellular parasites. Med Hypotheses 62 (2004) 354-357
2. Dobbelaere D.A., and Kuenzi P. The strategies of the Theileria parasite: a new twist in host-pathogen interactions. Curr Opin Immunol 16 (2004) 524-530
3. Bierhaus A., Hemmer C.J., Mackman N., et al. Antiparasitic treatment of patients with P. falciparum malaria reduces the ability of patient serum to induce tissue factor by decreasing NF-κ B activation. Thromb Haemost 73 (1995) 39-48
4. Guillemard E., Jacquemot C., Aillet F., Schmitt N., Barre-Sinoussi F., and Israel N. Human immunodeficiency virus 1 favors the persistence of infection by activating macrophages through TNF. Virology 329 (2004) 371-380
5. Moon H.S., and Yang J.S. Role of HIV Vpr as a regulator of apoptosis and an effector on bystander cells. Mol Cells 21 (2006) 7-20
6. Petrovas C., Mueller Y.M., Dimitriou I.D., et al. HIV-specific CD8+ T cells exhibit markedly reduced levels of Bcl-2 and Bcl-xL. J Immunol 172 (2004) 4444-4453