Differences in methylation patterns in the methylation boundary region of IDS gene in hunter syndrome patients: Implications for CpG hot spot mutations

European Journal of Human Genetics

Volumn 14, Issue 7, 2006, Pages 838-845

  Tomatsu, Shunji ^a   Sukegawa, Kazuko ^b   Trandafirescu, Georgeta G ^a   Gutierrez, Monica A ^a   Nishioka, Tatsuo ^a   Yamaguchi, Seiji ^c   Orii, Tadao ^b   Froissart, Roseline ^d   Maire, Irene ^d   Chabas, Amparo ^e   Cooper, Alan ^f   Di Natale, Paola ^g   Gal, Andreas ^h   Noguchi, Akihiko ^a   Sly, William S ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c SHIMANE UNIVERSITY   (Japan)

^d HÔPITAL DEBROUSSE   (France)

^e Institut de Bioquimica Clinica Barcelona   (Spain)

^f ROYAL MANCHESTER CHILDREN S HOSPITAL   (United Kingdom)

^g UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^h UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

CpG dinucleotide; IDS; Methylation; Mucopolysaccharidosis II; Recurrent mutation

Indexed keywords

BISULFITE; CYTOSINE DERIVATIVE; IDURONATE 2 SULFATASE;

ADOLESCENT; ADULT; ARTICLE; CHILD; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; CPG ISLAND; EXON; FETUS; GENE SEQUENCE; GENETIC DIFFERENCE; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; HUMAN; HUNTER SYNDROME; INTRON; MALE; MOLECULAR CLONING; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN METHYLATION; SEQUENCE ANALYSIS;

ADOLESCENT; ADULT; AMINO ACID SEQUENCE; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CPG ISLANDS; DNA METHYLATION; EXONS; GLYCOPROTEINS; HUMANS; INFANT; MALE; MOLECULAR SEQUENCE DATA; MUCOPOLYSACCHARIDOSIS II; POINT MUTATION; PROMOTER REGIONS (GENETICS); SEQUENCE ANALYSIS, DNA;

EID: 33745278108     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5201615     Document Type: Article

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