Virulence factors in enterococcal infections of orthopedic devices

International Journal of Artificial Organs

Volumn 29, Issue 4, 2006, Pages 402-406

  Baldassarri, Lucilla ^a   Creti, R ^a   Recchia, S ^a   Pataracchia, M ^a   Alfarone, G ^a   Orefici, G ^a   Campoccia, D ^b   Montanaro, L ^b,c   Arciola, Carla Renata ^b,c  

^a Higher Institute of Health   (Italy)

^b RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Biofilm; Enterococci; Gelatinase; Virulence

Indexed keywords

GENES;

BIOFILM FORMATION; ENTEROCOCCUS; ENTEROCOCCUS FAECALIS; GELATINASE; GENE CODING; NOSOCOMIAL INFECTION; ORTHOPAEDIC DEVICES; SURFACE PROTEINS; VIRULENCE; VIRULENCE FACTORS;

BIOFILMS;

GELATINASE; MEMBRANE PROTEIN;

ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; BACTERIUM ISOLATION; BIOFILM; CONTROLLED STUDY; CULTURE MEDIUM; DEVICE INFECTION; ENTEROCOCCAL INFECTION; ENTEROCOCCUS FAECALIS; GENETIC CODE; GENOTYPE; INFECTION RISK; NONHUMAN; OPPORTUNISTIC INFECTION; PHENOTYPE; POLYMERASE CHAIN REACTION; QUANTITATIVE ANALYSIS; RISK FACTOR; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

EID: 33745274814     PISSN: 03913988     EISSN: None     Source Type: Journal    
DOI: 10.1177/039139880602900410     Document Type: Article

References (20)

1. Murray BE, Weinstock GM. Enterococci: New aspects of an old organism. Proc Assoc Am Physicians 1999; 111: 328-34.
2. Bonten MJ, Willems R, Weinstein R. Vancomycin-resistant enterococci: Why are they here, and where do they come from? Lancet Infect Dis 2001; 1: 314-25.
3. Baldassarri L, Creti R, Montanaro L, Orefici L, Arciola CR. Pathogenesis of implant infections by enterococci. Int J Artif Organs 2005; 28: 1101-9.
4. Di Rosa R, Basoli A, Donelli G, Penni A, Salvatori FM, Fiocca F, Baldassarri L. A microbiological and morphological study of blocked biliary stents. Microb Ecol Health Dis 1999; 11: 84-8.
5. Baldassarri L, Cecchini R, Bertuccini L, Ammendolia MG, Iosi F, Arciola CR, Di Rosa R, Gherardi G, Dicuonzo G, Orefici G, Creti R. Enterococcus spp. produces slime and survives in rat peritoneal macrophages. Med Microbiol Immunol 2001; 190: 113-20.
6. Toledo-Arana A, Valle J, Solano C, Arrizubieta MJ, Cucarella C, Lamata M, Amorena B, Leiva J, Penades JR, Lasa I. The enterococcal surface protein, Esp, is involved in Enterococcus faecalis biofilm formation. Appl Environ Microbiol 2001; 67: 4538-45.
7. Coque TM, Patterson JE, Steckelberg JM, Murray BE. Incidence of hemolysin, gelatinase, and aggregation substance among enterococci isolated from patients with endocarditis and other infections and from feces of hospitalized and community-based persons. J Infect Dis 1995; 171: 1223-9.
8. Eaton TJ, Gasson MJ. Molecular screening of Enterococcus virulence determinants and potential for genetic exchange between food and medical isolates. Appl Environ Microbiol 2001; 67: 1628-35.
9. Waar K, Muscholl-Silberhorn AB, Willems RJ, Slooff MJ, Harmsen HJ, Degener JE. Genogrouping and incidence of virulence factors of Enterococcus faecalis in liver transplant patients differ from blood culture and fecal isolates. J Infect Dis 2002; 185: 1121-7.
10. Creti R, Imperi M, Bertuccini L, Fabretti F, Orefici G, Di Rosa R, Baldassarri L. Survey for virulence determinants among Enterococcus faecalis isolated from different sources. J Med Microbiol 2004; 53: 13-20.
11. Tendolkar PM, Baghdayan AS, Gilmore MS, Shankar N. Enterococcal surface protein Esp, enhances biofilm formation by Enterococcus faecalis. Infect Immun 2003; 72: 6032-9.
12. Hufnagel M, Koch S, Creti R, Baldassarri L, Huebner J. A putative sugar-binding transcriptional regulator in a novel gene locus in Enterococcus faecalis contributes to production of biofilm and prolonged bacteremia in mice. J Infect Dis 2004; 189: 420-30.
13. Kristich CJ, Li YH, Cvitkovitch DG, Dunny M. Esp-independent biofilm formation by Enterococcus faecalis. J Bacteriol 2003; 186: 154-63.
14. Mohamed JA, Huang W, Nallapareddy SR, Teng F, Murray BE. Influence of origin of isolates, especially endocarditis isolates, and various genes on biofilm formation by Enterococcus faecalis. Infect Immun 2004; 72: 3658-63.
15. Mohamed JA, Murray BE. Lack of correlation of gelatinase production and biofilm formation in a large collection of Enterococcus faecalis isolates. J Clin Microbiol 2005; 43: 5405-7.
16. Di Rosa R, Creti R, Venditti M, D'Amelio R, Arciola CR, Montanaro L, Baldassarri L. Relationship between biofilm formation, the enterococcal surface protein (Esp) and gelatinase in clinical isolates of Enterococcus faecalis and Enterococcus faecium. FEMS Microbiol Lett 2006; 256: 145-50.
17. Dicuonzo G, Gherardi G, Lorino G, Angeletti S, Battistoni F, Bertuccini L, Creti R, Di Rosa R, Venditti M, Baldassarri L. Antibiotic resistance and genotypic characterization of clinical and environmental isolates of enterococci. FEMS Microbiol Lett 2001; 201: 205-11.
18. Robert JC, Singh KV, Okhuysen PC, Murray BE. Molecular epidemiology of the fsr locus and gelatinase production among different subsets of Enterococcus faecalis isolates. J Clin Microbiol 2004; 42: 2317-20.
19. Gutschik E, Moller S, Christensen N. Experimental endocarditis in rabbits. Significance of the proteolytic capacity of the infecting strains of Streptococcus faecalis. Acta Pathol Microbiol Scand [B] 1979; 87: 353-62.
20. Baldassarri L, Creti R, Arciola CR, Montanaro L, Venditti M, Di Rosa R. Analysis of virulence factors in cases of enterococcal endocarditis. Clin Microbiol Infect 2004; 10: 1006-8.