The Role of Radiation Therapy in Locally Advanced Endometrial Cancer

Seminars in Radiation Oncology

Volumn 16, Issue 3, 2006, Pages 152-157

  Anderson, Penny R ^a  

^a FOX CHASE CANCER CENTER   (United States)

Author keywords

adjuvant therapy; locally advanced endometrial cancer; radiation therapy

Indexed keywords

ADVANCED CANCER; ARTICLE; CANCER ADJUVANT THERAPY; CANCER MORTALITY; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER RISK; CANCER SURGERY; DISEASE SEVERITY; ENDOMETRIUM CANCER; FEMALE; HUMAN; PAPILLARY CARCINOMA; PRIORITY JOURNAL; TREATMENT OUTCOME; UTERUS CARCINOMA;

ADENOCARCINOMA; ENDOMETRIAL NEOPLASMS; FEMALE; HUMANS; RADIOTHERAPY, ADJUVANT;

EID: 33745273592     PISSN: 10534296     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semradonc.2006.02.003     Document Type: Article

References (41)

1. Cancer Statistics 2005. CA Cancer J Clin 55 (2005) 10-30
2. Barnes M.N., and Kilgore L.C. Complete surgical staging of early endometrial adenocarcinoma. Optimizing patient outcomes. Semin Radiat Oncol 10 (2000) 3-7
3. Pustilnik T., and Burke T.W. Adjuvant chemotherapy for high-risk endometrial cancer. Semin Radiat Oncol 10 (2000) 23-28
4. Morrow C.P., Bundy B.N., Kurman R.J., et al. Relationship between surgical-pathological risk factors and outcome in clinical stage I and II carcinoma of the endometrium. A Gynecologic Oncology Group study. Gynecol Oncol 40 (1991) 55-65
5. Grigsby E.W., Perez C.S., Kuske R.R., et al. Results of therapy analysis of failures and prognostic factors for clinical and pathologic stage III adenocarcinoma of the endometrium. Gynecol Oncol 27 (1987) 44-57
6. Wolfson A. The Role of radiotherapy for high-risk endometrial cancer. Semin Radiat Oncol 10 (2000) 15-22
7. Genest P., Drouin P., Girard A., et al. Stage III carcinoma of the endometrium. A review of 41 cases. Gynecol Oncol 26 (1987) 77-86
8. Creasman W.T., Disaia P.J., Blessing J., et al. Prognostic significance of peritoneal cytology in patients with endometrial cancer and preliminary data concerning therapy with intraperitoneal radiopharmaceuticals. Am J Obstet Gynecol 141 (1981) 921-929
9. Potish R.A., Twiggs L.B., Adcock L.L., et al. Role of whole abdominal radiation therapy in the management of endometrial cancer. Prognostic importance of factors indicating peritoneal metastases. Gynecol Oncol 21 (1985) 80-86
10. Gibbons S., Martinez A., Schray M., et al. Adjuvant whole abdominopelvic irradiation for high-risk endometrial carcinoma. Int J Radiat Oncol Biol Phys 21 (1991) 1019-1025
11. Burke T.W., and Gershenson D.M. Chemotherpay as adjuvant and salvage treatment in women with endometrial carcinoma. Clin Obstet Gynecol 39 (1996) 716-727
12. Smith M.R., Peters W.A., Drescher C.W., et al. Cisplatin, doxorubicin hydrochloride and cyclophsophamide followed by radiotherapy in high-risk endometrial carcinoma. Am J Obstet Gynecol 170 (1994) 1677-1681
13. Morrow C.P., Bundy B.N., Homesley H.D., et al. doxorubicin as an adjuvant following surgery and radiation therapy in patients with high-risk endometrial carcinoma, stage I and occult stage II. A Gynecologic Oncology Group Study. Gynecol Oncol 36 (1999) 166-171
14. O'Brien M.E., and Killackey M. Adjuvant therapy in high risk endometrial adenocarcinoma. Proc Ann Meet Am Soc Clin Oncol 13 (1994) 249 (abstr)
15. Jennings S., Dotiino P., Johnston C., et al. Adjuvant cisplatin, doxorubicin, and etoposide and pelvic radiotherapy for advanced stage or virulent histologic subtypes of endometrial cancer. Proc Ann Meet Am Soc Clin Oncol 12 (1993) 268 (abstr)
16. Rosenberg P., Boeryd B., Simonsen E., et al. A new aggressive treatment approach to high-grade endometrial cancer of possible benefit to patients with stage I uterine papillary cancer. Gynecol Oncol 48 (1993) 32-37
17. Frigero L.L., Mangeli G.G., Aletti G.G., et al. Concomitant radiotherapy and paclitaxel for high-risk endometrial carcinoma. Feasibility study. Gynecol Oncol 76 (2000) 249 (abstr)
18. Greven K.M., Curran W.J., Whittington R., et al. Analysis of failure patterns in stage III endometrial carcinoma and therapeutic implications. Int J Radiot Oncol Biol Phys 17 (1989) 35-39
19. Corn B.W., Lanciano R.M., D'Agostino R., et al. The relationship of local and distant failure from endometrial cancer. Defining a clinical paradigm. Gyncol Oncol 66 (1997) 411-416
20. Greven K.M., Corn B., Lanciano R.M., et al. Pathologic stage III endometrial carcinoma. Significance of extrauterine sites. Radiat Oncol Invest 4 (1996) 122-128
21. Bruckman J.E., Bloomer W.D., Marck A., et al. Stage III adenocarcinoma of the endometrium. Two prognostic groups. Gynecol Oncol 9 (1980) 12-17
22. Connell P.P., Rotmensch J., Waggoner S., et al. The significance of adnexal involvement in endometrial carcinoma. Gynecol Oncol 74 (1999) 74-79
23. Ashman J.B., Connell P.P., Yamada D., et al. Outcome of endometrial carcinoma patients with involvement of the uterine serosa. Gynecol Oncol 82 (2001) 338-343
24. Mariani A., Webb M.J., Keeney G.L., et al. Stage III endometrioid corpus cancer includes distinct groups. Gynecol Oncol 87 (2002) 12-17
25. Nelson G., Randall M., Sutton G., et al. FIGO stage IIIC endometrial carcinoma with metastases confined to pelvic lymph nodes. Analysis of treatment outcomes, prognostic variables and failure patterns following adjuvant radiation therapy. Gynecol Oncol 75 (1999) 211-214
26. Hicks M.L., Piver S., Jeffrey L.P., et al. Survival in patients with paraaortic lymph node metastases from endometrial adenocarcinoma clinically limited to the uterus. Int J Radiat Oncol Biol Phys 26 (1993) 607-611
27. Rose P.G., Cha S.D., Tak W.K., et al. Radiation therapy for surgically proven para-aortic node metastasis in endometrial carcinoma. Int J Radiat Oncol Biol Phys 24 (1992) 229-233
28. Corn B.W., Lanciano R.M., Greven K.M., et al. Endometrial cancer with para-aortic adenopathy. Patterns of failure and opportunities for cure. Int J Radiat Oncol Biol Phys 24 (1992) 223-227
29. Martinez A., Schray M., Podratz K., et al. Postoperative whole abdomino-pelvic irradiation for patients with high risk endometrial cancer. Int J Radiait Oncol Biol Phys 17 (1989) 371-377
30. Sutton G., Axelrod J.H., Bundy B.N., et al. Whole abdominal radiotherapy in the adjuvant treatment of patients with stage III and IV endometrial cancer. A Gynecologic Oncology Group study. Gynecol Oncol 97 (2005) 755-763
31. Randall M.E., Filiaci V.L., Muss H., et al. A randomized phase III trial of whole abdominal irradiation versus doxorubicin-cisplatin chemotherapy in advanced endometrial carcinoma. A Gynecologic Oncology Group study. J Clin Oncol 24 (2006) 36-44
32. Martin J.D., Gilds B., Lim P., et al. Papillary serous carcinoma-A less radio-sensitive subtype of endometrial cancer. Gynecol Oncol 98 (2005) 299-303
33. Engleman M.A., and Small W. Combined modality therapy in the treatment of gynecologic malignancies. Semin Oncol 30 (2003) 80-94
34. Mundt A.J., McBride R., Rotmensch J., et al. Significant pelvic recurrence in high-risk pathologic stage I-IV endometrial carcinoma patients after adjuvant chemotherapy alone. Implications for adjuvant radiation therapy. Int J Radiat Oncol Biol Phys 50 (2001) 1145-1153
35. Faught W., Fung M., Krepart G.V., et al. Microscopic surgical stage IIIC endometrioid adenocarcinoma of the endometrium. Implications for bimodal adjuvant therapy. Int J Gynecol Cancer 8 (1998) 41-45
36. Aoki Y., Kase H., Watanabe M., et al. Stage III endometrial cancer. Analysis of prognostic factors and failure patterns after adjuvant chemotherapy. Gynecol Oncol 83 (2001) 1-5
37. Christman J.E., Kapp D.S., Hendrickson M.R., et al. Therapeutic approaches to uterine papillary serous carcinoma. A preliminary report. Gynecol Oncol 26 (1987) 228-235
38. Mallipeddi P., Kapp D.S., Teng N.H., et al. Long-term survival with adjuvant whole abdominopelvic irradiation for uterine papillary serous carcinoma. Cancer 71 (1993) 3076-3081
39. Grice J., EK M., Greer B., et al. Uterine papillary serous carcinoma. Evaluation of long-term survival in surgically stage patients. Gynecol Oncol 69 (1998) 69-73
40. Frank A.H., Tseng P.C., Haffty B.G., et al. Adjuvant whole-abdominal radiation therapy in uterine papillary serous carcinoma. Cancer 68 (1991) 1516-1519
41. Gehrig P.A., Skinner E.N., Boggess J.F., et al. Sequential chemotherapy and radiotherapy in women with stage III-IV uterine serous carcinoma (2005) (abstract 142). The Society of Gynecologic Oncologists' 36th Annual Meeting on Women's Cancer, Miami Beach, FL, March 19