Differential diagnosis and management of acute profound thrombocytopenia by tirofiban: A case report

Journal of Thrombosis and Thrombolysis

Volumn 22, Issue 1, 2006, Pages 77-78

  Demirkan, Burcu ^a   Guray, Yesim ^a   Guray, Umit ^a   Korkmaz, Sule ^a  

^a TURKIYE YUKSEK IHTISAS HOSPITAL   (Turkey)

Author keywords

GPIIb IIIa inhibitors; Thrombocytopenia; Tirofiban

Indexed keywords

ACETYLSALICYLIC ACID; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; GLYCERYL TRINITRATE; HEPARIN; TIROFIBAN;

ACUTE DISEASE; ADULT; BLEEDING; BLOOD SMEAR; CASE REPORT; CLINICAL FEATURE; DIFFERENTIAL DIAGNOSIS; DISSEMINATED INTRAVASCULAR CLOTTING; DRUG INFUSION; ENZYME LINKED IMMUNOSORBENT ASSAY; HEPARIN INDUCED THROMBOCYTOPENIA; HOSPITAL DISCHARGE; HUMAN; ISCHEMIC HEART DISEASE; MALE; PRIORITY JOURNAL; RETREATMENT; REVIEW; THROMBOCYTE COUNT; THROMBOCYTOPENIA; TREATMENT OUTCOME; TREATMENT WITHDRAWAL;

ACUTE DISEASE; DIAGNOSIS, DIFFERENTIAL; HUMANS; MALE; MIDDLE AGED; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; THROMBOCYTOPENIA; TYROSINE;

EID: 33745241389     PISSN: 09295305     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11239-006-7789-1     Document Type: Review

References (12)

1. Boersma E, Harrington EA, Moliterno DJ, et al. (2002) Platelet glycoprotein IIb/IIIa inhibi-tors in acute coronary syndromes: A meta-analysis of all majr randomized trials. Lancet 359:189-198
2. Karvouni E, Katritsis DG, Ioannidis J (2003) Intravenous glycoprotein IIb/IIIa receptor antagonists reduce mortality after percutaneous coronary interventions. J Am Coll Cardiol 41:26-32
3. RESTORE Investigators (1997) Effects of platelet glycoprotein IIb/IIIa blockade with tirofiban on adverse cardiac events in patients with unstable angina or acute myocardial infarction undergoing coronary angioplasty. Circulation 96:1445-1453
4. PRISM Study Investigators (1998) A comparision of aspirin plus tirofiban with aspirin plus heparin for unstable angina. N Engl J Med 338:1498-1505
5. PRISM-PLUS Study Investigators (1998) Inhibition of the platelet glycoprotein IIb/IIIa receptor with tirofiban in unstable angina and non Q-wave myocardial infarction. N Engl J Med 338:1488-1497
6. Bougie DW, Wilker PR, Wuitschick ED, et al. (2002) Acute thrombocytopenia after treatment with tirofiban or ebtifibatide is associated with antibodies spesific for ligand-occupied GPIIb/IIIa. Blood 100:2071-2076
7. BednarB, Cook JJ, Holahan MA, et al. (1999) Fibrinogen receptor antagonist-induced thrombocytopenia in chimpanzee and rhesus monkey associated with preexisting drug-dependent antibodies to platelet glycoprotein IIb/IIIa. Blood 94:587-599
8. Berkowitz SD, Harrington RA, Rund MM, et al. (1997) Acute profound thrombocytopenia after c7E3 Fab (Abciximab) therapy. Circulation 95:809-813
9. Holmes HB, Kabbani S, Watkins M, et al. (2000) Abciximab-associated pseudothrom-bocytopenia. Circulation 101:938-939
10. Warkentin TE, Aird WC, Rand JH (2003) Platelet-endothelial intereactions: sepsis, HIT and antiphospholipid syndrome. Hematology 497-519
11. Warkentin TE, Kelton JG (2001) Temporal aspects of heparin-induced thrompocytopenia. N Engl J Med 344:1286-1292
12. Llevadot J, Coulter SA, Giugliano RP (2000) A practical approach to diagnosis and management of thrombocytopenia associated with glycoprotein IIb/IIIa receptor inhibitors. J Thromb Thrombolysis 9:175-180