Does a "vanishing twin" affect first-trimester biochemistry in Down syndrome risk assessment?

American Journal of Obstetrics and Gynecology

Volumn 195, Issue 1, 2006, Pages 236-239

  Chasen, Stephen T ^a   Perni, Sriram C ^a   Predanic, Mladen ^a   Kalish, Robin B ^a   Chervenak, Frank A ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Down syndrome screening; Serum screening; Twin pregnancy; Vanishing twin

Indexed keywords

CHORIONIC GONADOTROPIN BETA SUBUNIT; PREGNANCY ASSOCIATED PLASMA PROTEIN A;

ADULT; ARTICLE; BIOCHEMISTRY; COMPARATIVE STUDY; CONTROLLED STUDY; DOWN SYNDROME; FEMALE; FETUS; FIRST TRIMESTER PREGNANCY; HUMAN; MATERNAL SERUM; MULTIPLE PREGNANCY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK ASSESSMENT; STATISTICAL ANALYSIS;

ABORTION, SPONTANEOUS; ADULT; CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN; DOWN SYNDROME; FEMALE; HUMANS; LOGISTIC MODELS; PREGNANCY; PREGNANCY TRIMESTER, FIRST; PREGNANCY, MULTIPLE; PREGNANCY-ASSOCIATED PLASMA PROTEIN-A; RISK ASSESSMENT;

EID: 33745240095     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2006.01.044     Document Type: Article

References (14)

1. Landy H.J., and Keith L.G. The vanishing twin: a review. Hum Reprod Update 4 (1998) 177-183
2. Dickey R.P., Taylor S.N., Lu P.Y., Sartor B.M., Storment J.M., Rye P.H., et al. Spontaneous reduction of multiple pregnancy: incidence and effect on outcome. Am J Obstet Gynecol 186 (2002) 77-83
3. Blumenfeld Z., Dirnfeld M., Abramovici H., Amit A., Bronshtein M., and Brandes J.M. Spontaneous fetal reduction in multiple gestations assessed by transvaginal ultrasound. BJOG 99 (1992) 333-337
4. Benirschke K. Intrauterine death of a twin: mechanisms, implications for surviving twin, and placental pathology. Semin Diagn Pathol 10 (1993) 222-231
5. Jauniaux E., Elkazen N., Leroy F., Wilkin P., Rodesch F., and Hustin J. Clinical and morphologic aspects of the vanishing twin phenomenon. Obstet Gynecol 72 (1988) 577-581
6. Kelly M.P., Molo M.W., Maclin V.M., Binor Z., Rawlins R.G., and Radwanska E. Human chorionic gonadotropin rise in normal and vanishing twin pregnancies. Fertil Steril 56 (1991) 221-224
7. Lynch L., and Berkowitz R.L. Maternal serum alpha-fetoprotein and coagulation profiles after multifetal pregnancy reduction. Am J Obstet Gynecol 169 (1993) 987-990
8. Nicolaides K.H. Nuchal translucency and other first-trimester sonographic markers of chromosomal abnormalities. Am J Obstet Gynecol 191 (2004) 45-67
9. Spencer K. Screening for trisomy 21 in twin pregnancies in the first trimester using free beta-hCG and PAPP-A, combined with fetal nuchal translucency thickness. Prenat Diagn 20 (2000) 91-95
10. Ventura S.J., Mosher W.D., Curtin S.C., Abma J.C., and Henshaw S. Trends in pregnancies and pregnancy rates by outcome: estimates for the United States, 1976-96. Vital Health Stat 21 56 (2000) 1-47
11. Russell R.B., Petrini J.R., Damus K., Mattison D.R., and Schwarz R.H. The changing epidemiology of multiple births in the United States. Obstet Gynecol 101 (2003) 129-135
12. O'Brien J.E., Dvorin E., Yaron Y., Ayoub M., Johnson M.P., Hume Jr. R.F., et al. Differential increases in AFP, hCG, and uE3 in twin pregnancies: impact on attempts to quantify Down syndrome screening calculations. Am J Med Genet 73 (1997) 109-112
13. Liao A.W., Heath V., Kametas N., Spencer K., and Nicolaides K.H. First-trimester screening for trisomy 12 in singleton pregnancies achieved by assisted reproduction. Hum Reprod 16 (2001) 1501-1504
14. Orlandi F., Rossi C., Allegra A., Krantz D., Hallahan T., Orlandi E., et al. First trimester screening with free beta-hCG, PAPP-A and nuchal translucency in pregnancies conceived with assisted reproduction. Prenat Diagn 22 (2002) 718-721