Unusually high incidence of hepatitis B virus integration into the MLL gene in hepatocellular carcinoma [1]

Clinical Cancer Research

Volumn 12, Issue 11 I, 2006, Pages 3549-

  Minami, Masahito ^a   Fujii, Kota ^a   Miyagawa, Masami ^a   Okanoue, Takeshi ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MIXED LINEAGE LEUKEMIA PROTEIN; PROTEIN MLL 2; PROTEIN MLL 4; RNA; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG;

DNA INTEGRATION; GENBANK; GENE AMPLIFICATION; GENE FREQUENCY; GENE SEQUENCE; HEPATITIS B VIRUS; HUMAN; LETTER; LIVER CELL CARCINOMA; MUTAGENESIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CARCINOMA, HEPATOCELLULAR; DNA, VIRAL; HEPATITIS B VIRUS; HUMANS; LIVER NEOPLASMS; MOLECULAR SEQUENCE DATA; MYELOID-LYMPHOID LEUKEMIA PROTEIN; POLYMERASE CHAIN REACTION; VIRUS INTEGRATION;

EID: 33745203452     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-06-0230     Document Type: Letter

References (4)

1. Tamori A, Yamanishi Y, Kawashima S, et al. Alteration of gene expression in human hepatocellular carcinoma with integrated hepatitis B virus DNA. Clin Cancer Res 2005;11:5821-6.
2. Ferber MJ, Montoya DP, Yu C, et al. Integrations of the hepatitis B virus (HBV) and human papillomavirus (HPV) into the human telomerase reverse transcriptase (hTERT) gene in liver and cervical cancers. Oncogene 2003;22:3813-20.
3. Murakami Y, Saigo K, Takashima H, et al. Large scaled analysis of hepatitis B virus (HBV) DNA integration in HBV related hepatocellular carcinomas. Gut 2005;54: 1162-8.
4. Wang Y, Lau SH, Sham JS, Wu MC, Wang T, Guan XY. Characterization of HBV integrants in 14 hepatocellular carcinomas: association of truncated X gene and hepatocellular carcinogenesis. Oncogene 2004;23:142-8.