Comparative effects of acute and subacute lycopene administration on chromosomal aberrations induced by cisplatin in male rats

Food and Chemical Toxicology

Volumn 44, Issue 8, 2006, Pages 1334-1339

  Sendão, Milena Cristina ^a   Behling, Estela Beatriz ^a   dos Santos, Raquel Alves ^b   Antunes, Lusânia Maria Greggi ^b,c   Bianchi, Maria de Lourdes Pires ^b  

^a Fac Ci Farmaceut   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c FEDERAL UNIVERSITY OF TRIÂNGULO MINEIRO   (Brazil)

Author keywords

Anticlastogenicity; Chromosome aberrations; Cisplatin; Clastogenicity; Lycopene

Indexed keywords

ANTINEOPLASTIC AGENT; CAROTENOID; CISPLATIN; CLASTOGEN; LYCOPENE; LYCORED; PLATINIL;

ACUTE DRUG ADMINISTRATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BONE MARROW CELL; CHROMOSOME ABERRATION; CHROMOSOME DAMAGE; CHRONIC DRUG ADMINISTRATION; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOGENETICS; CYTOTOXICITY; DOSE RESPONSE; DRUG EFFECT; MALE; METAPHASE; NONHUMAN; PHARMACOGENETICS; PROTECTION; RAT; RISK REDUCTION; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

ANIMALS; ANTIOXIDANTS; BONE MARROW CELLS; CAROTENOIDS; CHROMOSOME ABERRATIONS; CISPLATIN; DRUG INTERACTIONS; MALE; RATS; RATS, WISTAR; STATISTICS, NONPARAMETRIC;

ANIMALIA;

EID: 33745197966     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2006.02.010     Document Type: Article

References (40)

1. Antunes L.M.G., Darin J.D.C., and Bianchi M.L.P. Anticlastogenic effect of vitamin C on cisplatin in vivo. Genetics and Molecular Biology 22 (1999) 415-417
2. Antunes L.M.G., Araújo M.C.P., Darin J.D.C., and Bianchi M.L.P. Effects of the antioxidants curcumin and vitamin C on cisplatin-induced clastogenesis in Wistar rat bone marrow cells. Mutation Research 465 (2000) 131-137
3. Antunes L.M.G., Pascoal L.M., Bianchi M.L.P., and Dias F.L. Evaluation of the clastogenicity and anticlastogenicity of the carotenoid bixin in human lymphocyte cultures. Mutation Research 585 (2005) 113-119
4. Arab L., and Steck S. Lycopene and cardiovascular disease. American Journal of Clinical Nutrition 71 (2000) 1691S-1695S
5. Atessahin A., Yilmaz S., Karahan I., Ceribasi A.O., and Karaoglu A. Effects of lycopene against cisplatin-induced nephrotoxicity and oxidative stress in rats. Toxicology 212 (2005) 116-123
6. Burim R.V., Canalle R., Lopes J.L.C., Vichnewski W., and Takahashi C.S. Genotoxic action of the sesquiterpene lactone centratherin on mammalian cells in vitro and in vivo. Teratogenesis, Carcinogenesis and Mutagenesis 21 (2001) 383-393
7. Boileau W.M., Boileau A.C., and Erdman Jr. J.W. Bioavailability of all-trans and cis isomers of lycopene. Biology and Medicine 227 (2002) 914-919
8. Bramley P.M. Is lycopene beneficial to human health?. Phytochemistry 54 (2000) 233-236
9. Çelik A., Mazmanci B., Çamlica Y., Çömelekoglu U., and Aşkin A. Evaluation of cytogenetic effects of lambda-cyhalothrin on Wistar rat bone marrow by gavage administration. Ecotoxicology and Environmental Safety 61 (2005) 128-133
10. Conklin K.A. Cancer chemotherapy and antioxidants. Journal of Nutrition 134 (2004) 3201S-3204S
11. Di Mascio P., Kaiser S., and Sies H. Lycopene as the most efficient biological carotenoid singlet oxygen quencher. Archives of Biochemistry and Biophysical 274 (1989) 532-538
12. Edelweiss M.I., Trachtenberg A., Pinheiro E.X., Da-Silva J., Riegel M., Lizardo-Daudt H.M., and Mattevi M.S. Clastogenic effect of cisplatin on Wistar rat bone marrow cells. Brazilian Journal of Medicine and Biology Research 28 (1995) 679-683
13. Elsendoorn T.J., Weijl N.I., Mithoe S., Zwinderman A.H., Van Ddam F., De Zwart F.A., Tates A.D., and Osanto S. Chemotherapy-induced chromosomal damage in peripheral blood lymphocytes of cancer patients supplemented with antioxidants or placebo. Mutation Research 498 (2001) 145-158
14. Evangelista C.M.W., Antunes L.M.G., Francescato H.D.C., and Bianchi M.L.P. Effects of olive, extra virgin olive and canola oils on cisplatin-induced clastogenesis in Wistar rats. Food and Chemical Toxicology 42 (2004) 1291-1297
15. Giaccone G. Clinical perspectives on platinum resistance. Drugs 59 (2000) 9-17
16. Lowe G.M., Booth L.A., Young A.J., and Bilton R.F. Lycopene and β carotene protect against oxidative damage in HT29 cells at low concentrations but rapidly lose this capacity at higher doses. Free Radical Research 30 (1999) 141-151
17. Lynch E.D., Gu R., Pierce C., and Kil J. Combined oral delivery of ebselen and allopurinol reduces multiple cisplatin toxicities in rat breast and ovarian cancer models while enhancing anti-tumor activity. Anticancer Drugs 16 (2005) 569-579
18. Masuda H., Takaka T., and Takahama U. Cisplatin generates superoxide anion by interaction with DNA in a cell-free system. Biochemical and Biophysical Research Communications 203 (1994) 1175-1180
19. Mellert W., Deckardt K., Gembardt C., Schulte S., Ravenzwaay B., and Slesinski R.S. Thirteen-week oral toxicity study of synthetic lycopene products in rats. Food and Chemical Toxicology 40 (2002) 1581-1588
20. Mora L.O., Antunes L.M.G., Francescato H.D.C., and Bianchi M.L.P. The effects of oral glutamine on cisplatin-induced genotoxicity in Wistar rat bone marrow cells. Mutation Research 518 (2002) 65-70
21. Mukhopadhyay M., Mukherjee A., and Chakrabarti J. In vivo cytogenetic studies on blends of aspartame and acesulfame-K. Food and Chemical Toxicology 38 (2000) 75-77
22. Mure K., and Rossman T.G. Reduction of spontaneous mutagenesis in mismatch repair-deficient and proficient cells by dietary antioxidants. Mutation Research 480-481 (2001) 85-95
23. Narisawa T., Fukaura Y., Hasebe M., Ito M., Aizawa R., Murakoshi M., Uemura S., Khachik F., and Nishino H. Inhibitory effects of natural carotenoids, α-carotene, β-carotene, lycopene and lutein, on colonic aberrant crypt foci formation in rats. Cancer Letters 107 (1996) 137-142
24. Osanto S., Thijssen J.C., Woldering V.M., Van Rijn J.L., Natarajan A.T., and Tates A.D. Increased frequency of chromosomal damage in peripheral blood lymphocytes up to nine years following curative chemotherapy of patients with testicular carcinoma. Environmental and Molecular Mutagenesis 17 (1991) 71-78
25. Ouanes Z., Ayed-Boussema I., Baati T., Creppy E.E., and Bacha H. Zearalenone induces chromosome aberrations in mouse bone marrow: preventive effect of 17beta-estradiol, progesterona and vitamin E. Mutation Research 565 (2005) 139-149
26. Preston R.J., Dean B.J., Galloway S., Holden H., McFee A.F., and Shelby M. Mammalian in vivo cytogenetic assays: analysis of chromosome aberrations in bone marrow cells. Mutation Research 189 (1987) 157-165
27. Reifen R., Nur T., Matas Z., and Halpern Z. Lycopene supplementation attenuates the inflammatory status of colitis in a rat model. International Journal of Vitamins and Nutrition Research 71 (2001) 347-351
28. Romanchik J.E., Harrison E.H., and Morel D.W. Addition of lutein, lycopene, or β carotene to LDL or serum in vitro: effects on carotenoid distribution, LDL composition, and LDL oxidation. Nutritional Biochemistry 8 (1997) 681-688
29. Salvadori D.M.F., Ribeiro L.R., Oliveira M.D.M., Pereira C.A.B., and Beçak W. The protective effect of β-carotene on genotoxicity induced by cyclophosphamide. Mutation Research 265 (1992) 237-244
30. Shimeda Y., Hirotani Y., Akimoto Y., Shindou K., Ijiri Y., Nishihori T., and Takaka K. Protective effects of capsaicin against cisplatin-induced nephrotoxicity in rats. Biological and Pharmaceutical Bulletin 28 (2005) 1635-1638
31. Silva C.R., Antunes L.M.G., and Bianchi M.L.P. Antioxidant action of bixin against cisplatin-induced chromosome aberrations and lipid peroxidation in rats. Pharmacological Research 43 (2001) 561-566
32. Stahl W., and Sies H. Bioactivity and protective effects of natural carotenoids. Biochemica et Biophysica Acta 1740 (2005) 101-107
33. Swierenga S.H.H., Heddle J.A., Sigal E.A., Gilman J.P.W., Brillinger R.R.L., Douglas G.R., and Nestmann E.R. Recommended protocols based on a survey of current practice in genotoxicity testing laboratories, IV. Chromosome aberration and sister chromatid exchange in Chinese hamster ovary, V79 Chinese hamster lung and lymphocyte cultures. Mutation Research 246 (1991) 301-322
34. Tewari A., Chauhan L.K., Kumar D., and Gupta S.K. Municipal sludge leachate-induced genotoxicity in mice - a subacute study. Mutation Research 587 (2005) 9-15
35. Tice R.R., Luke C.A., and Shelby M.D. Methyl isocyanate: an evaluation of in vivo cytogenetic activity. Environmental Mutagenesis 9 (1987) 37-58
36. Velmurugan B., Bhuvaneswari V., Abraham S., and Nagini S. Protective effect of tomato against N-methyl-N-nitro-N-nitrosoguanidine-induced in vivo clastogenicity and oxidative stress. Basic Nutritional Investigation 20 (2004) 812-816
37. Weijl N.I., Cleton F.J., and Osanto S. Free radicals and antioxidants in chemotherapy-induced toxicity. Cancer and Treatment Reviews 23 (1997) 209-240
38. Weijl N.I., Elsendoorn T.J., Lentjes F.G., Hopman G.D., Wipkink-Bakker A., Zwinderman A.H., Cleton F.J., and Osanto S. Supplementation with antioxidant micronutrients and chemotherapy-induced toxicity in cancer patients treated cisplatin-based chemotherapy: a randomised, double-bind, placebo-controlled study. European Journal of Cancer 40 (2004) 1713-1723
39. Wozniak K., Czechowska A., and Blasiak J. Cisplatin-evoked DNA fragmentation in normal and cancer cells and its modulation by free radical scavengers and the tyrosine kinase inhibitor STI571. Chemical and Biological Interactions 147 (2004) 309-318
40. Young A.J., and Lowe G.M. Antioxidant and prooxidant properties of carotenoids. Archives of Biochemical and Biophysical 385 (2001) 20-27