Long-term quiescence of ectopic Cushing's syndrome caused by pulmonary neuroendocrine tumor (typical carcinoid) and tumorlets: Spontaneous remission or therapeutic effect of bromocriptine?

Journal of Endocrinological Investigation

Volumn 29, Issue 4, 2006, Pages 358-362

  Francia, G ^a,b   Davi M V ^a   Montresor, E ^a   Colato, C ^a   Ferdeghini, M ^a   Lo Cascio, V ^a  

^a UNIVERSITY OF VERONA   (Italy)

^b Policlinico GB Rossi   (Italy)

Author keywords

Bromocriptine; Ectopic Cusing's syndrome

Indexed keywords

BROMOCRIPTINE; CORTICOTROPIN; CYPROHEPTADINE; HYDROCORTISONE; SPIRONOLACTONE;

ADRENAL FUNCTION; ADULT; ARTICLE; CASE REPORT; CLINICAL PROTOCOL; COMPUTER ASSISTED TOMOGRAPHY; CORTICOTROPIN RELEASE; CUSHING DISEASE; CUSHING SYNDROME; DIABETES MELLITUS; DISEASE SEVERITY; DRUG DOSE REGIMEN; DRUG WITHDRAWAL; FEMALE; FOLLOW UP; HOSPITAL ADMISSION; HUMAN; HUMAN TISSUE; HYPERCORTISOLISM; HYPOKALEMIA; IMMUNOHISTOCHEMISTRY; LOBECTOMY; LUNG PARENCHYMA; LUNG TUMOR; NEUROENDOCRINE TUMOR; NEUROSECRETORY CELL; RELAPSE; THORAX RADIOGRAPHY; TUMOR REGRESSION;

EID: 33745190731     PISSN: 03914097     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03344109     Document Type: Article

References (23)

1. Carpenter PC. Diagnostic and evaluation of Cushing's syndrome. Endocrinol Metab Clin North Am 1988, 17: 445-72.
2. Thorner MO, Martin WH, Ragan GE, et al. A case of ectopic ACTH syndrome: diagnostic difficulties caused by intermittent hormone secretion. Acta Endocrinol (Copenh) 1982, 99: 364-70.
3. Findling JW, Tyrrel JB. Occult ectopic secretion of corticotropin. Arch Intern Med 1986, 146: 929-33.
4. Wajchenberg BL, Mendonca BB, Liberman BM, et al. Ectopic adrenocorticotropic hormone syndrome. Endocr Rev 1994, 15: 752-87.
5. Lamberts SW, de Lange SA, Stefanko SZ. Adrenocorticotropin-secreting pituitary adenoms originate from the anterior or intermediate lobe in Cuhing's disease: differences in the regulation of hormone secretion. J Clin Endocrinol Metab 1982, 54: 286-91.
6. Mc Nicol AM, Teasdale GM, Beastall GH. A study of corticotroph adenomas in Cushing's disease: no evidence of intermediate lobe origin. Clin Endocrinol (oxf) 1986, 24: 715-22.
7. Raffel C, Boggan JE, Eng LF, Davis RL, Wilson CB. Pituitary adenomas in Cushing's disease: do they arise from the intermediate lobe? Surg Neurol 1988, 30: 125-30.
8. Reith P, Monnot EA, Bathija PJ. Prolonged suppression of a corticotropin-producing bronchial carcinoid by oral bromocriptine. Arch Intern Med 1987, 147: 989-91.
9. Lemmer K, Ahnert-Hilger G, Hopfner M, et al. Expression of dopamine receptors and transporter in neuroendocrine gastrointestinal tumor cells. Life Sci 2002, 71: 667-78.
10. Ishibashi M, Fujisawa M, Furue H, Maeda Y, Fukayama M, Yamaji T. Inhibition of growth of human cell lung cancer by bromocriptine. Cancer Res 1994, 4: 3442-6.
11. Farrel WE, Clark AJ, Stewart MF, Crosby SR, White A. Bromocriptine inhibits pro-opiomelonocortin mRNA and ACTH precursor secretion in small cell lung cancer cell lines. J Clin Invest 1992, 90: 705-10.
12. Bailey RE. Periodic hormonogenesis. Periodicity of a hormone producing tumor in man. J Clin Endocrinol Metab 1971, 32: 317-27.
13. Shapiro MS, Gutman A, Bruderman I, Myers B, Griffel WB. Cushing's syndrome associated with a bronchial adenoma. Possible periodic hormonogenesis. Isr J Med Sci 1975, 11: 919-24.
14. Chajek T, Romanoff H. Cushing syndrome with cyclical edema and periodic secretion of corticosteroid. Arch Intern Med 1976, 136: 441-3.
15. Arnaldi G, Mancini T, Kola B, et al. Cyclical Cushing's syndrome in a patient with a bronchial neuroendocrine tumor (typical carcinoid) expressing ghrelin and growth hormone secretagogue receptors. J Clin Endocrinol Metab 2003, 88: 5834-40.
16. Watanobe H, Aoki R, Takebe K, Nakazono M, Kudo M. In vivo and in vitro studies in a patient with cyclic Cushing's disease showing some responsiveness to bromocriptine. Horm Res 1991, 36: 227-34.
17. Rodgers-Sullivan RF, Weiland LH, Palumbo PJ, Hepper MG. Pulmonary tumorlets associated with Cushing's syndrome. Am Rev Respir Dis 1978, 117: 799-806.
18. Ranchod M. The histogenesis and development of pulmonary tumorlets Cancer 1977, 39: 1135-45.
19. Arioglu E, Doppman J, Gomes M, et al. Cushing's syndrome caused by corticotropin secretion by pulmonary tumorlets. N Eng J Med 1998, 339: 883-6.
20. Ozbey N, Bozbora A, Kalayci G, et al. Cushing's syndrome caused by ectopic corticotropin secretion by multiple peripheral pulmonary carcinoids and tumorlets of carcinoid type. J Endocrinol Invest 2000, 23: 536-41.
21. Povedano ST, Pastor CV, Seoane CP, et al. Ectopic ACTH syndrome caused by pulmonary carcinoid tumourlets. Clin Endocrinol (Oxf) 2001, 54: 839-42.
22. Liu SM, Wu HH, Wu CJ, Kuo CL, Mo LR. Adrenocorticotropin producing pulmonry tumorlets with lymph node metastasis. Pathol Int 2003, 53: 883-6.
23. Yasuda K, Miura K. Unique type of Cushing's disease in clinical profile: cyclic Cushing's syndrome and Cushing's disease with favorable outcome to high daily dose of bromocriptine. Nippon Naibunpi Gakkai Zasshi 1994, 20:70.