Cytogenetic and immunological changes after dermal exposure to polycyclic aromatic hydrocarbons and UV radiation

Physiological Research

Volumn 55, Issue 3, 2006, Pages 317-323

  Borska L ^a   Fiala, Z ^a   Krejsek, J ^b   Hamakova K ^b   Andrys C ^b   Smejkalova J ^a   Vokurkova D ^b   Kremlacek J ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

^b UNIVERSITY HOSPITAL HRADEC KRALOVE   (Czech Republic)

Author keywords

Genotoxicity; Immunotoxicity; Polycyclic aromatic hydrocarbons; Psoriasis; UV radiation

Indexed keywords

ALPHA 2 MACROGLOBULIN; BETA 2 MICROGLOBULIN; BIOLOGICAL MARKER; COAL TAR; IMMUNOGLOBULIN E; IMMUNOGLOBULIN M; POLYCYCLIC AROMATIC HYDROCARBON; TRANSFERRIN;

ADULT; ARTICLE; BLOOD SAMPLING; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOGENETICS; DISEASE MARKER; DISEASE SEVERITY; EXPOSURE; FEMALE; GENOTOXICITY; HUMAN; HUMAN CELL; IMMUNITY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOLOGICAL PARAMETERS; IMMUNOMODULATION; IMMUNOTOXICITY; MALE; MEDICAL PARAMETERS; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; PERIPHERAL LYMPHOCYTE; PHOTOTHERAPY; PROTEIN BLOOD LEVEL; PSORIASIS; RADIATION EXPOSURE; RADIATION MUTAGENESIS; RISK FACTOR; SCORING SYSTEM; SKIN; TREATMENT DURATION; ULTRAVIOLET RADIATION;

ADMINISTRATION, CUTANEOUS; ADULT; ALPHA-MACROGLOBULINS; BETA 2-MICROGLOBULIN; CHROMOSOME ABERRATIONS; COAL TAR; FEMALE; HUMANS; IMMUNE SYSTEM; IMMUNOGLOBULIN E; IMMUNOGLOBULIN M; LYMPHOCYTES; MALE; POLYCYCLIC HYDROCARBONS, AROMATIC; PSORIASIS; SEVERITY OF ILLNESS INDEX; SKIN; TRANSFERRIN; TREATMENT OUTCOME; ULTRAVIOLET THERAPY;

EID: 33745189622     PISSN: 08628408     EISSN: 08628408     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. AHEM: Methods of biological monitoring of genotoxic effects of environmental factors. Cytogenetic analyses of peripheral lymphocytes. Actualization of valid standard method. (in Czech). Acta Hyg Epidem Microbiol 5 (Suppl): S22, 2000.
2. BENÁKOVÁ N: Pharmacotherapy of psoriasis. (in Czech.) Remedia 11: 25-34, 2001.
3. BORSKÁ L, FIALA Z, HAMÁKOVÁ K, ANDRÝS C, KREJSEK J, VOKURKOVÁ D, ŠMEJKALOVÁ J, KREMLÁČ EK J: Selected cytogenetic and immunological changes after dermal exposure to polycyclic aromatic hydrocarbons (PAHs). Physiol Res 53: 48P, 2004a.
4. BORSKÁ L, FIALA Z, ŠMEJKALOVÁ J, HAMÁKOVÁ K, KREMLÁČEK J: Possible genotoxic risk of combined exposure to pharmaceutical coal tar and UV-B radiation. Cent Eur J Public Health 12 (Suppl): S14-S15, 2004b.
5. CHODOROWSKA G, JUSZKIEWICZ-BOROWIEC M, CZELEJ D, WOJNOWSKA D, KOWAL M: Activity of tumor necrosis factor-alfa (TNF-alpha) and selected acute phase proteins in plasma of psoriatic patients receiving local treatment. Ann Univ Mariae Curie Sklodowska 56: 165-169, 2001.
6. 2-macroglobulin plasma activity medium-severe and severe psoriasis. J Eur Acad Dermatol Venereol 18: 180-183, 2004.
7. CLONFERO E, JONGENEELEN F, ZORDAN M, LEVIS AG: Biological monitoring of human exposure to coal tar. Urinary mutagenicity assays and analytical determination of polycyclic aromatic hydrocarbon metabolites in urine. IARC Sci Publ 104: 215-222, 1990.
8. ESPINOZA LR, CUELLAR ML, SILVEIRA LH: Psoriatic arthritis. Curr Opin Rheumatol 4: 470-478, 1992.
9. ETTLER K: Clinical evaluation of psoriasis and atopic eczema expressed as indexes. (in Czech) Čs Dermatol 70: 45-47, 1995.
10. FIALA Z, BORSKÁ L, VYSKOČIL A, MAŠÍN V, SRB V: Polycyclic aromatic hydrocarbons II. Toxic effects. (in Czech) Acta Med (Hradec Králové) 43 (Suppl): S37-S61, 2000.
11. FIALA Z, BORSKÁ L, HAMÁKOVÁ K, KRAJÁK V: Excretion of selected urinary metabolites after dermal exposure to polycyclic aromatic hydrocarbons (PAHs). Physiol Res 53: 50P, 2004.
12. GARDOŠOVÁ D, MEZENCEVOVÁ V, KALINA I, HEJJ F, KOPKA M, PETROVIČOVÁ J: Mutagenic effects of pharmaceutical coal tar in psoriatic patients (in Slovak). Bratisl Lek Listy 98: 146-149, 1997.
13. GUDJONSSON JE, JOHNSTON A, SIGMUNDSDOTTIR H, VALDIMARSSON H: Immunopathogenic mechanisms in psoriasis. Clin Exp Immunol 135: 1-8, 2004.
14. KRČMOVÁ I, HANZÁLKOVÁ Y: Is the immunomodulating effect of allergen immunotherapy allergen specific? Allergy 56: 89, 2001.
15. KREJSEK J, KOPECKÝ O: Clinic Immunology (in Czech). Nucleus, Hradec Králové, 2004, 985 p.
16. KUNDAKCI N, OSKAY T, ÖLMEZ Ü, TUTKAK H, GURGEY E: Association of psoriasis vulgaris with HLA class I and class II antigens in the Turkish population, according to the age at onset Int J Dermatol 41: 345-348, 2002.
17. LEBWOHL M, ALI S: Treatment of psoriasis. Part 1. Topical therapy and phototherapy. J Am Acad Dermatol 45: 487-498, 2001.
18. LUSTER MI, ROSENTHAL GJ: Chemical agents and the immune response. Environ Health Perspect 101: 219-226, 1993.
19. LÜLLMANN H, MOHR K, WEHLING M: Pharmacology and Toxicology. (in Czech) Grada, Prague, 2002, 696 p.
20. MEHLIS SL, GORDON KB: The immunology of psoriasis and biologic immunotherapy. J Am Acad Dermatol 49: 44-50, 2003.
21. NOVOTNÝ F: Psoriasis. Actual views (in Czech). Grada, Prague, 2002, 144 p.
22. OREM A, DEGER O, CIMSIT G, BAHADIR S: Plasma polymorphonuclear leukocyte elastase levels and its relation to disease activity in psoriasis. Clin Chim Acta 264: 49-56, 1997.
23. PRODANOVICH S, KIRSNER RS, TAYLOR JR: Treatment of patients hospitalized for psoriasis. Dermatol Clin 18: 425-435, 2000.
24. ROCHA-PEREIRA P, SANTOS-SILVA A, REBELO I, FIGUEIREDO A, QUINTANILHA A, TEIXEIRA F: The inflammatory response in mild and in severe psoriasis. Br J Dermatol 150: 917-928, 2004.
25. TELFER NR, CHALMERS RJ, WHALE K, COLMAN G: The role of streptococcal infection in the initiation of guttate psoriasis. Arch Dermatol 128: 39-42, 1994.
26. THAMI GP, SARKAR R: Coal tar: past, present and future. Clin Exp Dermatol 27: 99-103, 2002.
27. TRIPATHI A, CONLEY DB, GRAMMER LC, DITTO AM, LOWERY MM, SEIBERLING KA, YARNOLD PA, ZEIFER B, KERN RC: Immunoglobulin E to staphylococcal and streptococcal toxins patients with chronic sinusitis/nasal polyposis. Laryngoscope 114: 1822-1826, 2004.
28. VALDIMARSSON H, BAKER BS, JONSDOTTIR I, POWLES A, FRY L: Psoriasis: a disease of abnormal proliferation induced by T lymphocytes. Immunol Today 7: 256-259, 1986.
29. VALDIMARSSON H, BAKER, BS, JONSDOTTIR I, POWLES A, FRY L: Psoriasis: a T cell-mediated autoimmune disease induced by streptococcal superantigens? Immunol Today 16: 1445-1449, 1995.
30. WARIN AP: Dermatology day care treatment centres. Clin Exp Dermatol 26: 351-355, 2001.