Exertional rhabdomyolysis during a 246-km continuous running race

Medicine and Science in Sports and Exercise

Volumn 38, Issue 6, 2006, Pages 1054-1057

  Skenderi, Katerina P ^a   Kavouras, Stavros A ^a   Anastasiou, Costas A ^a   Yiannakouris, Nikos ^a   Matalas, Antonia Leda ^a  

^a HAROKOPIO UNIVERSITY   (Greece)

Author keywords

Creatine kinase; Lactate dehydrogenase; Spartathlon; Ultraendurance exercise

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CREATINE KINASE; GAMMA GLUTAMYLTRANSFERASE; LACTATE DEHYDROGENASE;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD SAMPLING; CREATINE KINASE BLOOD LEVEL; ENDURANCE; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; EXERCISE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; GREECE; HOSPITALIZATION; HUMAN; HUMAN EXPERIMENT; LACTATE DEHYDROGENASE BLOOD LEVEL; LIVER INJURY; MUSCLE INJURY; RHABDOMYOLYSIS; RUNNING;

ADULT; ALANINE TRANSAMINASE; ASPARTATE AMINOTRANSFERASES; BODY HEIGHT; BODY MASS INDEX; BODY WEIGHT; CREATINE KINASE; ERYTHROCYTE COUNT; ERYTHROCYTE INDICES; GAMMA-GLUTAMYLTRANSFERASE; HEMATOCRIT; HEMOGLOBINS; HUMANS; L-LACTATE DEHYDROGENASE; LEUKOCYTE COUNT; LIVER; MUSCLE, SKELETAL; PHYSICAL ENDURANCE; RHABDOMYOLYSIS; RUNNING; TIME FACTORS;

EID: 33745167295     PISSN: 01959131     EISSN: None     Source Type: Journal    
DOI: 10.1249/01.mss.0000222831.35897.5f     Document Type: Article

References (27)

1. AINSWORTH, B. E., W. L. HASKELL, M. C. WHITT, et al. Compendium of physical activities: an update of activity codes and MET intensities. Med. Sci. Sports Exerc. 32:S498-S504, 2000.
2. ARMSTRONG, R. B. Muscle damage and endurance events. Sports Med. 3:370-381, 1986.
3. BLAKE, J. Observations upon long-distance runners. Boston Mewd J. 148:195-206, 1903.
4. CHEVION, S., D. S. MORAN, Y. HELED, et al. Plasma antioxidant status and cell injury after severe physical exercise. Proc. Natl. Acad. Sci. U. S. A. 100:5119-5123, 2003.
5. DAVIDSON, R. J., J. D. ROBERTSON, G. GALEA, and R. J. MAUGHAN. Hematological changes associated with marathon running. Int. J. Sports Med. 8:19-25, 1987.
6. HIKIDA, R. S., R. S. STARON, F. C. HAGERMAN, W. M. SHERMAN, and D. L. COSTILL. Muscle fiber necrosis associated with human marathon runners. J. Neurol. Sci. 59:185-203, 1983.
7. HUNTER, J. B., and J. B. CRITZ. Effect of training on plasma enzyme levels in man. J. Appl. Physiol. 31:20-23, 1971.
8. KOLKA, M. A., L. A. STEPHENSON, and J. E. WILKERSON. Erythrocyte indices during a competitive marathon. J. Appl. Physiol. 52:168-172, 1982.
9. KRAEMER, R. R., and B. S. BROWN. Alterations in plasma-volume-corrected blood components of marathon runners and concomitant relationship to performance. Eur. J. Appl. Physiol. Occup. Physiol. 55:579-584, 1986.
10. KRATZ, A., K. B. LEWANDROWSKI, A. J. SIEGEL, et al. Effect of marathon running on hematologic and biochemical laboratory parameters, including cardiac markers. Am. J. Clin. Pathol. 118:856-863, 2002.
11. MARON, M. B., S. M. HORVATH, and J. E. WILKERSON. Acute blood biochemical alterations in response to marathon running. Eur. J. Appl. Physiol. Occup. Physiol. 34:173-181, 1975.
12. MARSHALL, W. Clinical Chemistry, 5th ed. London: Mosby, C.V., 2004, pp. 238-243.
13. NEWHAM, D. J., D. A. JONES, and R. H. EDWARDS. Large delayed plasma creatine kinase changes after stepping exercise. Muscle Nerve 6:380-385, 1983.
14. NOAKES, T. D. Effect of exercise on serum enzyme activities in humans. Sports Med. 4:245-267, 1987.
15. PALAZZETTI, S., M. J. RICHARD, A. FAVIER, and I. MARGARITIS. Overloaded training increases exercise-induced oxidative stress and damage. Can. J. Appl. Physiol. 28:588-604, 2003.
16. ROSE, L. I., J. E. BOUSSER, and K. H. COOPER. Serum enzymes after marathon running. J. Appl. Physiol. 29:355-357, 1970.
17. SAVERS, S. P., and P. M. CLARKSON. Short-term immobilization after eccentric exercise. Part II: creatine kinase and myoglobin. Med. Sci. Sports Exerc. 35:762-768, 2003.
18. SHASKEY, D. J., and G. A. GREEN. Sports haematology, Sports Med. 29:27-38, 2000.
19. SIEGEL, A. J., E. L. LEWANDROWSKI, K. Y. CHUN, M. B. SHOLAR, A. J. FISCHMAN, and K. B. LEWANDROWSKI. Changes in cardiac markers including B-natriuretic peptide in runners after the Boston marathon. Am. J. Cardiol. 88:920-923, 2001.
20. SIEGEL, A. J., M. SHOLAR, J. YANG, E. DHANAK, and K. B. LEWANDROWSKI. Elevated serum cardiac markers in asymptomatic marathon runners after competition: is the myocardium stunned? Cardiology 88:487-491, 1997.
21. SIEGEL, A. J., J. J. STEC, I. LIPINSKA, et al. Effect of marathon running on inflammatory and hemostatic markers. Am. J. Cardiol. 88:918-920, 2001. A919.
22. SORICHTER, S., J. MAIR, A. KOLLER, et al. Release of muscle proteins after downhill running in male and female subjects. Scand. J. Med. Sci. Sports. 11:28-32, 2001.
23. SPIROPOULOS, K., and G. TRAKADA. Hematologic and biochemical laboratory parameters before and after a marathon race. Lung 181:89-95, 2003.
24. STANSBIE, D., J. P. ASTON, N. S. DALLIMORE, H. M. WILLIAMS, and N. WILLIS. Effect of exercise on plasma pyruvate kinase and creatine kinase activity. Clin. Chim. Acta 132:127-132, 1983.
25. VAN RENSBURG, J. P., A. J. KIELBLOCK, and A. VAN DER LINDE. Physiologic and biochemical changes during a triathlon competition. Int. J. Sports Med. 7:30-35, 1986.
26. WARHOL, M. J., A. J. SIEGEL, W. J. EVANS, and L. M. SILVERMAN. Skeletal muscle injury and repair in marathon runners after competition. Am. J. Pathol. 118:331-339, 1985.
27. WHITING, P. H., R. J. MAUGHAN, and J. D. MILLER. Dehydration and serum biochemical changes in marathon runners. Eur. J. Appl. Physiol. Occup. Physiol. 52:183-187, 1984.