NH4+ modulates renal tubule amantadine transport independently of intracellular pH changes

European Journal of Pharmacology

Volumn 541, Issue 1-2, 2006, Pages 87-94

  Goralski, Kerry B ^a,b   Bose, Ratna ^a   Sitar, Daniel S ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Amantadine; Ammonium ion; Bicarbonate; Kidney; Organic cation transport

Indexed keywords

AMANTADINE; BICARBONATE; ORGANIC CATION TRANSPORTER; PROPIONIC ACID DERIVATIVE; TETRYLAMMONIUM; TETRYLAMMONIUM CHLORIDE; AMMONIUM CHLORIDE; AMMONIUM NITRATE; AMMONIUM PHOSPHATE; AMMONIUM SULFATE; NITRATE; PHOSPHATE; PROPIONATE SODIUM; QUATERNARY AMMONIUM DERIVATIVE;

ACIDIFICATION; ALKALINIZATION; ANIMAL TISSUE; ARTICLE; CELL PH; CONTROLLED STUDY; DOSE RESPONSE; DRUG TRANSPORT; DRUG UPTAKE; FEMALE; KIDNEY PROXIMAL TUBULE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; DRUG EFFECT; IN VITRO STUDY; KIDNEY TUBULE; KINETICS; METABOLISM; PH; TIME; TRANSPORT AT THE CELLULAR LEVEL;

AMANTADINE; AMMONIUM CHLORIDE; AMMONIUM SULFATE; ANIMALS; BICARBONATES; BIOLOGICAL TRANSPORT; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDROGEN-ION CONCENTRATION; KIDNEY TUBULES; KIDNEY TUBULES, PROXIMAL; KINETICS; NITRATES; PHOSPHATES; PROPIONIC ACIDS; QUATERNARY AMMONIUM COMPOUNDS; RATS; TETRAETHYLAMMONIUM; TIME FACTORS;

EID: 33745120175     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.04.051     Document Type: Article

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