Relationship between self-reported odor intolerance and sensitivity to inhaled capsaicin: Proposed definition of airway sensory hyperreactivity and estimation of its prevalence

Chest

Volumn 129, Issue 6, 2006, Pages 1623-1628

  Johansson, Åke ^a   Millqvist, Eva ^b   Nordin, Steven ^c   Bende, Mats ^a  

^a CENTRAL HOSPITAL   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^c UMEÅ UNIVERSITY   (Sweden)

Author keywords

Capsaicin; Chemical sensitivity; Epidemiology; Odor intolerance; Sensory hyperreactivity

Indexed keywords

CAPSAICIN;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BRONCHUS HYPERREACTIVITY; BRONCHUS OBSTRUCTION; COUGHING; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; INHALATION; MAJOR CLINICAL STUDY; MALE; MULTIPLE CHEMICAL SENSITIVITY; NERVE FIBER C; ODOR INTOLERANCE; OLFACTORY DISCRIMINATION; POPULATION RESEARCH; PREVALENCE; PRIORITY JOURNAL; PROVOCATION TEST; QUESTIONNAIRE; SELF REPORT; SEX RATIO; STATISTICAL ANALYSIS; SWEDEN; UNSPECIFIED SIDE EFFECT;

EID: 33745117998     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.129.6.1623     Document Type: Article

References (39)

1. Bell IR, Schwartz GE, Peterson JM, et al. Self-reported illness from chemical odors in young adults without clinical syndromes or occupational exposures. Arch Environ Health 1993; 48:6-13
2. Johansson A, Bramerson A, Millqvist E, et al. Prevalence and risk factors for self-reported odour intolerance: the Skovde population-based study. Int Arch Occup Environ Health 2005; 78:559-564
3. Kreutzer R, Neutra RR, Lashuay N. Prevalence of people reporting sensitivities to chemicals in a population-based survey. Am J Epidemiol 1999; 150:1-12
4. Meggs WJ, Dunn KA, Bloch RM, et al. Prevalence and nature of allergy and chemical sensitivity in a general population. Arch Environ Health 1996; 51:275-282
5. Millqvist E, Johansson A, Bende M. Relationship of airway symptoms from chemicals to capsaicin cough sensitivity in atopic subjects. Clin Exp Allergy 2004; 34:619-623
6. Millqvist E, Bende M, Löwhagen O. Sensory hyperreactivity: a possible mechanism underlying cough and asthma-like symptoms. Allergy 1998; 53:1208-1212
7. Ternesten-Hasseus E, Farbrot A, Löwhagen O, et al. Sensitivity to methacholine and capsaicin in patients with unclear respiratory symptoms. Allergy 2002; 57:501-507
8. Millqvist E. Cough provocation with capsaicin is an objective way to test sensory hyperreactivity in patients with asthma-like symptoms. Allergy 2000; 55:546-550
9. Johansson A, Löwhagen O, Millqvist E, et al, Capsaicin inhalation test for identification of sensory hyperreactivity. Respir Med 2002; 96:731-735
10. Millqvist E, Löwhagen O, Bende M. Quality of life and capsaicin sensitivity in patients with sensory airway hyperreactivity. Allergy 2000; 55:540-545
11. Ternesten-Hasseus E, Johansson A, Lowhagen O, et al. Inhalation method determines outcome of capsaicin inhalation in patients with chronic cough due to sensory hyperreactivity. Pulm Pharmacol Ther 2006; 19:172-178
12. Karlsson J-A, Sant'Ambrogio G, Widdicombe J. Afferent neural pathways in cough and reflex bronchoconstriction. J Appl Physiol 1988; 65:1007-1023
13. Midgren B, Hansson L, Karlsson J-A, et al. Capsaicin-induced cough in humans. Am Rev Respir Dis 1992; 146:347-351
14. Dicpinigaitis PV. Short- and long-term reproducibility of capsaicin cough challenge testing. Pulm Pharmacol Ther 2003; 16:61-65
15. Doherty MJ, Mister R, Pearson MG, et al. Capsaicin responsiveness and cough in asthma and chronic obstructive pulmonary disease. Thorax 2000; 55:643-649
16. Fujimura M, Kamio Y, Hashimoto T, et al. Effect of capsaicin inhalation on methacholine responsiveness in normal subjects. Clin Auton Res 1996; 6:45-48
17. Hansson L, Choudry NB, Karlsson JA, et al. Inhaled nicotine in humans: effect on the respiratory and cardiovascular systems. J Appl Physiol 1994; 76:2420-2427
18. Caterina MJ, Julius D. The vanilloid receptor: a molecular gateway to the pain pathway. Annu Rev Neurosci 2001; 24:487-517
19. James DE, Nijkamp FP. Neuro-immune interactions in the lung. Clin Exp Allergy 1997; 29:1309-1319
20. Hansson L, Midgren B, Karlsson JA. Effects of inhaled lignocaine and adrenaline on capsaicin-induced cough in humans. Thorax 1994; 49:1166-1168
21. Nordin S, Millqvist E, Lowhagen O, et al. A short chemical sensitivity scale for assessment of airway sensory hyperreactivity. Int Arch Occup Environ Health 2004; 77:249-254
22. Nordin S, Bende M, Millqvist E. Normative data of the chemical sensitivity scale. J Environ Psychol 2004; 77:399-403
23. Nordin S, Millqvist E, Löwhagen O, et al. The chemical sensitivity scale: Psychometric properties and comparison with the noise sensitivity scale. J Environ Psychol 2003; 23:359-367
24. Altman DG, Machin D, Bryant TN, et al. Statistics with confidence. 2nd ed. Bristol, UK: JW, Arrowsmith Ltd, 2000
25. Hansson L, The human cough reflex in health and disease. PhD dissertation, University of Lund, Lund, Sweden 1995
26. Haque RA, Usmani OS, Barnes PJ. Chronic idiopathic cough: a discrete clinical entity? Chest 2005; 127:1710-1713
27. Choudry NB, Fuller RW. Sensitivity of the cough reflex in patients with chronic cough. Eur Respir J 1992; 5:296-300
28. O'Connell F, Thomas VE, Pride NB, et al. Capsaicin cough sensitivity decreases with successful treatment of chronic cough. Am J Respir Crit Care Med 1994; 150:374-380
29. Kastelik JA, Thompson RH, Aziz I, et al. Sex-related differences in cough reflex sensitivity in patients with chronic cough. Am J Respir Crit Care Med 2002; 166:961-964
30. Nieto L, de Diego A, Perpina M, et al. Cough reflex testing with inhaled capsaicin in the study of chronic cough. Respir Med 2003; 97:393-400
31. Morice AH, Kastelik JA. Cough: 1. Chronic cough in adults. Thorax 2003; 58:901-907
32. Morice AH, Fontana GA, Sovijarvi AR, et al. The diagnosis and management of chronic cough. Eur Respir J 2004; 24:481-492
33. Chung KF, Widdicombe J. Acute and chronic cough. Pulm Pharmacol Ther 2004; 17:471-473
34. Cho YS, Park SY, Lee CK, et al. Elevated substance P levels in nasal lavage fluids from patients with chronic nonproductive cough and increased cough sensitivity to inhaled capsaicin. J Allergy Clin Immunol 2003; 112:695-701
35. Dicpinigaitis PV, Alva RV. Safety of capsaicin cough challenge testing. Chest 2005; 128:196-202
36. Dicpinigaitis PV. Cough reflex sensitivity in cigarette smokers. Chest 2003; 123:685-688
37. Millqvist E, Bende M. Capsaicin cough sensitivity is decreased in smokers. Respir Med 2001; 95:19-21
38. Weinfeld D, Ternesten-Hasseus E, Lowhagen O, et al. Capsaicin cough sensitivity in allergic asthmatic patients increases during the birch pollen season. Ann Allergy Asthma Immunol 2002; 89:419-424
39. Aronowitz RA. When do symptoms become a disease? Ann Intern Med 2001; 134:803-808