Gastric acid-suppressive agents and risk of Clostridium difficile-associated disease [2]

JAMA

Volumn 295, Issue 22, 2006, Pages 2599-2600

  Leffler, Daniel ^a   Cloud, Jeffery W ^a   Kelly, Ciaran P ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

STOMACH SECRETION INHIBITOR; ANTIINFECTIVE AGENT; GASTROINTESTINAL AGENT; HISTAMINE H2 RECEPTOR ANTAGONIST; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE;

BACTERIAL INFECTION; CLOSTRIDIUM DIFFICILE; COMORBIDITY; DISEASE ASSOCIATION; HEALTH CARE ORGANIZATION; HUMAN; LETTER; PRIORITY JOURNAL; RISK ASSESSMENT; COMMUNICABLE DISEASE; DRUG ANTAGONISM; NOTE; PSEUDOMEMBRANOUS COLITIS; RISK; UNITED KINGDOM;

ANTI-BACTERIAL AGENTS; CLOSTRIDIUM DIFFICILE; COMMUNITY-ACQUIRED INFECTIONS; COMORBIDITY; ENTEROCOLITIS, PSEUDOMEMBRANOUS; GASTROINTESTINAL AGENTS; H(+)-K(+)-EXCHANGING ATPASE; HISTAMINE H2 ANTAGONISTS; HUMANS; RISK; CLOSTRIDIUM INFECTIONS; GREAT BRITAIN;

EID: 33745102785     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.295.22.2599-b     Document Type: Letter

References (5)

1. Dial S, Delaney JA, Barkun AN, Suissa S. Use of gastric acid-suppressive agents and the risk of community-acquired Clostridium difficile-associated disease. JAMA. 2005;294:2989-2995.
2. Hirschhorn LR, Trnka Y, Onderdonk A, Lee ML, Platt R. Epidemiology of community-acquired Clostridium difficile-associated diarrhea. J Infect Dis. 1994;169:127-133.
3. Noren T, Akerlund T, Back E, et al. Molecular epidemiology of hospitalassociated and community-acquired Clostridium difficile infection in a Swedish county. J Clin Microbiol. 2004;42:3635-3643.
4. Pepin J, Saheb N, Coulombe MA, et al. Emergence of fluoroquinolones as the predominant risk factor for Clostridium difficile-associated diarrhea: a cohort study during an epidemic in Quebec. Clin Infect Dis. 2005;41:1254-1260.
5. Kyne L, Sougioultzis S, McFarland LV, Kelly CP. Underlying disease severity as a major risk factor for nosocomial Clostridium difficile diarrhea. Infect Control Hosp Epidemiol. 2002;23:653-659.