A chemogenomic approach to discovering target-selective drugs

Chemical Biology and Drug Design

Volumn 67, Issue 1, 2006, Pages 85-86

  Janzen, William P ^a   Hodge, C Nicholas ^a  

^a Amphora Discovery Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ION CHANNEL;

ACCURACY; ALGORITHM; DATA BASE; DRUG DESIGN; DRUG TARGETING; GENOME; HIGH THROUGHPUT SCREENING; MOLECULE; PHARMACOGENOMICS; PRIORITY JOURNAL; SHORT SURVEY;

CHEMISTRY, PHARMACEUTICAL; DATABASES, PROTEIN; DRUG DESIGN; STRUCTURE-ACTIVITY RELATIONSHIP; TECHNOLOGY, PHARMACEUTICAL;

EID: 33745093139     PISSN: 17470277     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2005.00325.x     Document Type: Short Survey

References (3)

1. Janzen W. Bernasconi P. Cheatham L. Mansky P. Popa-Burke I. Williams K. Worley J. Hodge N. ( 2004) Optimizing the chemical genomics process. In: Darvas X Guttman X Dorman X, editors. Chemical Genomics: Advances in Drug Discovery and Functional Genomics Applications. New York : Marcel Dekker, p. 59 100
2. Popa-Burke I. Birkos S. Blackwell L. Cheatham L. Clark J. Dickson J.K. Galasinski S. Janzen W.P. Mendoza J. Miller J. Mohney R.P. Hodge C.N. ( 2005) Discovery of highly selective inhibitors of p38α. Curr Topics Med Chem 5 : 941 951.
3. Popa-Burke I.G. Issakova O. Arroway J.D. Bernasconi P. Chen M. Coudurier L. Galasinski S. Janzen W.P. Lagasca D. Liu D. Lewis R.S. Mohney R.P. Sepetov N. Sparkman D.A. Hodge C.N. ( 2004) Streamlined system for purifying and quantifying a diverse library of compounds and the effect of compound concentration measurements on the accurate interpretation of biological assay results. Anal Chem 76 : 7278 7287.