The vulva is relatively insensitive to menses-induced irritation

Cutaneous and Ocular Toxicology

Volumn 24, Issue 4, 2005, Pages 243-246

  Farage, Miranda ^a   Warren, Raphael ^a   Wang Weigand, Sherri ^b  

^a PROCTER AND GAMBLE COMPANY   (United States)

^b TAKEDA PHARMACEUTICALS   (United States)

Author keywords

Blood; Emollient; Erythema; Irritation; Labia majora; Menses; Occlusion; Patch test; Vulva

Indexed keywords

DODECYL SULFATE SODIUM; EMOLLIENT AGENT; PETROLATUM;

ARM; ARTICLE; BODY FLUID; COMPARATIVE STUDY; CONTROLLED STUDY; ERYTHEMA; FEMALE; HUMAN; MENSTRUATION; NORMAL HUMAN; SKIN IRRITATION; SKIN SENSITIVITY; SKIN TEST; TIME; VENOUS BLOOD; VULVA;

EID: 33745077969     PISSN: 15569527     EISSN: 15569535     Source Type: Journal    
DOI: 10.1080/15569520500371735     Document Type: Article

References (7)

1. Beller FK, Schweppe KW. eds. Review of the Biology of Menstrual Blood. New York: Elsevier/North Holland, 1979:231-235.
2. Marbaix E, Kokorine I, Moulin P, Donnez J, Eeckhout Y, Courtoy PJ. Menstrual breakdown of human endometrium can be mimicked in vitro and is selectively and reversibly blocked by inhibitors of matrix metalloproteinases. Proc Natl Acad Sci USA 1996; 93(17):9120-9125.
3. Britz MB, Maibach HI. Human cutaneous vulvar reactivity to irritants. Contact Dermatitis 1979; 5(6):375-377.
4. Elsner P, Wilhelm D, Maibach HI. Effect of low-concentration sodium lauryl sulfate on human vulvar and forearm skin. Age-related differences. J Reprod Med 1991; 36(1):77-81.
5. Patrick E, Maibach HI. Dermatotoxicology. In: Hayes AW, ed. Principles and Methods of Toxicology, 2nd ed. New York: Raven Press, 1989, Chapter 13, 383-406.
6. Phillips L. II, Steinberg M, Maibach HI, Akers WAA. A comparison of rabbit and human skin response to certain irritants. Toxicol Appl Pharmacol 1972; 21(3):369-382.
7. Elsner P, Wilhelm D, Maibach HI. Irritant effect of a model surfactant on the human vulva and forearm. Age-related differences. J Reprod Med 1990; 35(11):1035-1039.