Alterations of blood IL-8, TGF-β1 and nitric oxide levels in relation to blood cells in patients with acute brain injury

Therapy

Volumn 3, Issue 3, 2006, Pages 399-405

  Hadidi, Elham ^a   Mojtahedzadeh, Mojtaba ^b   Paknejad, Mohammad Hassan ^b   Nikfar, Shekoufeh ^c   Zamani, Mohammad Jafar ^d   Sahraian, Mohammad Ali ^b   Eftekhar, Behzad ^b   Khajavi, Mohammad R ^d   Najafi, Atabak ^d   Ghaffarzadeh, Mahtab ^b   Eftekhari, Righieh ^b   Soleimani, Venus ^b   Esmaily, Hadi ^d   Rouini, Mohammad Reza ^d   Abdollahi, Mohammad ^d  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c MINISTRY OF HEALTH AND MEDICAL EDUCATION   (Iran)

^d TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Acute brain injury; Biomarker; Cytokine; Interleukine; Nitric oxide; Transforming growth factor

Indexed keywords

INTERLEUKIN 8; NITRIC OXIDE; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; BLOOD CELL; BLOOD CELL COUNT; BRAIN INJURY; BRAIN TISSUE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DISEASE COURSE; FEMALE; HOMEOSTASIS; HUMAN; INFLAMMATION; LEUKOCYTE COUNT; MALE; PATHOPHYSIOLOGY; PREDICTION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SURVIVAL; THROMBOCYTE COUNT; TIME;

EID: 33745077358     PISSN: 14750708     EISSN: 1744831X     Source Type: Journal    
DOI: 10.2217/14750708.3.3.399     Document Type: Article

References (54)

1. Kochanek PM, Clark RS, Ruppel RA et al. Biochemical, cellular and molecular mechanisms in the evolution of secondary damage after severe traumatic brain injury in infants and children: lessons learned at the bedside. Pediatr. Crit. Care Med. 1, 4-19 (2000).
2. Morganti-Kossmann MC, Kossmann T. The immunology of brain injury. In: Immune Responses in the Nervous System (Molecular and Cellular Neurobiology Series). Rothwell N (Ed.) Oxford University Press, 159-187 (1995).
3. Baggiolini M, Walz A, Kunkel SL. Neutrophil activating peptide 1, interleukin-8, a novel cytokine that activates neutophils. J. Clin. Invest. 84, 1045-1049 (1989).
4. Colditz I, Zwahlen R, Dewald B, Baggiolini M. In vivo inflammatory activity of neutrophil activating factor by monomeric interleukin-8. Am. J. Pathol. 134, 755-760 (1989).
5. Huber AR, Kunkel SL, Todd RF, Weiss SJ. Regulation of transendothelial neutrophil migration by endogenous interleukin-8. Science 254(5028), 99-102 (1991).
6. Aloisi F, Care A, Borsellino G et al. Production of hemolymphopoietic cytokines (IL-6, IL-8, colony-stimulating factors) by normal human astrocytes in response to IL-1β, and tumor necrosis factor-α. J. Immunol. 149, 2358-2366 (1992).
7. Bazzoni F, Cassatella MA, Rossi F, Ceska M, Dewals B, Baggiolini M. Phagocytosing neutrophils produce and release high amounts of neutrophil-activating peptide 1/interleukin-8. J. Exp. Med. 173, 771-774 (1991).
8. Dinarello CA. The proinflammatory cytokines interleukin-1 and tumor necrosis factor and treatment of the septic shock syndrome. J. Infect. Dis. 163, 1177-1184 (1991).
9. Nitta T, Allegretta M, Okumura K, Okumura K, Sato K, Steinman L. Neoplastic and reactive human astrocytes express interleukin-8 gene. Neurosurg. Rev. 15, 203-207 (1992).
10. Rezaie A, Taghavi Bayat B, Abdollahi M. Biologic management of fistulizing crohn's disease. Intl. J. Pharmacol. 1(1), 17-24 (2005).
11. Afshari M, Larijani B, Rezaie A et al. Ineffectiveness of allopurinol in reduction of oxidative stress in diabetic patients; a randomized, double-blind placebo-controlled clinical trial. Biomed. Pharmacother. 58, 546-550 (2004).
12. Jahanshahi G, Motavasel V, Rezaie A, Hashtroudi AA, Daryani NE, Abdollahi M. Alterations in antioxidant power and levels of epidermal growth factor and nitric oxide in saliva a of patients with inflammatory bowel diseases. Dig. Dis. Sci. 49(11-12), 1752-1757 (2004).
13. Salari P, Mojtahedzadeh M, Najafi A et al. Comparison of the effect of aminophylline and low PEEP vs. high PEEP on EGF concentration in critically ill patients with ALI/ARDS. J. Clin. Pharm. Ther. 30, 139-144 (2005).
14. Zamani MJ, Sharifzadeh M, Rezaie A, Mashayekhi F, Abdollahi M. Effects of sildenafil on rat irritable bowel syndrome. Therapy 2(2), 237-242 (2005).
15. Vazin, A, Mojtahedzadeh M, Najafi A, Khalilzadeh A, Abdollahi M. Relationship between duration, fatality rate and severity of disease and serum epidermal growth factor in human acute lung injury. Therapy 2(2), 255-259 (2005).
16. Salari P, Mojtahedzadeh M, Abdollahi M. Influence of serum epidermal growth factor on mechanical ventilation and survival in patients with acute respiratory distress syndrome. Therapy 2(3), 393-398 (2005).
17. Mojtahedzadeh M, Vazin A, Najafi A, Khalilzadeh A, Abdollahi M. The effect of furosemide infusion on serum epidermal growth factor concentration after acute lung injury. J. Infus. Nurs. 28(3), 188-193 (2005).
18. Astaneie F, Afshari M, Mojtahedi A et al. Total antioxidant capacity and levels of epidermal growth factor and nitric oxide in blood and saliva of insulin dependent diabetic patients. Arch. Med. Res. 36(4), 376-381 (2005).
19. Radfar M, Larijani B, Hadjibabaie M, Rajabipour B, Mojtahedi A, Abdollahi M. Effects of pentoxifylline on oxidative stress and levels of EGF and NO in blood of diabetic Type-2 patients; a randomized, double-blind placebo-controlled clinical trial. Biomed. Pharmacother. 59, 302-306 (2005).
20. Rezaie S, Rezaie A, Minaiee B, Khorasani R, Abdollahi M. On the relation of nitric oxide to nifedipine-induced gingival hyperplasia and impaired submandibular glands function in rats in vivo. Fundam. Clin. Pharm. 19(1), 65-71 (2005).
21. Tsuchihashi Y, Kitamura T, Fujita S. Immunofluorescence studies of the monocytes in the injured rat brain. Acta. Neuropathol (Berl). 53(3), 213-219 (1981).
22. Giulian D, Chen J, Ingeman JE, George Jk, Noponen M. The role of mononuclear phagocytes in wound healing after traumatic injury to adult mammalian brain. J. Neurosci. 9, 4416-4429 (1989).
23. Hickey W, Hsu B, Kimura H. T-lymphocyte entry into the central nervous system. J. Neurol. Sci. 28(12), 254-260 (1991).
24. Alevizopoulus A, Mermod N. Transforming growth factor-β: the breaking open of a black box. Bioessays. 19, 581-591 (1997).
25. Wahl SM, Hunt DA, Wakefield LM et al. Transforming growth factor β induces monocyte chemotaxis arid growth factor production. Proc. Natl Acad. Sci. USA 84, 5788-5792 (1987).
26. Ulich TR, Yin S, Guo K, Yi E, Remick D, del Castillo J. Intratracheal injection of endotoxin and cytokines: interleukin-6 and transforming growth factor β inhibit acute inflammation. Am. J. Pathol. 138, 1097-1101 (1991).
27. da Cunha A, Jefferson J, Jackson RW, Vitkovic L. Glial cell-specific mechanisms of TGF-β1 induction by IL-1 in cerebral cortex. J. Neuroimmunol. 42, 71-86 (1993).
28. Morganti-Kossmann MC, Kossmann T, Brandes ME, Mergenhagen SE, Wahl SM. Autocrine and paracrine regulation of astrocyte function by transforming growth factor β. J. Neuroimmunol. 39, 163-174 (1992).
29. Morgan TE, Nichols NR, Pasinetti GM, Finch CE. TGF-β1 mRNA increases in macrophage/microglial cells of the hippocampus in response to deafferentation and kainic acid-induced neurodegeneration. Exp. Neurol. 120, 291-301 (1993).
30. Wahl SM, McCartney-Francis N, Mergenhagen SE. Inflammatory and immunomodulatory roles of TGF-β. Immunol. Today 10, 258-261 (1989).
31. Wahl SM. Transforming growth factor β (TGF-β) in inflammation: a cause and a cure. J. Clin. Immunol. 12, 61-74 (1992).
32. Benveniste EN, Tang LP, Law RM. Differential regulation of astrocyte TNF-α expression by the cytokines TGF-β, IL-6 and IL-10. Int. J. Dev. Neurosci. 13, 341-349 (1995).
33. Attisano L, Wrana JL. Signal transduction by the TGF-β superfamily. Science 296, 1646-1647 (2002).
34. Fabry Z, Waldschmidt MM. Hendrickson D et al. Adhesion molecules on murine brain microvascular endothelial cells: expression and regulation of ICAM-1 and Lgp 55. J. Neuroimmunol. 36. 1-11 (1992).
35. Fabry Z, Topham DJ, Fee D et al. TGF-β 2 decreases migration of lymphocytes in vitro and homing of cells into the central nervous system in vivo. J Immunol. 155, 325-332 (1995).
36. Lawrence DA. Transforming growth factor-β: a general review. Eur. Cytokine. Netw. 17, 363-374 (1996).
37. Prehn JH, Bindokas V, Marcucilli C, Krajewski S, Reed J, Miller R. Regulation of neuronal bcl2 protein expression and calcium homeostasis by transforming growth factor type β confers wide ranging protection on rat hippocampal neurons. Proc. Natl. Acad. Sci. USA 91, 12599-12603 (1994).
38. Fee DB, Sewell DL, Andresen K et al. Traumatic brain injury increases TGFβRII expression on endothelial cells. Brain Res. 1012 (1-2). 52-59 (2004).
39. Kim JS, Yoon SS, Kim YH, Ryu JS. Serial measurement of interleukin 6, transforming growth factor-β and S-100 protein in patients with acute stroke Stroke 27, 1553-1557 (1996).
40. Slevin M, Krupinsk, J, Slowik A, Kuma, P, Szczudlik A, Gaffney J. Serial measurement of vascular endothelial growth factor and transforming growth factor-β1 in serum of patients with acute ischemic stroke. Stroke 31(8), 1863-1870 (2000).
41. Kim JS, Yoon SS, Kim YH, Ryu JS. Serial measurement of interleukin-6, transforming growth factor-β, and S-100 protein in patients with acute stroke. Stroke 27(9), 1553-1557 (1996).
42. D'Erasmo E, Cell FS, Acca M, Mazzuoli G. Relationship between platelet and white blood cell counts during the early phase of cerebral infarction. Stroke 22, 283 (1991).
43. Kossmann T, Stahel PF, Lenzlinger PM et al. Interleukin-8 released into the cerebrospinal fluid after brain injury is associated with blood brain barrier dysfunction and nerve growth factor production. J. Cereb. Blood Flow Metab. 17, 280-289 (1997).
44. Araujo DM, Cotman CW. Trophic effects of interleukin-4, -7 and -8 on hippocampal neuronal cultures: potential involvement of glia-derived factors. Brain Res. 600, 49-55 (1993).
45. Lacy M, Jones J, Whittemore SR, Haviland DL, Wetsel RA, Barnum SR. Expression of the receptors for the C5a anaphylatoxin, interleukin-8 and FMLP by human astrocytes and microglia. J. Neuroimmunol. 61, 71-78 (1995).
46. Kossmann T, Stahel PF, Lenzlinger PM et al. Interleukin-8 released into the cerebrospinal fluid after brain injury is associated with blood-brain barrier dysfunction and nerve growth factor production. J. Cereb. Blood Flow Metab. 17(3), 280-289 (1997).
47. Kossmann T, Hans V, Imhof H-G et al. Interleukin-6 released in human cerebrospinal fluid following traumatic brain injury may trigger nerve growth factor pro-duction in astrocytes. Brain Res. 713, 143-152 (1996).
48. Ott L, McClain CJ, Gillespie M, Young B. Cytokines and metabolic dysfunction after severe head injury. J. Neurotrauma 11, 447-472 (1994).
49. Kostulas N, Kivisakk P, Huang Y et al. Ischemic stroke is associated with a systemic increase of blood mononuclear cells expressing interleukin-8 mRNA. Stroke 29(2), 462-466 (1998).
50. Whalen MJ, Carlos TM, Kochanek PM et al. Interleukin-8 is increased in CSF of children with severe head injury. Crit. Care Med. 28, 929-934 (2000).
51. Kossmann T, Hans VHJ, Imhof HG et al. Intrathecal and serum interleukin-6 and the acute-phase response in patients with traumatic brain injuries. Shock 4, 311-317 (1995).
52. Kushi H, Saito T, Makino K, Hayashi N. IL-8 is a key mediator of neuroinflammation in severe traumatic brain injuries. Acta Neurochir. Suppl. 86, 347-350 (2003).
53. Cherian L, Hlatky R, Robertson CS. Nitric oxide in traumatic brain injury. Brain Pathol. 14(2), 195-201 (2004).
54. Sinz EH, Kochanek PM, Dixon CE et al. Inducible nitric oxide synthases an endogenous neuroprotectant after traumatic brain injury in rats and mice. J. Clin. Invest. 104, 647-656 (1999).