Pulmonary arteriole remodeling in hypoxic broilers expressing different amounts of endothelial nitric oxide synthase

Poultry Science

Volumn 85, Issue 5, 2006, Pages 899-901

  Moreno De Sandino, M ^a   Hernandez A ^a  

^a UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

Author keywords

Broiler; Hypoxia; Nitric oxide; Pulmonary arteriole; Pulmonary hypertension; Vascular remodeling

Indexed keywords

ANIMALIA; GALLUS GALLUS;

NITRIC OXIDE SYNTHASE;

AGING; ANIMAL; ANIMAL DISEASE; ANOXIA; ARTICLE; BIRD DISEASE; CHICKEN; ENZYMOLOGY; LUNG CIRCULATION; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PULMONARY HYPERTENSION; VASCULAR ENDOTHELIUM;

AGING; ANIMALS; ANOXIA; CHICKENS; ENDOTHELIUM, VASCULAR; HYPERTENSION, PULMONARY; NITRIC OXIDE SYNTHASE; POULTRY DISEASES; PULMONARY CIRCULATION;

EID: 33745070945     PISSN: 00325791     EISSN: 15253171     Source Type: Journal    
DOI: 10.1093/ps/85.5.899     Document Type: Article

References (18)

1. Adnot, S., B. Rafestin, S. Eddahibi, P. Braquet, and P. Chabrier. 1991. Loss of endothelium-dependent relaxant activity in the pulmonary circulation of rats exposed to chronic hypoxia. J. Clin. Invest. 87:155-162.
2. Envetchakul, B., J. Beasley, and W. Bottje. 1995. Pulmonary arteriole hypertrophy in broilers with pulmonary hypertension syndrome (ascites). Poult. Sci. 74:1676-1682.
3. Horstman, D. J., D. U. Frank, and G. F. Rich. 1998. Prolonged inhaled NO attenuates hypoxic, but not monocrotaline-induced, pulmonary vascular remodelling in rats. Anesth. Analg. 86:74-81.
4. Mehta, S., D. J. Stewart, D. Langleben, and R. D. Levy. 1995. Short-term pulmonary vasodilation with L-arginine in pulmonary hypertension. Circulation 92:1539-1545.
5. Mitani, Y., K. Maruyama, and M. Sakurai. 1997. Prolonged administration of L-arginine ameliorates chronic pulmonary hypertension and pulmonary vascular remodeling in rats. Circulation 96:689-697.
6. Montalvo, C., M. Ayon, and A. H. Sillau. 1979. Pages 16-22 in Histología de las Arteriolas Pulmonares en Aves a Nivel del Mar y en la Altura (3.300 Metros sobre el Nivel del Mar). Anales del Congreso Latinoamericano de Avicultura, Lima, Perú.
7. Moreno de Sandino, M., and A. Hernández. 2003. Nitric oxide synthase expression in the endothelium of pulmonary arterioles in normal and pulmonary hypertensive chickens subjected to chronic hypobaric hypoxia. Avian Dis. 47:1291-1297.
8. Pan, J. Q., J. C. Li, W. D. Sun, and X. L. Wang. 2005. Effects of early feed restriction and cold temperature on lipid peroxidation, pulmonary vascular remodelling and ascites morbidity in broilers under normal and cold temperatures. Br. Poult. Sci. 46:374-381.
9. Reid, L. M. 1979. The pulmonary circulation: Remodelling in growth and disease. Am. Rev. Respir. Dis. 56:531-546.
10. Roberts, J. D., C. T. Roberts, R. C. Jones, W. M. Zapol, and K. D. Bloch. 1995. Continuous nitric oxide inhalation reduces pulmonary arterial structural changes, right ventricular hypertrophy, and growth retardation in the hypoxic newborn rat. Circ. Res. 76:215-222.
11. SAS Institute. 1985. SAS® User's Guide. Version 5 Edition. SAS Inst., Inc., Cary, NC.
12. Sillau, A. H., and C. Montalvo. 1982. Pulmonary hypertension and the smooth muscle of the pulmonary arterioles in chickens at high altitude. Comp. Biochem. Physiol. Part A Physiol. 71:125-130.
13. Stenmark, K. R., and R. P. Mecham. 1997. Cellular and molecular mechanisms of pulmonary vascular remodeling. Annu. Rev. Physiol. 59:89-144.
14. Tan, X., J. Q. Pan, J. C. Li, Y. J. Liu, W. D. Sun, and X. L. Wang. 2005. L-arginine inhibiting pulmonary vascular remodelling is associated with promotion of apoptosis in pulmonary arterioles smooth muscle cells in broilers. Res. Vet. Sci. 79:203-209.
15. Tucker, A., I. F. Mcmurtry, A. F. Alexander, J. T. Reeves, R. F. Grover, and D. H. Alexander. 1975. Lung vascular smooth muscle as a determinant of pulmonary hypertension at high altitude. Am. J. Physiol. 228:762-767.
16. Wideman, R. F., Y. K. Kirby, M. Ismail, W. G. Bottje, R. W. Moore, and R. C. Vardeman. 1995. Supplemental L-arginine attenuates pulmonary hypertension syndrome in broilers. Poult. Sci. 74:323-330.
17. Xiang, R. P., W. D. Sun, J. Y. Wang, and X. L. Wang. 2002. Effect of vitamin C on pulmonary hypertension and muscularisation of pulmonary arterioles in broilers. Br. Poult. Sci. 43:705-712.
18. Xiang, R. P., W. D. Sun, K. C. Zhang, J. C. Li, J. Y. Wang, and X. L. Wang. 2004. Sodium chloride-induced acute and chronic pulmonary hypertension syndrome in chickens. Poult. Sci. 83:732-736.