Vancomycin-induced elevation of liver enzyme levels

Annals of Pharmacotherapy

Volumn 40, Issue 6, 2006, Pages 1186-1189

  Cadle, Richard M ^a,b   Mansouri, Mohammad D ^a   Darouiche, Rabih O ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Bioavailability; Liver enzymes; Vancomycin

Indexed keywords

ACETYLSALICYLIC ACID; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; AZITHROMYCIN; BACLOFEN; CEFEPIME; COLESTYRAMINE; DOCUSATE SODIUM; DOPAMINE; FLUOXETINE; FOLIC ACID; HYDROCODONE; INSULIN; LEVOTHYROXINE; LIVER ENZYME; METOPROLOL; METRONIDAZOLE; NITAZOXANIDE; OXYBUTYNIN; PARACETAMOL; PIPERACILLIN PLUS TAZOBACTAM; THIAMINE; VANCOMYCIN;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC THERAPY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BACTEREMIA; BLOOD CELL COUNT; CASE REPORT; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLOSTRIDIUM DIFFICILE; COMPUTER ASSISTED TOMOGRAPHY; CONGESTIVE HEART FAILURE; DECUBITUS; DEPRESSION; DIABETES MELLITUS; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG WITHDRAWAL; ENTEROCOLITIS; EPIDURAL ABSCESS; GRAM POSITIVE BACTERIUM; HUMAN; HYPOTHYROIDISM; INFECTIOUS DIARRHEA; LIVER DYSFUNCTION; LIVER TOXICITY; MALE; NEUROGENIC BLADDER; PHYSICAL EXAMINATION; PNEUMONIA; PRIORITY JOURNAL; QUADRIPLEGIA; SIGMOIDOSCOPY; THORAX RADIOGRAPHY; URINARY TRACT INFECTION;

ALANINE TRANSAMINASE; ANTI-BACTERIAL AGENTS; ASPARTATE AMINOTRANSFERASES; CLOSTRIDIUM DIFFICILE; DIARRHEA; DRUG RESISTANCE; ENTEROCOLITIS, PSEUDOMEMBRANOUS; HUMANS; LIVER; LIVER FUNCTION TESTS; MALE; METRONIDAZOLE; MIDDLE AGED; VANCOMYCIN;

EID: 33745066455     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1G668     Document Type: Article

References (16)

1. Malnick SD, Zimhony O. Treatment of Clostridium difficile-associated diarrhea. Arm Pharmacother 2002;36:1767-75. DOI 10.1345/aph.1A160
2. Fekety R, Siva J, Kauffman C, Buggy B, Deery HG. Treatment of antibiotic-associated Clostridium difficile colitis with oral vancomycin: comparison of two dosage regimens. Am J Med 1989;86:15-9.
3. Wilhelm MP, Estes L. Vancomycin. Mayo Clin Proc 1999;74:928-35.
4. Elting LS, Rubenstein EB, Kurtin D, et al. Mississippi mud in the 1990s: risks and outcomes of vancomycin-associated toxicity in general oncology practice. Cancer 1998;83:2597-607.
5. Naranjo CA, Busto U, Sellers EM, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239-45.
6. Currie BP, Lemos-Filho L. Evidence for biliary excretion of vancomycin into stool during intravenous therapy: potential implications for rectal colonization with vancomycin-resistant enterococci. Antimicrob Agents Chemother 2004;48:4427-9.
7. Lucas RA, Bowtle WJ, Ryden R. Disposition of vancomycin in healthy volunteers from oral solution and semi-solid matrix capsules. J Clin Pharm Ther 1987;12:27-31.
8. Thompson CM, Long SS, Gilligan PH. Absorption of oral vancomycin: possible associated toxicity. Int J Pediatr Nephrol 1983;4:1-4.
9. Spitzer PG, Eliopoulos GM. Systemic absorption of enteral vancomycin in a patient with pseudomembranous colitis. Ann Intern Med 1984;100:533-4.
10. Cook FV, Farrar WE. Vancomycin revisited. Ann Intern Med 1978;88:813-8.
11. Bryan CS, White WL. Safety of oral vancomycin in functionally anephric patients. Antimicrob Agents Chemother 1978;14:634-5.
12. Bergeron L, Boucher FD. Possible red-man syndrome associated with systemic absorption of oral vancomycin in a child with normal renal function. Ann Pharmacother 1994;28:581-4.
13. Guerriero SE, Ehrenpreis E, Gallagher KL. Two cases of clarithromycin-induced digoxin toxicity. Pharmacotherapy 1997;17:1035-7.
14. Lindenbaum J, Rund DG, Butler VP Jr, Tse-Eng D, Saha JR. Inactivation of digoxin by the gut flora: reversal by antibiotic therapy. N Engl J Med 1981;305:789-94.
15. Davidsson L, Walczyk T, Morris A, Hurrell RF. Influence of ascorbic acid on iron absorption from an iron-fortified chocolate-flavored milk drink in Jamaican children. Am J Clin Nutr 1998;67:873-7.
16. Sakurai T, Hajiro K, Takakuwa H, Nishi A, Aihara M, Chiba T. Liver abscess caused by Clostridium difficile. Scand J Infect Dis 2001;33:69-70.