Angiotensin-converting enzyme DD genotype is preventive against circulatory failure in very-low-birthweight neonates

Acta Paediatrica, International Journal of Paediatrics

Volumn 95, Issue 6, 2006, Pages 747-750

  Nobilis, András ^a   Szabó, Miklós ^a   Kocsis, István ^a   Sulyok, Endre ^b   Tulassay, Tivadar ^c   Vásárhelyi, Barna ^c,d  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b Hungarian Academy of Sciences   (Hungary)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^d First Department of Pediatrics   (Hungary)

Author keywords

Angiotensin converting enzyme; Circulatory failure; Genetic polymorphism; Preterm infant

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

ARTICLE; CLINICAL ARTICLE; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HEART MUSCLE ISCHEMIA; HUMAN; INFANT; MALE; NEWBORN; PERINATAL PERIOD; PREMATURITY; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RISK FACTOR; VERY LOW BIRTH WEIGHT;

FEMALE; GENOTYPE; HUMANS; INFANT, NEWBORN; INFANT, VERY LOW BIRTH WEIGHT; MALE; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC; SHOCK;

EID: 33745064483     PISSN: 08035253     EISSN: 16512227     Source Type: Journal    
DOI: 10.1080/08035250500453256     Document Type: Article

References (17)

1. Seri I, Evans J. Controversies in the diagnosis and management of hypotension in the newborn infant. Curr Opin Pediatr 2001;13:116-23.
2. Sulyok E. Endocrine factors in the neonatal adaptation. Acta Physiol Hung 1989;74:329-39.
3. Yosipiv IV, Dipp S, El-Dahr SS. Ontogeny of somatic angiotensin- converting enzyme. Hypertension 1994;23:369-74.
4. Gomez RA, Tufro-McReddie A, Everett AD, Pentz ES. Ontogeny of renin and AT1 receptor in the rat. Pediatr Nephrol 1993;7:635-8.
5. Duncan JA, Scholey JW, Miller JA. Angiotensin II type 1 receptor gene polymorphisms in humans: physiology and pathophysiology of the genotypes. Curr Opin Nephrol Hypertens 2001;10:111-6.
6. Treszl A, Szabo M, Dunai G, Nobilis A, Kocsis I, Machay T, et al. Angiotensin II type 1 receptor A1166C polymorphism and prophylactic indomethacin treatment induced ductus arteriosus closure in very low birth weight neonates Pediatr Res 2003;54:753-5.
7. Agerholm-Larsen B, Tybjserg-Hansen A, Schnohr P, Nordestgaard BG. ACE gene polymorphism explains 30-40% of variability in serum ACE activity in both women and men in the population at large: the Copenhagen City Heart Study. Atherosclerosis 1999;147:425-7.
8. Nobilis A, Kocsis I, Tóth-Heyn P, Treszl A, Schuler A, Tulassay T, et al. Variance of ACE and AT1 receptor gene do not influence the risk of neonatal acute renal failure. Ped Nephrol 2001;16:1063-6.
9. Mello G, Parretti E, Gensini F, Sticchi E, Mecacci F, Scarselli G, et al. Maternal-fetal flow, negative events, and preeclampsia: role of ACE I/D polymorphism. Hypertension 2003;41:932-7.
10. Gurdol F, Isbilen E, Yilmaz H, Isbir T, Dirican A. The association between preeclampsia and angiotensin-converting enzyme insertion/deletion polymorphism. Clin Chim Acta 2004;341:127-31.
11. Bouba I, Makrydimas G, Kalaitzidis R, Lolis DE, Siamopoulos KC, Georgiou I. Interaction between the polymorphisms of the renin-angiotensin system in preeclampsia. Eur J Obstet Gynecol Reprod Biol 2003;110:8-11.
12. Szolnoki Z, Somogyvari F, Kondacs A, Szabo M, Fodor L, Bene J, et al. Evaluation of the modifying effects of unfavourable genotypes on classical clinical risk factors for ischaemic stroke. J Neurol Neurosurg Psychiatry 2003;74:1615-20.
13. Kajantie E, Rautanen A, Kere J, Andersson S, Yliharsila H, Osmond C, et al. The effects of the ACE gene insertion/deletion polymorphism on glucose tolerance and insulin secretion in elderly people are modified by birth weight. J Clin Endocrinol Metab 2004;89:5738-41.
14. Harding D, Dhamrait S, Marlow N, Whitelaw A, Gupta S, Humphries S, et al. Angiotensin-converting enzyme DD genotype is associated with worse perinatal cardiorespiratory adaptation in preterm infants. J Pediatr 2003;143:746-9.
15. Norwood VF, Fernandez LG, Tufro A, Gomez RA. Development of the renin-angiotensin system. In: Polin RA, Fox WW, Amban SH, editors. Fetal and neonatal physiology, 3rd ed. Philadelphia: Saunders; 2004. p. 1249-55.
16. Baudin B. Angiotensin II receptor polymorphisms in hypertension. Pharmacogenomic considerations. Pharmacogenomics 2002;3:65-73.
17. Guba M, Steinbauer M, Buchner M, Frolich D, Farkas S, Jauch KW, et al. Differential effects of short-term ACE-and AT1-receptor inhibition on postischaemic injury and leukocyte adherence in vivo and in vitro. Shock 2000;13:190-6.