Small for gestational age and the metabolic syndrome: Which mechanism is suggested by epidemiological and clinical studies?

Hormone Research

Volumn 65, Issue SUPPL. 3, 2006, Pages 123-130

  Levy Marchal C ^a   Czernichow, P ^a  

^a HÔPITAL ROBERT DEBRÉ   (France)

Author keywords

Adipose tissue; Catch up growth; Insulin resistance; Intrauterine growth retardation; Type 2 diabetes

Indexed keywords

ADIPONECTIN; INSULIN; LEPTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

ADIPOSE TISSUE; BODY COMPOSITION; BODY MASS; CATCH UP GROWTH; CONFERENCE PAPER; ENVIRONMENTAL FACTOR; FETAL MALNUTRITION; GENETIC SUSCEPTIBILITY; GESTATIONAL AGE; GLUCOSE TRANSPORT; HORMONE ACTION; HORMONE RELEASE; HUMAN; INSULIN RELEASE; INSULIN RESISTANCE; INTRAUTERINE GROWTH RETARDATION; LOW BIRTH WEIGHT; METABOLIC DISORDER; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL; PROTEIN FUNCTION; RISK FACTOR; BIRTH WEIGHT; CLINICAL TRIAL; EPIDEMIOLOGY; METABOLIC SYNDROME X; NEWBORN; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW; SECRETION; SMALL FOR DATE INFANT;

BIRTH WEIGHT; BODY COMPOSITION; CLINICAL TRIALS; DIABETES MELLITUS, TYPE 2; EPIDEMIOLOGIC STUDIES; HUMANS; INFANT, NEWBORN; INFANT, SMALL FOR GESTATIONAL AGE; INSULIN; METABOLIC SYNDROME X;

EID: 33745037809     PISSN: 03010163     EISSN: None     Source Type: Journal    
DOI: 10.1159/000091517     Document Type: Conference Paper

References (31)

1. Barker DJ, Winter PD, Osmond C, Margetts B, Simmonds SJ: Weight in infancy and death from ischaemic heart disease. Lancet 1989;2:577-580.
2. Hales CN, Barker DJ, Clark PM, Cox LJ, Fall C, Osmond C, Winter PD: Fetal and infant growth and impaired glucose tolerance at age 64. BMJ 1991;303:1019-1022.
3. Lithell HO, McKeigue PM, Berglund L, Mohsen R, Lithell UB, Leon DA: Relation of size at birth to non-insulin dependent diabetes and insulin concentrations in men aged 50-60 years. BMJ 1996;312:406-410.
4. McCance DR, Pettitt DJ, Hanson RL, Jacobsson LT, Knowler WC, Bennett PH: Birth weight and non-insulin dependent diabetes: thrifty genotype, thrifty phenotype, or surviving small baby genotype? BMJ 1994;308:942-945.
5. Hales CN, Desai M, Ozanne SE: The Thrifty Phenotype hypothesis: how does it look after 5 years? Diabet Med 1997;14:189-195.
6. Phillips DI, Barker DJ, Hales CN, Hirst S, Osmond C: Thinness at birth and insulin resistance in adult life. Diabetologia 1994;37:150-154.
7. Jaquet D, Gaboriau A, Czernichow P, Levy-Marchal C: Insulin resistance early in adulthood in subjects born with intrauterine growth retardation. J Clin Endocrinol Metab 2000;85:1401-1406.
8. Flanagan DE, Moore VM, Godsland IF, Cockington RA, Robinson JS, Phillips DI: Fetal growth and the physiological control of glucose tolerance in adults: a minimal model analysis. Am J Physiol Endocrinol Metab 2000;278:E700-E706.
9. Bavdekar A, Yajnik CS, Fall CH, Bapat S, Pandit AN, Deshpande V, Bhave S, Kellingray SD, Joglekar C: Insulin resistance syndrome in 8-year-old Indian children: small at birth, big at 8 years, or both? Diabetes 1999;48:2422-2429.
10. Beringue F, Blondeau B, Castellotti MC, Breant B, Czernichow P, Polak M: Endocrine pancreas development in growth-retarded human fetuses. Diabetes 2002;51:385-391.
11. Phipps K, Barker DJ, Hales CN, Fall CH, Osmond C, Clark PM: Fetal growth and impaired glucose tolerance in men and women. Diabetologia 1993;36:225-228.
12. Hofman PL, Cutfield WS, Robinson EM, Bergman RN, Menon RK, Sperling MA, Gluckman PD: Insulin resistance in short children with intrauterine growth retardation. J Clin Endocrinol Metab 1997;82:402-406.
13. Veening MA, Van Weissenbruch MM, Delemarre-Van De Waal HA: Glucose tolerance, insulin sensitivity, and insulin secretion in children born small for gestational age. J Clin Endocrinol Metab 2002;87:4657-4661.
14. Jaquet D, Deghmoun S, Chevenne D, Collin D, Czernichow P, Levy-Marchal C: Dynamic change in adiposity from fetal to postnatal life is involved in the metabolic syndrome associated with reduced fetal growth. Diabetologia 2005;48:849-855.
15. Léger J, Levy-Marchal C, Bloch J, Pinet A, Chevenne D, Porquet D, Collin D, Czernichow P: Reduced final height and indications for insulin resistance in 20 year olds born small for gestational age: regional cohort study. BMJ 1997;315:341-347.
16. Soto N, Bazaes RA, Pena V, Salazar T, Avila A, Iniguez G, Ong KK, Dunger DB, Mericq MV: Insulin sensitivity and secretion are related to catch-up growth in small-for-gestational-age infants at age 1 year: results from a prospective cohort. J Clin Endocrinol Metab 2003;88:3645-3650.
17. Yajnik CS, Fall CH, Vaidya U, Pandit AN, Bavdekar A, Bhat DS, Osmond C, Hales CN, Barker DJ: Fetal growth and glucose and insulin metabolism in four-year-old Indian children. Diabet Med 1995;12:330-336.
18. Yajnik CS, Lubree HG, Rege SS, Naik SS, Deshpande JA, Deshpande SS, Joglekar CV, Yudkin JS: Adiposity and hyperinsulinemia in Indians are present at birth. J Clin Endocrinol Metab 2002;87:5575-5580.
19. Whincup PH, Cook DG, Adshead F, Taylor SJ, Walker M, Papacosta O, Alberti KG: Childhood size is more strongly related than size at birth to glucose and insulin levels in 10-11-year-old children. Diabetologia 1997;40:319-326.
20. Barker DJ, Hales CN, Fall CH, Osmond C, Phipps K, Clark PM: Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth. Diabetologia 1993;36:62-67.
21. Valdez R, Athens MA, Thompson GH, Bradshaw BS, Stern MP: Birthweight and adult health outcomes in a biethnic population in the USA. Diabetologia 1994;37:624-631.
22. Dunger DB, Ong KK, Huxtable SJ, Sherriff A, Woods KA, Ahmed ML, Golding J, Pembrey ME, Ring S, Bennett ST, Todd JA: Association of the INS VNTR with size at birth. ALSPAC Study Team. Avon Longitudinal Study of Pregnancy and Childhood. Nat Genet 1998;19:98-100.
23. Lindsay RS, Hanson RL, Wiedrich C, Knowler WC, Bennett PH, Baier LJ: The insulin gene variable number tandem repeat class I/III polymorphism is in linkage disequilibrium with birth weight but not Type 2 diabetes in the Pima population. Diabetes 2003;52:187-193.
24. Eriksson JG, Forsen T, Tuomilehto J, Winter PD, Osmond C, Barker DJ: Catch-up growth in childhood and death from coronary heart disease: longitudinal study. BMJ 1999;318:427-431.
25. Dulloo AG: Regulation of fat storage via suppressed thermogenesis: a thrifty phenotype that predisposes individuals with catch-up growth to insulin resistance and obesity. Horm Res 2006;65(suppl 3):88-95.
26. Lapillonne A, Braillon P, Claris O, Chatelain PG, Delmas PD, Salle BL: Body composition in appropriate and in small for gestational age infants. Acta Paediatr 1997;86:196-200.
27. Petersen S, Gotfredsen A, Knudsen FU: Lean body mass in small for gestational age and appropriate for gestational age infants. J Pediatr 1988;113:886-889.
28. Ong K: Size at birth, postnatal growth and risk of obesity. Horm Res 2006;65(suppl 3):64-68.
29. Jaquet D, Gaboriau A, Czernichow P, Levy-Marchal C: Relatively low serum leptin levels in adults born with intra-uterine growth retardation. Int J Obes Relat Metab Disord 2001;25:491-495.
30. Boiko J, Jaquet D, Chevenne D, Rigal O, Czernichow P, Levy-Marchal C: In situ lipolytic regulation in subjects born small for gestational age. Int J Obes Relat Metab Disord 2005;29:565-570.
31. Jaquet D, Léger J, Czernichow P, Levy-Marchal C: The effect of in-utero undernutrition on the insulin resistance syndrome. Curr Diab Rep 2002;2:77-82.