Cefepime vs. Ampicillin/Sulbactam and Aztreonam as antibiotic prophylaxis in neurosurgical patients with external ventricular drain: Result of a prospective randomized controlled clinical trial

Journal of Clinical Pharmacy and Therapeutics

Volumn 31, Issue 3, 2006, Pages 231-235

  Wong, G K C ^a   Poon, W S ^a   Lyon, D ^a   Wai, S ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Antibiotic prophylaxis; Cerebrospinal fluid infection; External ventricular drain; Wound infection

Indexed keywords

AZTREONAM; CEFEPIME; SULTAMICILLIN;

ADOLESCENT; ADULT; AGED; ANTIBIOTIC PROPHYLAXIS; ANTIBIOTIC THERAPY; ARTICLE; CATHETER INFECTION; CEREBROSPINAL FLUID DRAINAGE; CEREBROSPINAL FLUID INFECTION; CHILD; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HUMAN; INFECTION; INFECTION COMPLICATION; INFECTION PREVENTION; INFECTION RATE; MAJOR CLINICAL STUDY; MALE; RANDOMIZED CONTROLLED TRIAL; STATISTICAL SIGNIFICANCE; SURGICAL PATIENT; TREATMENT OUTCOME; WOUND INFECTION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AMPICILLIN; ANTIBIOTIC PROPHYLAXIS; AZTREONAM; CEPHALOSPORINS; CHILD; CHILD, PRESCHOOL; DRUG COMBINATIONS; FEMALE; HUMANS; INFECTION; MALE; MIDDLE AGED; MONOBACTAMS; NEUROSURGICAL PROCEDURES; PENICILLINS; POSTOPERATIVE COMPLICATIONS; PROSPECTIVE STUDIES; TREATMENT OUTCOME; VENTRICULOPERITONEAL SHUNT;

EID: 33745033066     PISSN: 02694727     EISSN: 13652710     Source Type: Journal    
DOI: 10.1111/j.1365-2710.2006.00729.x     Document Type: Article

References (13)

1. Alleyne CH Hassan M Zabramski JM 2000 The efficacy and cost of prophylactic and periprocedural antibiotics in-patients with external ventricular drains. Neurosurgery, 47, 1124 1129.
2. Aucoin PJ Kotilainen HR Gantz NM Davidson R Kellogg P Stone B 1986 Intracranial pressure monitors: epidemiological study of risk factors and infections. American Journal of Medicine, 80, 369 376.
3. Hader WJ Steinbok P 2000 The value of routine cultures of the cerebrospinal fluid in-patients with external ventricular drains. Neurosurgery, 46, 1149 1155.
4. Holloway KL Barnes T Choi S et al. 1996 Ventriculostomy infections: the effects of monitoring duration and catheter exchange in 584 patients. Journal of Neurosurgery, 85, 419 426.
5. Mayhall CG Archer NH Lamb VA Spadora AC Baggett JW Ward JD Narayan RK 1984 Ventriculostomy-related infections: a prospective epidemiological study. New England Journal of Medicine, 310, 553 559.
6. Paramore CG Turner DA 1994 Relative risks of ventriculostomy infection and morbidity. Acta Neurochirurgica, 127, 79 84.
7. Poon WS Ng S Wai S 1998 CSF antibiotic prophylaxis for neurosurgical patients with ventriculostomy: a randomized study. Acta Neurochirurgica. Supplementum, 71, 146 148.
8. Rebuck JA Murry KR Rhoney DH Michael DB Coplin WM 2000 Infection related to intracranial pressure monitors in adults: analysis of risk factors and antibiotic prophylaxis. Journal of Neurology, Neurosurgery and Psychiatry, 69, 381 389.
9. Rosner MJ Becker DP 1976 ICP monitoring: complications and associated factors. Clinical Neurosurgery, 23, 494 519.
10. Rossi S Buzzi F Paparella A Mainini P Stocchetti N 1998 Complications and safety associated with ICP monitoring: a study of 542 patients. Acta Neurochirurgica. Supplementum, 71, 91 93.
11. Schultz M Moore K Foote AW 1993 Bacterial ventriculitis and duration of ventriculostomy catheter insertion. Journal of Neuroscience Nursing, 25, 158 164.
12. Winfield JA Rosenthal P Kanter RK Casella G 1993 Duration of intracranial pressure monitoring does not predict daily risk of infective complications. Neurosurgery, 33, 424 431.
13. Zhu XL Wong WK Yeung WM et al. 2001 A randomized, double blind comparison of ampicillin/sulbactam and ceftriaxone in the prevention of surgical site infection after neurosurgery. Clinical Therapeutics, 23, 1281 1291.