A role for hippocampal gastrin-releasing peptide receptors in extinction of aversive memory

NeuroReport

Volumn 17, Issue 9, 2006, Pages 935-939

  Luft, Tatiana ^a,b   Flores, Debora G ^a,c   Vianna, Monica R M ^e   Schwartsmann, Gilberto ^c,d   Roesler, Rafael ^a,c,d   Izquierdo, Ivan ^f  

^a Cellular and Molecular Neuropharmacology Research Group   (Brazil)

^b Institute for Basic Health Sciences   (Brazil)

^c Academic Hospital Research Center   (Brazil)

^d FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^e Faculty of Biosciences   (Pakistan)

^f PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Bombesin like receptors; Extinction; Gastrin releasing peptide receptor; Hippocampus; RC 3095

Indexed keywords

ANISOMYCIN; GASTRIN RELEASING PEPTIDE RECEPTOR; PROTEIN SYNTHESIS INHIBITOR; RC 3095;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AVOIDANCE BEHAVIOR; BRAIN FUNCTION; CONTROLLED STUDY; FEAR; HIPPOCAMPUS; MALE; MEMORY; MEMORY CONSOLIDATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SHOCK; TASK PERFORMANCE;

ANIMALS; ANISOMYCIN; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; BOMBESIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; EXTINCTION, PSYCHOLOGICAL; HIPPOCAMPUS; MALE; MEMORY; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; REACTION TIME; RECEPTORS, BOMBESIN; STATISTICS, NONPARAMETRIC; TIME FACTORS;

EID: 33745032298     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.wnr.0000221832.33717.48     Document Type: Article

References (25)

1. Myers KM, Davis M. Behavioral and neural analysis of extinction. Neuron 2002; 36:567-584.
2. Barad M. Fear extinction in rodents: basic insight to clinical promise. Curr Opin Neurobiol 2005; 15:710-715.
3. Cammarota M, Bevilaqua LR, Barros DM, Vianna MR, Izquierdo LA, Medina JH, et al. Retrieval and the extinction of memory. Cell Mol Neurobiol 2005; 25:465-474.
4. Milad MR, Rauch SL, Pitman RK, Quirk GJ. Fear extinction in rats: implications for human brain imaging and anxiety disorders. Biol Psychol 2006; [Epub ahead of print 10 February 2006].
5. Vianna MR, Szapiro G, McGaugh JL, Medina JH, Izquierdo I. Retrieval of memory for fear-motivated training initiates extinction requiring protein synthesis in the rat hippocampus. Proc Natl Acad Sci USA 2001; 98:12251-12254.
6. Szapiro G, Vianna MR, McGaugh JL, Medina JH, Izquierdo I. The role of NMDA glutamate receptors, PKA, MAPK, and CAMKII in the hippocampus in extinction of conditioned fear. Hippocampus 2003; 13:53-58.
7. Vianna MR, Igaz LM, Coitinho AS, Medina JH, Izquierdo I. Memory extinction requires gene expression in rat hippocampus. Neurobiol Learn Mem 2003; 79:199-203.
8. Fischer A, Sananbenesi F, Schrick C, Spiess J, Radulovic J. Distinct roles of hippocampal de novo protein synthesis and actin rearrangement in extinction of contextual fear. J Neurosci 2004; 24:1926-1962.
9. Vianna MR, Coitinho AS, Izquierdo I. Role of the hippocampus and amygdala in the extinction of fear-motivated learning. Curr Neurovasc Res 2004; 1:55-60.
10. Chen X, Garelick MG, Wang H, Lil V, Athos J, Storm DR. PI3 kinase signaling is required for retrieval and extinction of contextual memory. Nat Neurosci 2005; 8:925-931.
11. Corcoran KA, Desmond TJ, Frey KA, Maren S. Hippocampal inactivation disrupts the acquisition and contextual encoding of fear extinction. J Neurosci 2005; 25:8978-8987.
12. Power AE, Berlau DJ, McGaugh JL, Steward O. Anisomycin infused into the hippocampus fails to block 'reconsolidation' but impairs extinction: the role of re-exposure duration. Learn Mem 2006; 13:27-34.
13. Flood JF, Morley JE. Effects of bombesin and gastrin-releasing peptide on memory processing. Brain Res 1988; 460:314-322.
14. Shumyatsky GP, Tsvetkov E, Malleret G, Vronskaya S, Hatton M, Hampton L, et al. Identification of a signaling network in lateral nucleus of amygdala important for inhibiting memory specifically related to learned fear. Cell 2002; 111:905-918.
15. Roesler R, Meller CA, Kopschina MI, Souza DO, Henriques JA, Schwartsmann G. Intrahippocampal infusion of the bombesin/gastrin-releasing peptide antagonist RC-3095 impairs inhibitory avoidance retention. Peptides 2003; 24:1069-1074.
16. Santo-Yamada Y, Yamada K, Wada E, Goto Y, Wada K. Blockade of bombesin-like peptide receptors impairs inhibitory avoidance learning in mice. Neurosci Lett 2003; 340:65-68.
17. Roesler R, Kopschina MI, Rosa RM, Henriques JA, Souza DO, Schwartsmann G. RC-3095, a bombesin/gastrin-releasing peptide antagonist, impairs aversive but not recognition memory in rats. Eur J Pharmacol 2004; 486:35-41.
18. Roesler R, Lessa D, Venturella R, Vianna MR, Luft T, Henriques JA, et al. Bombesin/gastrin-releasing peptide receptors in the basolateral amygdala regulate memory consolidation. Eur J Neurosci 2004; 19:1041-1045.
19. Venturella R, Lessa D, Luft T, Roozendaal B, Schwartsmann G, Roesler R. Dexamethasone reverses the memory impairment induced by antagonism of hippocampal gastrin-releasing peptide receptors. Peptides 2005; 26:821-825.
20. Moody TW, Merali Z. Bombesin-like peptides and associated receptors within the brain: distribution and behavioral implications. Peptides 2004; 25:511-520.
21. Lee K, Dixon AK, Gonzalez I, Stevens EB, McNulty S, Oles R, et al. Bombesin-like peptides depolarize rat hippocampal interneurones through interaction with subtype 2 bombesin receptors. J Physiol 1999; 518:791-802.
22. Paxinos G, Watson C. The rat brain in stereotaxic coordinates. San Diego: Academic Press; 1997.
23. Kamichi S, Wada E, Aoki S, Sekiguchi M, Kimura I, Wada K. Immunohistochemical localization of gastrin-releasing peptide receptor in the mouse brain. Brain Res 2005; 1032:162-170.
24. Hellmich MR, Ives KL, Udupi V, Soloff MS, Greeley GH Jr, Christensen BN, et al. Multiple protein kinase pathways are involved in gastrin-releasing peptide receptor-regulated secretion. J Biol Chem 1999; 274:23901-23909.
25. Roesler R, Henriques JA, Schwartsmann G. Neuropeptides and anxiety disorders: bombesin receptors as novel therapeutic targets. Trends Pharmacol Sci 2004; 25:241-242.