Evaluation of antidiarrhoeal activity of the stem bark of Cylicodiscus gabunensis (mimosaceae)

African Journal of Biotechnology

Volumn 5, Issue 11, 2006, Pages 1062-1066

  Mabeku Kouitcheu, Laure B ^a   Penlap Beng, V ^a   Kouam, J ^a   Ngadjui, Bonaventure T ^a   Fomum, Z T ^a   Etoa, F X ^a  

^a UNIVERSITY OF YAOUNDÉ I   (Cameroon)

Author keywords

Antidiarrhoeal activity; Castor oil; Cylicodiscus gabunensis

Indexed keywords

ACETIC ACID ETHYL ESTER; ATROPINE; CASTOR OIL; CYLICODISCUS GABUNENSIS EXTRACT; LOPERAMIDE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BARK; CONTROLLED STUDY; DIARRHEA; DRUG ACTIVITY; DRUG MECHANISM; ELECTROLYTE METABOLISM; FEMALE; INTESTINE FLUID; INTESTINE TRANSIT TIME; MALE; MIMOSA; NONHUMAN; PLANT STEM; RAT;

CYLICODISCUS GABUNENSIS; FABACEAE;

EID: 33745031119     PISSN: 16845315     EISSN: 16845315     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Adjanohoun JE, Aboubakar N, Dramane K, Ebot ME, Ekpere JA, Enow-Orock EG (1996). Contribution to ethnobotanical and floristic studies in Cameroon. Traditional Medicine and Pharmacopoeia. Technical and Research Commission of Organisation of African Unity (OAU/STRC). pp. 241- 242.
2. Ammon PJ, Thomas, Philips S (1974). Effects of oleic and recinoleic acids net jejunal water and electrolyte movement. J. Clin. Invest. 53: 374- 379.
3. Anonymous (1962). The Wealth of India (Raw Material). CSIR, New Delhi, Vol. 6: 280- 281.
4. th edition, Macgrow Hill, New York.
5. Chudnoff M (1984).Tropical timbers of the World. USDA Forest Service. Ag. Handbook. p.607.
6. Doherty SS (1981) Inhibition of arachinodic acid release, mechanism by which glucocorticoids inhibit endotoxin-induced diarrhoea. British J. Pharmacol. 73: 549-554.
7. Fauci AS, Bravnwold E, Isselpacker K, Wilson JD, kasper DL, Hauser SL, Longo DL (1993). Harrison's Principles of Internal Medicine. New York, McGraw Hill Company. vol (1): 236 -242.
8. Galvez J, Zarzuelo A, Crespo ME (1991). Antidiarrhoeic activity of Scleroarya birrea bark extract and its active tannin constituent in rats. Phytother Res. 5: 276- 278.
9. Galvez J, Zarzuelo A, Crespo ME, Lorente MD, Ocete MA, Jimenez J (1993). Antidiarrhoeic activity of Euphorbia hirta extract and isolation of an active flavonoid constituent. Planta Medica 59: 333- 336.
10. th edition, MacGraw Hill, New York. pp. 914- 931.
11. Izzo AA, Mascolo N, Capasso R, Germano MP, De Pasquale R, Capasso F (1999). Inhibitory effect of cannabinoid agonists on gastric emptying in the rat. Achieves of Pharmacology. 360: 221-223.
12. Longanga Otshudi A, Vercruysse A, Foriers A (2000). Contribution to the ethnobotanical, phytochemical and pharmacological studies of traditionally used medicinal plant in the treatment of dysentery and diarrhoea in Lomela area, Democratic Republic of Congo (DRC). J Ethnopharmacol. 71(3): 411- 423.
13. Mujumdar AM (1998). Antidiarrhoeal activity of Azadiachta indica leaf extract. Indian Drugs 35 (7): 417- 420.
14. Odebeyi O, Sofowara EA (1978). Phytochemical screening. Nigeria medicinal plants. L. Coydia. 41: pp. 41- 234.
15. Park K (2000).Park's Textbook of preventive and social medicine. Jabalpur, India, M/S Banarsidas Bharat Publishes. pp. 172-175.
16. Robert A, Nezamis JF, Lancaster C, Hanchar AJ, Klepper MS (1976). Enteropooling assay: a test for diarrhoea produced by prostaglandins. Prostaglandins. 11: 809- 828.
17. Tchivounda HP, Koudogbo B, Besace Y, Casadevall E (1991).Triterpene saponins from Cylicodiscus gabunensis. Phytochemistry. 30(8): 2711- 2716.
18. Theoderau V, Fioramont J, Hachet T, Bueno L (1991). Absorptive and motor components of anti-diarrhoeal action of loperamide: an in vivo study in pigs. Gut. 32: 1355 - 1359.
19. Tripathi KD (1994). Essentials of Medical Pharmacology. Jaypee Brothers Medicals Publishers (P), New Delhi. p.775.
20. Watson WC, Gordon R (1962). Studies on the digestion absorption and metabolism of castol oil. Biochem. Pharmacol.11:229-236.
21. Zaval MA, Pera ZS, Perez P, Vargan R, Perz RM (1988). Antidiarrhoeal activity of Waltheria anorlana, Commelina coelestis and Alternanthera repens. J. Ethnopharmacol. 61: 41- 47.