Effects of improved metabolic control on platelet reactivity in patients with type 2 diabetes mellitus following coronary angioplasty

Diabetes and Vascular Disease Research

Volumn 3, Issue 1, 2006, Pages 52-56

  Yncen, Marianne ^a   Norhammar, Anna ^a   Hjemdahl, Paul ^a   Wallén, N Håkan ^b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b DANDERYD HOSPITAL   (Sweden)

Author keywords

Coronary angioplasty; Metabolic control; Platelet p selectin; Type 2 diabetes mellitus

Indexed keywords

ANTIDIABETIC AGENT; CLOPIDOGREL; HEMOGLOBIN A1C; INSULIN; PADGEM PROTEIN;

ADULT; AGED; ARTICLE; BLOOD CHEMISTRY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GLYCEMIC CONTROL; HUMAN; MALE; METABOLIC REGULATION; NON INSULIN DEPENDENT DIABETES MELLITUS; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; STATISTICAL ANALYSIS; THROMBOCYTE; TRANSLUMINAL CORONARY ANGIOPLASTY;

AGED; ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; BLOOD PRESSURE; DIABETIC ANGIOPATHIES; FEMALE; HEALTH STATUS; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INSULIN; MALE; MIDDLE AGED; P-SELECTIN; PLATELET ACTIVATION;

EID: 33745017446     PISSN: 14791641     EISSN: None     Source Type: Journal    
DOI: 10.3132/dvdr.2006.008     Document Type: Article

References (21)

1. Biondi-Zoccai GG, Abbate A, Liuzzo G et al. Atherothrombosis, inflammation, and diabetes. J Am Coll Cardiol 2003;41:1071-7.
2. Mathew V, Wilson SH, Barsness GW et al. Comparative outcomes of percutaneous coronary interventions in diabetics vs. non-diabetics with prior coronary artery bypass grafting. Fur Heart J 2002;23:1456-64.
3. Harjai KJ, Stone GW, Boura J et al. Comparison of outcomes of diabetic and nondiabetic patients undergoing primary angioplasty for acute myocardial infarction. Am J Cardiol 2003;91:1041-5.
4. Seven-year outcome in the Bypass Angioplasty Revascularization Investigation (BARI) by treatment and diabetic status. J Am Coll Cardiol 2000;35:1122-9.
5. Norhammar A, Malmberg K, Diderholm E et al. Diabetes mellitus: The major risk factor in unstable coronary artery disease even after consideration of the extent of coronary artery disease and benefits of revascularization. J Am Coll Cardiol 2004;43:585-91.
6. Aronson D, Bloomgarden Z, Rayfield EJ. Potential mechanisms promoting restenosis in diabetic patients. J Am Coll Cardiol 1996;2:528-35.
7. Reaven GM. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988;37:1595-607.
8. Colwell JA, Nesto RW. The platelet in diabetes: Focus on prevention of ischemic events. Diabetes Care 2003;26:2181-8.
9. Tschoepe D, Schultheiss HP, Kolarov P et al. Platelet membrane activation markers are predictive for increased risk of acute ischemic events after PTCA. Circulation 1993;88:37-42.
10. Kabbani SS, Watkins MW, Ashikaga T et al. Platelet reactivity characterized prospectively: A determinant of outcome 90 days after percutaneous coronary intervention. Circulation 2001;104:181-6.
11. Hannan EL, Kilburn H, Jr, O'Donnell JF et al. Adult open heart surgery in New York State. An analysis of risk factors and hospital mortality rates. JAMA 1990;264:2768-74.
12. Sobel BE. Potentiation of vasculopathy by insulin: Implications from an NHLBI Clinical Alert. Circulation 1996;93:1613-15.
13. McEver RP. Adhesive interactions of leukocytes, platelets, and the vessel wall during hemostasis and inflammation. Thromb Haemost 2001; 86:746-56.
14. Corpus RA, George PB, House JA et al. Optimal glycemic control is associated with a lower rate of target vessel revascularization in treated type II diabetic patients undergoing elective percutaneous coronary intervention. J Am Coll Cardiol 2004;43:8-14.
15. Muhlestein JB, Anderson JL, Horne BD et al. Effect of fasting glucose levels on mortality rate in patients with and without diabetes mellitus and coronary artery disease undergoing percutaneous coronary intervention. Am Heart J 2003;146:351-8.
16. Khaw KT, Wareham N, Bingham S et al. Association of hemoglobin A1c with cardiovascular disease and mortality in adults: The European Prospective Investigation into Cancer in Norfolk. Ann Intern Med 2004; 141:413-20.
17. Yngen M, Ostenson CG, Li N et al. Acute hyperglycemia increases soluble P-selectin in male patients with mild diabetes mellitus. Blood Coagul Fibrinolysis 2001;12:109-16.
18. Gresele P, Guglielmini G, De Angelis M et al. Acute, short-term hyperglycemia enhances shear stress-induced platelet activation in patients with type II diabetes mellitus. J Am Coll Cardiol 2003;41:1013-20.
19. Eibl N, Krugluger W, Streit G et al. Improved metabolic control decreases platelet activation markers in patients with type-2 diabetes. Eur J Clin Invest 2004;34:205-09.
20. Malmberg K. Prospective randomised study of intensive insulin treatment on long term survival after acute myocardial infarction in patients with diabetes mellitus. DIGAMI (Diabetes mellitus, Insulin Glucose infusion in Acute Myocardial Infarction) Study Group. BMJ 1997;314: 1512-15.
21. Malmberg K, Ryden L, Wedel H et al. Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): Effects on mortality and morbidity. Eur Heart J 2005;26:650-61.