Normal-phase chiral liquid chromatography-mass spectrometry of non-UV-active compounds: Applications for pharmaceutically relevant racemates

Journal of Chromatography A

Volumn 1120, Issue 1-2, 2006, Pages 82-88

  Kagan, M ^a   Chlenov, M ^a   Greenfield, A ^a   Ho, D M ^b  

^a PFIZER INC   (United States)

^b PRINCETON UNIVERSITY   (United States)

Author keywords

Absolute stereochemistry; Automatic purification; Camphorsultam; Chiral; Detection; Ethoxynonafluorobutane; LC MS; Non UV active; Normal phase

Indexed keywords

ALCOHOLS; BUTANE; DRUG PRODUCTS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEDICAL APPLICATIONS; MOLECULAR STRUCTURE;

ABSOLUTE STEREOCHEMISTRY; AUTOMATIC PURIFICATION; CAMPHORSULTAM; ETHOXYNONAFLUOROBUTANE; LC-MS; NON-UV-ACTIVE; NORMAL-PHASE;

ORGANIC COMPOUNDS;

1 (3 AMINOPROPYL) 2 PIPECOLINE; 10 CAMPHORSULFONAMIDE; 2 METHYLHEXANOIC ACID; 2,10 CAMPHORSULTAM; CAMPHOR DERIVATIVE; MUSCONE; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; CHIRAL CHROMATOGRAPHY; DRUG DETERMINATION; DRUG STRUCTURE; MASS SPECTROMETRY; PRIORITY JOURNAL; PURIFICATION; STEREOCHEMISTRY; STRUCTURE ANALYSIS; X RAY ANALYSIS;

BUTANES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOPARAFFINS; HYDROCARBONS, FLUORINATED; MOLECULAR STRUCTURE; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STEREOISOMERISM; ULTRAVIOLET RAYS;

EID: 33745008803     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2005.12.109     Document Type: Article

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