Angiotensinogen modulates renal vasculature growth

Hypertension

Volumn 47, Issue 6, 2006, Pages 1067-1074

  Brand, Marcus ^a   Lamandé, Noël ^a   Sigmund, Curt D ^b   Larger, Etienne ^a   Corvol, Pierre ^a   Gasc, Jean Marie ^a  

^a INSERM   (France)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Angiotensinogen; Animals, transgenic; Muscle, smooth, vascular; Remodeling; Vessels

Indexed keywords

ACTIN ANTIBODY; ALPHA ACTIN; ANGIOTENSIN II; ANGIOTENSINOGEN; PLATELET DERIVED GROWTH FACTOR RECEPTOR; RENIN; MESSENGER RNA;

ANIMAL CELL; ANIMAL TISSUE; ARTERIOLE; ARTERY WALL; ARTICLE; BLOOD VESSEL WALL; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; GROWTH; HUMAN; HUMAN CELL; HYPOPLASIA; IN SITU HYBRIDIZATION; KIDNEY; KIDNEY BLOOD VESSEL; MALE; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; TRANSGENIC MOUSE; TUNICA MEDIA; VASCULARIZATION; ANIMAL; APOPTOSIS; BLOOD VESSEL; C57BL MOUSE; CELL COUNT; CELL PROLIFERATION; CYTOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; HISTOLOGY; METABOLISM; PHYSIOLOGY; RENAL ARTERY; SMOOTH MUSCLE FIBER; TISSUE DISTRIBUTION; VASCULAR SMOOTH MUSCLE;

ANGIOTENSINOGEN; ANIMALS; APOPTOSIS; BLOOD VESSELS; CELL COUNT; CELL PROLIFERATION; FEMALE; HUMANS; KIDNEY; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; RENAL ARTERY; RNA, MESSENGER; TISSUE DISTRIBUTION;

EID: 33745003459     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000221065.05670.23     Document Type: Article

References (32)

1. Tewksbury DA. Angiotensinogen: biochemistry and molecular biology. In: Laragh JH, Brenner BM, eds. Hypertension. New York, NY: Raven Press; 1990:1197-1216.
2. Celerier J, Schmid G, Le Caer JP, Gimenez-Roqueplo AP, Bur D, Friedlein A, Langen H, Corvol P, Jeunemaitre X. Characterization of a human angiotensinogen cleaved in its reactive center loop by a proteolytic activity from Chinese hamster ovary cells. J Biol Chem. 2000;275:10648-10654.
3. Zhang M, Volpert O, Shi YH, Bouck N. Maspin is an angiogenesis inhibitor. Nat Med. 2000;6:196-199.
4. Dawson DW, Volpert OV, Gillis P, Crawford SE, Xu H, Benedict W, Bouck NP. Pigment epithelium-derived factor: a potent inhibitor of angiogenesis. Science. 1999;285:245-248.
5. Miao RQ, Agata J, Chao L, Chao J. Kallistatin is a new inhibitor of angiogenesis and tumor growth. Blood. 2002;100:3245-3252.
6. O'Reilly MS, Pirie-Shepherd S, Lane WS, Folkman J. Antiangiogenic activity of the cleaved conformation of the serpin antithrombin. Science. 1999;285:1926-1928.
7. Celerier J, Cruz A, Lamande N, Gasc JM, Corvol P. Angiotensinogen and its cleaved derivatives inhibit angiogenesis. Hypertension. 2002;39:224-228.
8. Bouquet C, Lamandé N, Brand M, Gasc J-M, Jullienne B, Faure G, Griscelli F, Opolon P, Connault E, Perricaudet M, Corvol P. Suppression of angiogenesis, tumor growth and metastasis by adenovirus-mediated gene transfer of human angiotensinogen. Mol Ther. In press.
9. Campbell DJ, Habener JF. Angiotensinogen gene is expressed and differentially regulated in multiple tissues of the rat. J Clin Invest. 1986;78:31-39.
10. Naftilan AJ, Zuo WM, Inglefinger J, Ryan TJ Jr, Pratt RE, Dzau VJ. Localization and differential regulation of angiotensinogen mRNA expression in the vessel wall. J Clin Invest. 1991;87:1300-1311.
11. Kakinuma Y, Hama H, Sugiyama F, Yagami K, Goto K, Murakami K, Fukamizu A. Impaired blood-brain barrier function in angiotensinogen-deficient mice. Nat Med. 1998;4:1078-1080.
12. Yanai K, Saito T, Kakinuma Y, Kon Y, Hirota K, Taniguchi-Yanai K, Nishijo N, Shigematsu Y, Horiguchi H, Kasuya Y, Sugiyama F, Yagami K, Murakami K, Fukamizu A. Renin-dependent cardiovascular functions and renin-independent blood-brain barrier functions revealed by renin-deficient mice. J Biol Chem. 2000;275:5-8.
13. Yang G, Merrill DC, Thompson MW, Robillard JE, Sigmund CD. Functional expression of the human angiotensinogen gene in transgenic mice. J Biol Chem. 1994;269:32497-32502.
14. Sibony M, Commo F, Callard P, Gasc JM. Enhancement of mRNA in situ hybridization signal by microwave heating. Lab Invest. 1995;73:586-591.
15. Clauser E, Bouhnik J, Jaramillo HN, Auzan C, Corvol P, Menard J. Angiotensinogen production and consumption in the adrenalectomized rat. Endocrinology. 1985;116:274-280.
16. Fuchs S, Germain S, Philippe J, Corvol P, Pinet F. Expression of renin in large arteries outside the kidney revealed by human renin promoter/LacZ transgenic mouse. Am J Pathol. 2002;161:717-725.
17. Menard J, Catt KJ. Measurement of renin activity, concentration and substrate in rat plasma by radioimmunoassay of angiotensin I. Endocrinology. 1972;90:422-430.
18. Tanimoto K, Sugiyama F, Goto Y, Ishida J, Takimoto E, Yagami K, Fukamizu A, Murakami K. Angiotensinogen-deficient mice with hypotension. J Biol Chem. 1994;269:31334-31337.
19. Kim HS, Krege JH, Kluckman KD, Hagaman JR, Hodgin JB, Best CF, Jennette JC, Coffman TM, Maeda N, Smithies O. Genetic control of blood pressure and the angiotensinogen locus. Proc Natl Acad Sci U S A. 1995;92:2735-2739.
20. Nagata M, Tanimoto K, Fukamizu A, Kon Y, Sugiyama F, Yagami K, Murakami K, Watanabe T. Nephrogenesis and renovascular development in angiotensinogen-deficient mice. Lab Invest. 1996;75:745-753.
21. Krege JH, John SW, Langenbach LL, Hodgin JB, Hagaman JR, Bachman ES, Jennette JC, O'Brien DA, Smithies O. Male-female differences in fertility and blood pressure in ACE-deficient mice. Nature. 1995;375:146-148.
22. Tsuchida S, Matsusaka T, Chen X, Okubo S, Niimura F, Nishimura H, Fogo A, Utsunomiya H, Inagami T, Ichikawa I. Murine double nullizygotes of the angiotensin type 1A and 1B receptor genes duplicate severe abnormal phenotypes of angiotensinogen nullizygotes. J Clin Invest. 1998;101:755-760.
23. Esther CR Jr, Howard TE, Marino EM, Goddard JM, Capecchi MR, Bernstein KE. Mice lacking angiotensin-converting enzyme have low blood pressure, renal pathology, and reduced male fertility. Lab Invest. 1996;74:953-965.
24. Hatae T, Takimoto E, Murakami K, Fukamizu A. Comparative studies on species-specific reactivity between renin and angiotensinogen. Mol Cell Biochem. 1994;131:43-47.
25. Fukamizu A, Sugimura K, Takimoto E, Sugiyama F, Seo MS, Takahashi S, Hatae T, Kajiwara N, Yagami K, Murakami K. Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human angiotensinogen genes. J Biol Chem. 1993;268:11617-11621.
26. Mazzolai L, Nussberger J, Aubert JF, Brunner DB, Gabbiani G, Brunner HR, Pedrazzini T. Blood pressure-independent cardiac hypertrophy induced by locally activated renin-angiotensin system. Hypertension. 1998;31:1324-1330.
27. Stouffer GA, Owens GK. Angiotensin II-induced mitogenesis of spontaneously hypertensive rat-derived cultured smooth muscle cells is dependent on autocrine production of transforming growth factor-β. Circ Res. 1992;70:820-828.
28. Langeveld B, van Gilst WH, Tio RA, Zijlstra F, Roks AJ. Angiotensin-(1-7) attenuates neointimal formation after stent implantation in the rat. Hypertension. 2005;45:138-141.
29. Mulvany MJ. Small artery remodeling and significance in the development of hypertension. News Physiol Sci. 2002;17:105-109.
30. Jain RK. Molecular regulation of vessel maturation. Nat Med. 2003;9:685-693.
31. Lindahl P, Johansson BR, Leveen P, Betsholtz C. Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science. 1997;277:242-245.
32. Blacque OE, Worrall DM. Evidence for a direct interaction between the tumor suppressor serpin, maspin, and types I and III collagen. J Biol Chem. 2002;277:10783-10788.