One-step exchange-labelling of pyridines and other N-heteroaromatics using deuterium gas: catalysis by heterogeneous rhodium and ruthenium catalysts

Tetrahedron Letters

Volumn 47, Issue 29, 2006, Pages 5025-5028

  Alexakis, Efstathios ^a   Jones, John R ^a   Lockley, William J S ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

Exchange; Deuteration; Deuterium gas; Isotope exchange; N Heteroaromatic; Pyridine; Rhodium black; Rhodium on alumina; Ruthenium black; Tritiation

Indexed keywords

DEUTERIUM; HETEROCYCLIC COMPOUND; PYRIDINE DERIVATIVE; RHODIUM DERIVATIVE; RUTHENIUM COMPLEX;

ARTICLE; CATALYSIS; CATALYST; ELECTRON TRANSPORT; ISOTOPE ANALYSIS; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; REDUCTION KINETICS; ROOM TEMPERATURE;

EID: 33744999883     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2006.05.106     Document Type: Article

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41. 4 requires 160.093 amu. The overall α-deuteration achieved by this procedure was 97.5 atom %.