The 50cc Penn State left ventricular assist device: A parametric study of valve orientation flow dynamics

ASAIO Journal

Volumn 52, Issue 2, 2006, Pages 123-131

  Kreider, James W ^a   Manning, Keefe B ^a   Oley, Leslie A ^a   Fontaine, Arnold A ^a   Deutsch, Steven ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; FLUID DYNAMICS; MACHINE DESIGN; MEDICAL IMAGING; VELOCITY MEASUREMENT;

MECHANICAL HEART VALVE; PARTICLE IMAGE VELOCIMETRY; VALVE ORIENTATION; VENTRICULAR ASSIST DEVICE;

BIOMEDICAL EQUIPMENT;

ARTICLE; HEART ASSIST DEVICE; HEART LEFT VENTRICLE; HEART VALVE; MITRAL VALVE; PROSTHESIS; THROMBUS; BLOOD FLOW VELOCITY; COMPARATIVE STUDY; EQUIPMENT DESIGN; FLOW KINETICS; HEART VALVE PROSTHESIS; HEMODYNAMICS; PHYSIOLOGY; THROMBOSIS;

BLOOD FLOW VELOCITY; EQUIPMENT DESIGN; HEART VALVE PROSTHESIS; HEART-ASSIST DEVICES; HEMODYNAMIC PROCESSES; MITRAL VALVE; RHEOLOGY; THROMBOSIS;

EID: 33744978557     PISSN: 10582916     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mat.0000199750.89636.77     Document Type: Article

References (23)

1. Heart Transplants and Statistics [American Heart Association Web site]. Available at: http://www.americanheart.org/presenter.jhtml? identifier=4588. Accessed September 12, 2005.
2. Rose EA, Moskowitz AJ, Packer M, et al: The REMATCH trial: rationale, design, and end points. Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure. Ann Thorac Surg 67: 723-730, 1999.
3. Mehta SM, Weiss WJ, Snyder AJ, et al: Testing of a 50 cc stroke volume completely implantable artificial heart: expanding chronic mechanical circulatory support to women, adolescents, and small stature men. ASAIO J 46: 779-782, 2000.
4. Deutsch S, Tarbell JM, Manning KB, et al: Experimental fluid mechanics of pulsatile artificial blood pumps. Annu Rev Fluid Mech 37: 65-86, 2006.
5. Bachmann C, Hugo G, Rosenberg G, et al: Fluid dynamics of a pediatric ventricular assist device. Artif Organs 24: 362-372, 2000.
6. Yamanaka H, Rosenberg G, Weiss WJ, et al: A multiscale surface evaluation of thrombosis in left ventricular assist systems. ASAIO J 49: 222, 2003.
7. Brown CH, Leverett LB, Lewis CH, et al: Morphological biochemical, and functional changes in human platelets subjected to shear stress. J Lab Clin Med 86: 462-471, 1975.
8. Sutera SP, Mehrjardi MH: Deformation and fragmentation of human red blood cells in turbulent shear flow. Biophys J 15: 000-10, 1975.
9. Sallam AM, Hwang NH: Human red blood cell hemolysis in a turbulent shear flow: Contribution of Reynolds shear stresses. Biorheology 21: 783-797, 1984.
10. Francischelli DE, Tarbell JM, Geselowitz DB: Local blood residence times in the Penn State artificial heart. Artif Organs 15: 218-224, 1991.
11. Konig CS, Clark C: Flow mixing and fluid residence times in a model of a ventricular assist device. Med Eng Phys 23: 99-110, 2001.
12. Yoganathan AP, Reul H, Black MM: Heart valve replacements: Problems and developments, in Hastings GW (ed), Cardiovascular Biomaterials, Berlin, Springer-Verlag, pp. 173-183, 1992.
13. Lu PC, Lai HC, Liu JS: A reevaluation and discussion on the threshold limit for hemolysis in a turbulent shear flow. J Biomech 34: 1361-1364, 2001.
14. Baldwin JT, Deutsch S, Geselowitz DB, Tarbell JM: LDA measurements of mean velocity and Reynolds stress fields within an artificial heart ventricle. J Biomech Eng 116: 190-200, 1994.
15. Hochareon P, Manning KB, Fontaine AA, et al: Fluid dynamic analysis of the 50 cc Penn State artificial heart under physiological operating conditions using particle image velocimetry. J Biomech Eng 126: 585-593, 2004.
16. Hochareon P, Manning KB, Fontaine AA, et al: Diaphragm motion affects flow patterns in an artificial heart. Artif Organs 27: 1102-1109, 2003.
17. Hochareon P, Manning KB, Fontaine AA, et al: Wall shear-rate estimation within the 50cc Penn State artificial heart using particle image velocimetry. J Biomech Eng 126: 430-437, 2004.
18. Hochareon P, Manning KB, Fontaine AA, et al: Correlation of in vivo clot deposition with the flow characteristics in the 50 cc Penn State artificial heart: a preliminary study. ASAIO J 50: 537-542, 2004.
19. Oley LA, Manning KB, Fontaine AA, Deutsch S: Off-design considerations of the 50cc Penn State Ventricular Assist Device. Artif Organs 29: 378-386, 2005.
20. Rosenberg G, Phillips WM, Landis D, Pierce WS: Design and evaluation of The Pennsylvania State University mock circulatory system. ASAIO J 4: 41-49, 1981.
21. Raffel M, Willert CE, Kompenhans J: Particle Image Velocimetry: A Practical Guide. Berlin, Springer-Verlag, 1998.
22. Hart DP: High speed PIV analysis using compressed image correlation. J Fluids Eng 120: 463-470, 1998.
23. Hart DP: Super-resolution by recursive local correlation. J Visualization 10: 000-10, 1999.